Autoimmune Diseases

W3 - Anti-CD45RC Antibody Immunotherapy Prevents and Treats Experimental Autoimmune Poly Endocrinopathy Candidiasis Ectodermal Dystrophy Syndrome

W8 - The B Cell Repertoire in Multiple Sclerosis Reveals Molecular Mimicry between EBV EBNA1 and GlialCAM

Tu6 - Identification of Novel DRB1*01:01-restricted T Cell Epitopes in Rheumatoid Arthritis

Tu9 - IL-6 Targeted Therapies Directed to Cytokine or Cytokine Receptor Blockade Drive Distinct Alterations in T Cell Function.

W10 - Intrathecal CD8+CD20+ T Cells in Primary Progressive Multiple Sclerosis

W21 - Reemergence of Pathogenic B Cell Clones in Autoimmune Myasthenia Gravis Tollowing B Cell Depletion Therapy

W22 - Kv1.3−/− Mice Do Not Develop CIA: A Novel Target with Small Molecules for Autoimmune Arthritis

W30 - Underlying T Cell Receptor Methylation Defects in Type 1 Diabetes Associated with Quantitative Defects

W32 - Therapeutic Effects of Anti-IFNg Therapy in a Spontaneous Mouse Model of Myositis

W36 - Plasma Levels of the MiR-193b/365a Cluster in Combination with Clinical Parameters Predict Response to Lactococcus Lactis-based Antigen-specific Combination Therapy

W37 - JAK Inhibition in a Patient with a STAT1 Gain-of-function Variant Reveals STAT1 Dysregulation as a Common Feature of Aplastic Anemia

W38 - Antigen-driven Ocular Immune Responses Distinguish Granulomatous and Non-granulomatous Uveitis

W43 - Combined Germline and Somatic FADD Mutations as a New Cause of Autoimmune Lymphoproliferative Syndrome

W47 - Immunometabolism Effect of Follicular Helper T Cells in Systemic Lupus Erythematosus

W50 - A Dysregulated CXCR3+CCR6+ Adaptive Immune Rheostat Exists in Patients with Active Enthesitis-related Arthritis

W59 - Deep Biology Approach for Development of Novel Therapeutics for Autoimmunity and Inflammation

W64 - Association of rs763361 C>T and rs727088 G>A SNPs of DNAM-1 with CRP Levels and BASDAI Index in Ankylosing Spondylitis Patients

W67 - Novel Therapy with Neddylation Inhibitor Delays the Progression of Disease in Pre-Diabetic Non-Obese Diabetic Mice by Restoring Endogenous Treg Function

Th37 - Clonally Expanded CD8 T Cells Are Recruited to the CSF in Neurosarcoidosis Through the Chemokine Receptors CXCR3 and CXCR4

Th45 - Autoreactive CD8+ T Cells are Restrained by an Exhaustion-like Program that is Maintained by LAG3

Th49 - Dysregulated Transferrin Receptor Disrupts T Cell Iron Homeostasis to Drive Inflammation in Systemic Lupus Erythematosus

Th52 - Childhood Idiopathic Nephrotic Syndrome is Characterized by Antigen-Experienced B-Cell Responses and Diminished Immunoregulation that are Differentially Targeted by Distinct Immunosuppressive Treatments

Th69 - Oral Mucosal Breaks Trigger Unique Systemic Immune Responses that Mediate Rheumatoid Arthritis

Th74 - Ex vivo Fold Expansion of Human Regulatory T Cells Negatively Correlates with Preservation of Beta Cell Function in Adolescent T1D subjects

Th75 - Reduced CD8 T Cell Exhaustion in DR4 Risk Subjects is Selectively Augmented with Abatacept in RA

Th89 - Increased Intrathecal Activity of Follicular Helper T Cells in Patients with Relapsing-Remitting Multiple Sclerosis

Th97 - Utilization of a Clinical Data Research Network to Improve Identification of Systemic Lupus International Collaborating Clinics Classification Criteria Attributes in Patients with Systemic Lupus Erythematosus

Th99 - Multi-omic Profiling in Celiac Disease Reveals Somatic Driver Mutations in Rogue T Cell Clones

Tu11 - High-Dimensional Immunophenotyping Reveals Altered Regulatory T Cell Fitness Between Inactive and Active Disease in Juvenile Idiopathic Arthritis

Tu12 - An In Silico Analysis to Predict the Function of Genes Associated with Type 1 Diabetes, Systemic Lupus Erythematosus, and Juvenile Idiopathic Arthritis in Colombian Patients

