OC 75 - Platelet Production from MKs

Moderator(s)

• 

  Alessandra Balduini, MD

  MD, PhD
  Department of Molecular Medicine
  University of Pavia, Pavia, Italy
  Pavía, Lombardia, Italy
• 

  Samantha Montague, PhD

  Postdoctoral Researcher
  Institute of Cardiovascular Sciences
  University of Birmingham
  Birmingham, England, United Kingdom

Presentations:

• 10:15 AM – 10:30 AM

  A 3D microvasculature assay reveals novel sub-cellular dynamics of megakaryocyte endothelial barrier interactions, proplatelet formation and release.
  

  Presenting Author: Nathan L. Asquith, N/A – Boston Children's Hospital; Harvard Medical School

  Co-Author: Daniela Freire – Boston Children's Hospital; Harvard Medical School

  Co-Author: Sarah Shelton – Massachusetts Institute of Technology

  Co-Author: Kellie Machlus, PhD – Vascular Biology Program, Boston Children's Hospital, Harvard Medical School

  Co-Author: Roger Kamm – Massachusetts Institute of Technology

  Co-Author: Joseph Italiano – Harvard Medical School
• 10:30 AM – 10:45 AM

  GP1b-FilaminA interaction regulates megakaryocyte localization and budding during platelet biogenesis
  

  Presenting Author: Marc L. Ellis, MBBS – Heart Research Institute, University of Sydney

  Co-Author: Antoine Terreaux – WEHI

  Co-Author: Rhyll Smythe – Heart Research Institute, The University of Sydney

  Co-Author: Anita Eckly – Université de Strasbourg, INSERM, EFS Grand-Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France

  Co-Author: Sue Cranmer – Monash University

  Co-Author: Jessica Maclean – Heart Research Institute, The University of Sydney

  Co-Author: Imala Alwis – Heart Research Institute, The University of Sydney

  Co-Author: Jose Perdomo – University of NSW

  Co-Author: Freda Passam – Heart Research Institute, University of Sydney

  Co-Author: Samir Taoudi – WEHI

  Co-Author: François Lanza – Université de Strasbourg, INSERM, EFS Grand-Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France

  Co-Author: Yuping Yuan – Heart Research Institute, University of Sydney

  Co-Author: Jackson Shaun – Heart Research Institute, University of Sydney
• 10:45 AM – 11:00 AM

  Platelet generation from circulating megakaryocytes is triggered in the lung vasculature
  

  Co-Author: Xiaojuan Zhao, Ph.D – University of Bristol

  Co-Author: Dominic Alibhai – University of Bristol

  Co-Author: Tony Walsh – University of Bristol

  Co-Author: Nathalie Tarassova – University of Bristol

  Co-Author: Semra Birol – University of Bristol

  Co-Author: Christopher Williams – University of Bristol

  Co-Author: Chris Neal – University of Bristol

  Co-Author: Elizabeth Aitken – University of Bristol

  Co-Author: Amie K. Waller, PhD – University of Cambridge

  Co-Author: Jose Ballester-Beltran – University of Cambridge

  Co-Author: Peter Gunning – University of New South Wales

  Co-Author: Edna Hardeman – University of New South Wales

  Co-Author: Ejaife O. Agbani, BPharm, MSc, PhD – University of Calgary

  Co-Author: Ingeborg Hers, PhD – University of Bristol

  Co-Author: Cedric Ghevaert, MD PhD – University of Cambridge

  Presenting Author: Alastair W. Poole – University of Bristol
• 11:00 AM – 11:15 AM

  Investigating the health and function of murine platelets generated using a new ex-vivo lung system
  

  Presenting Author: Nathalie Tarassova, MSc – University of Bristol

  Co-Author: Xiaojuan Zhao – University of Bristol

  Co-Author: Alastair W. Poole – University of Bristol
• 11:15 AM – 11:30 AM

  Platelet release device: From bench-scale to large culture platelet production
  

  Presenting Author: Anaïs Pongerard – Université de Strasbourg, INSERM, EFS Grand-Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France

  Co-Author: Léa Mallo, BSc – Université de Strasbourg, INSERM, EFS Grand-Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France

  Co-Author: Valentin Do Sacramento – Université de Strasbourg, INSERM, EFS Grand-Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France

  Co-Author: Olivier Boiron – CNRS, Université Aix-Marseille, Ecole Centrale Marseille, IRPHE UMR7342, F-13000 Marseille, France

  Co-Author: François Lanza – Université de Strasbourg, INSERM, EFS Grand-Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France

  Co-Author: Christian GACHET – Université de Strasbourg, INSERM, EFS Grand-Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France

  Co-Author: Yannick KNAPP, PhD – Université Avignon, LAPEC UPR4278, F-84000 Avignon, France

  Co-Author: Catherine Strassel – Université de Strasbourg, INSERM, EFS Grand-Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France