Ariadne M. Letra, D.D.S., M.S., Ph.D.

Professor / Interim Associate Dean for Research
University of Texas at Houston

I do not have any relevant financial / non-financial relationships with any proprietary interests.

Dr. Letra joined the UTHealth School of Dentistry faculty in 2011 to be part of the school’s Center for Craniofacial Research. She also holds an adjunct faculty position at the Department of Endodontics, and also at the Pediatric Research Center of UTHealth Medical School and the UT MDACC Graduate School of Biomedical Sciences. As a clinician-scientist specialized in endodontics and additional training in oral biology and human molecular genetics, Dr. Letra’s research focuses on understanding the genetic etiology and molecular mechanisms underlying complex oral traits in humans, including but not limited to craniofacial anomalies (particularly cleft lip and palate and tooth agenesis), as well as inflammatory conditions such as periapical disease. By combining human studies with in vitro and in vivo model systems, her research has elucidated the biological mechanisms underlying genetic variations in those conditions. Dr. Letra’s research has been supported by grants from the National Institutes of Health, the American Association of Endodontists Foundation, and the American Association of Orthodontists Foundation. She has lectured nationally and internationally and has published more than 80 peer-reviewed manuscripts and two book chapters in the fields of craniofacial genetics and endodontics.

Poster(s):

• (PR53) Dual-RNA Sequencing Technology Reveals Host-Pathogen Relationships in Apical Periodontitis