Tu14 - Functional and Molecular Characterization of Th2 Cell Subsets in Type 1 Diabetes

Tu18 - Targeted PD-1 Agonists as localized Immune Suppressants against Skin Autoimmune and Inflammatory Diseases

Tu19 - Multi-parametric Interrogation of the Systemic Lupus Erythematosus (SLE) Immunome Reveals Multiple Derangements

Tu41 - KIR+CD8+ T Cells Target Pathogenic T Cells and are Active in Autoimmune Diseases and COVID-19

Tu42 - JAK Inhibitor Ruxolitinib Prevents Autoimmune Diabetes in Non-Obese Diabetes Mice through Inhibition of the JAK-STAT Pathway in Multiple Cell Types

Tu43 - NaCl Exposure Results in Increased Expression and Processing of IL-1β in Meniere's Disease Patients

Tu48 - Naïve Arthritogenic SKG T Cells have a Defect in Anergy and a Repertoire Pruned by Superantigen

Tu62 - Impaired TIGIT Expression on B Cells Drives Circulating Tfh Cell Expansion in Multiple Sclerosis

Tu77 - Selective CD226 Knockout on Regulatory T Cells Reduces Diabetes in Female Non-obese Diabetic Mice

Tu79 - Searching for Environmental Triggers of Juvenile Dermatomyositis Using Antibody Profiling Technology

Tu91 - Evaluation of Indirect Immunofluorescent Assays for LGI1 Antibody Detection in Patients with Anti-LGI1 Encephalitis

W164 - Aging and Autoimmunity: Down Syndrome Gives a Master Class

W173 - Rosnilimab, a Novel PD-1 Agonist Monoclonal Antibody, Demonstrated Modulation of Peripheral T Cell Activity and Reduction of Circulating PD-1high Expressing CD4 and CD8 T Cells in a Phase 1 Healthy Volunteer Clinical Trial

Th171 - Gain of Function Mutation in SKAP2 Leading to Autoimmune Diabetes

Th177 - Understanding the T Cell Repertoire in Autoimmune Diseases Using High-dimensional Single-cell Analysis of Antigen-specific CD4+ and CD8+ T Cells

Th183 - Two Sources of Autoreactive T Cells in Patients with FOXP3 Mutations

Tu100 - A Pathogenic Th17/CD38+ Macrophage Feedback Loop Drives Inflammatory Arthritis Through TNFa

Tu106 - Phenotype-based Isolation of Antigen-specific CD4+ T Cells in Autoimmunity: A Study of Celiac Disease

Tu107 - Increased Monocyte Activity in Patients with Primary Progressive Multiple Sclerosis

Tu109 - SQZ® TAC Cell Therapy Platform Induces Antigen Specific T-regs and Prevents Onset of Type 1 Diabetes in Adoptive Transfer Models

Tu110 - Understanding Neuro-Immune Interactions in Multiple Sclerosis Brain by Single Nucleus Profiling

Tu123 - IL-23 Signaling Induces Autoimmune Disease Genes in Mucosal-associated Invariant T (MAIT) Cells

Tu130 - Central Nervous System-specific Chimeric Antigen Receptor Regulatory T Cells for the Therapy of Multiple Sclerosis

Tu132 - Induction of Antigen-Specific Immune Tolerance in Type 1 Diabetes by Antigen-Expressing Red Cell Therapeutics

Tu133 - Mass Cytometry Demonstrates an Extrafollicular T and B cell Signature that Correlates with Disease Activity in Pediatric Lupus Nephritis

Tu134 - High CD96 Expression Marks an IL-22 Producing CD4 T cell Population Reduced in Lupus Patients

Tu136 - Intravenous Ofatumumab Treatment of Multiple Sclerosis and Related Disorders: An Observational Study

Tu145 - STAT3 Gain-of-function Variants and T Cell-mediated Inflammation

Tu149 - Plasma from Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS) Induces Increased BBB Permeability Through Disruption of Tight Junction Proteins

Tu150 - Autoantibodies to Perilipin-1 Define a Subset of Acquired Generalized Lipodystrophy

Tu151 - GAD65 Mediated Inflammatory Immune Response In HLA-DR3/DQ2+ Type 1 Diabetes Patients

Tu152 - Senescence Associated DNA Damage in Lymph Node and Synovial Tissue Biopsies of Early Rheumatoid Arthritis Patients