(904) Maternal bariatric surgery: a sibling-matched analysis comparing health of offspring born before and after surgery

The study population included 380,258 deliveries, 3,074 were of women who underwent bariatric surgeries (1,586 were before and 1,488 after the surgery). Offspring born after maternal bariatric surgeries were at a comparable risk for most morbidities (Table), besides endocrine related morbidities (3.2% vs. 5.2%, OR=1.68; 1.17-2.41) and obesity (2.5% vs. 4.1%, OR=1.61; 1.08-2.41). The risk for these morbidities was higher among offspring of mothers after versus before the surgery, although adjustment for maternal age and other confounding variables (Graph).

Conclusion:

While bariatric surgeries are considered an effective treatment for obesity, it seems to have less effect on offspring of women who underwent such surgeries. Other persistent factors are most likely associated with the offspring risk for morbidities, especially endocrine morbidities and obesity, which remain although the mother underwent bariatric surgeries.