(124) Effect of Hygroscopic Osmotic Dilator versus Foley Balloon on Cesarean Delivery Rates: A Bayesian Analysis

The trial enrolled 417 subjects. In the ITT analysis, the probability that the risk difference would be less than 10, 5, and 0 percentage points were 0.99, 0.99, and 0.89, respectively. The Bayesian mean risk difference estimate was -5.0 (95% credible interval −12.8 to 2.7, Table). Similar results were noted when performing the analysis on the PP population (Table). The probability that the risk difference would be less than 0 percentage points was 0.92, and the Bayesian mean estimate of the risk difference was -5.8 (95% credible interval −13.7 to 2.1, Table).


Conclusion: Dilapan-S has a high probability of decreasing cesarean rates in patients undergoing pre-induction cervical ripening compared with Foley balloon. Depending on price differences, the savings from lower cesarean and improved patient satisfaction may make Dilapan-S a suitable alternative to Foley.