Category: Clinical Obstetrics
Poster Session II
A multicenter retrospective computerized database study between 2005-2021. Women who had an index multifetal delivery and a subsequent singleton gestation in their next pregnancy were included. Maternal and neonatal outcomes of pregnancies following a short IPI ( < 6 months) were compared to those with an optimal IPI (18-48 months). The primary outcome of this study was the rate of preterm birth ( < 37 weeks). Secondary outcomes were adverse maternal and neonatal outcomes. Univariate analysis was followed by multiple logistic regression models; adjusted odds ratios (aORs) and 95% confidence intervals (CIs) were calculated.
Results: During the study period, 2,162 women had an index multifetal delivery followed by a singleton gestation in their next pregnancy at our medical centers; 134 (6.2%) had a short IPI, and 997 (46.1%) had an optimal IPI. Women with a short IPI were younger, with lower rates of previous cesarean and fertility treatments. Women with short IPI had higher rates of preterm labor < 37 weeks, anemia (Hb < 11 gr%) on admission to the delivery room and retained placental products following delivery, Table 1. This was confirmed on a multivariate analysis as well (aOR 2.26 (1.16–4.41), p = 0.02) for preterm delivery, Table 2.
Conclusion: Short IPI following a multifetal pregnancy is an independent risk factor for preterm delivery.
Ari Weiss, MD, MPH (he/him/his)
Shaare Zedek Medical Center, affiliated with the Hebrew University School of Medicine
Jerusalem, Yerushalayim, Israel
Hen Sela, MD
Shaare Zedek Medical Center
Jerusalem, Israel
Moshe Barg, MD
MD
Shaare Zedek Medical Center
Shaare Zedek Medical Center, Yerushalayim, Israel
Arnon Samueloff, MD
Shaare Zedek Medical Center
Jerusalem, Yerushalayim, Israel
Sorina Granovsky Grisaru, MD,PhD
head of Obstetrics & Gynecology, Shaare Zedek Medical Center, Jerusalem, Israel
Jerusalem, Yerushalayim, Israel
Misgav Rottenstreich, MBA, MD (he/him/his)
Clinical Fellow
McMaster University
Hamilton, Ontario, Canada