OC 28 - Coagulation Factors Beyond Hemostasis

Moderator(s)

• 

  Thomas Renné, MD PhD

  Chair, Professor of Clinical Chemistry, Director of the Institute
  Institute of Clinical Chemistry and Laboratory Medicine
  University Medical Centre Hamburg (UKE)
  Hamburg, Germany
• 

  Kimberly Martinod, PhD

  Assistant Professor
  Cardiovascular Sciences
  Center of Molecular and Vascular Biology, Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium
  Leuven, Vlaams-Brabant, Belgium

Presentations:

• 2:45 PM – 3:00 PM

  Factor X - Protease activated receptor-2 signaling in the regulation of diet-induced obesity
  

  Presenting Author: Dilraj Kaur, MSc – Center for Thrombosis and Hemostasis, University Medical Center Mainz

  Co-Author: Madhusudhan Thati – Center for Thrombosis and Hemostasis, University Medical Center Mainz

  Co-Author: Wolfram Ruf – Center for Thrombosis and Hemostasis, Johannes Gutenberg University Medical Center
• 3:00 PM – 3:15 PM

  Pathway-based Rare Variant Burden Analysis Identifies a Role for the Complement System in Purpura Fulminans
  

  Presenting Author: Pavan Bendapudi – Beth Israel Deaconess Medical Center

  Co-Author: Sumaiya Nazeen – Brigham and Women's Hospital

  Co-Author: Justine Ryu – Beth Israel Deaconess Medical Center

  Co-Author: Onuralp Soylemez – Brigham and Women's Hospital

  Co-Author: Betty Rouaisnel – Dana Farber Cancer Institute

  Co-Author: Meaghan Colling – Massachusetts General Hospital

  Co-Author: Bryce Pasko – Beth Israel Deaconess Medical Center

  Co-Author: Alissa Robbins – Dana Farber Cancer Institute

  Co-Author: Michael Bouzinier – Brigham and Women's Hospital

  Co-Author: Lindsay Tomczak – Beth Israel Deaconess Medical Center

  Co-Author: LIndsay Collier – Beth Israel Deaconess Medical Center

  Co-Author: Sanjay Ram – University of Massachusetts

  Co-Author: Agnes Toth-Petroczy – Brigham and Women's Hospital

  Co-Author: Elizabeth Fieg – Brigham and Women's Hospital

  Co-Author: Walter Dzik – Massachusetts General Hospital

  Co-Author: James Hudspeth – Boston Medical Center

  Co-Author: Olga Pozdnyakova – Brigham and Women's Hospital

  Co-Author: Richard Maas – Brigham and Women's Hospital

  Co-Author: Shamil Sunyaev – Brigham and Women's Hospital

  Co-Author: Julie-Aurore Losman – Dana Farber Cancer Institute
• 3:15 PM – 3:30 PM

  Coagulation factor XII induces persistent uPAR-integrin β1 signaling promoting DNA damage and senescence in diabetic kidneys
  

  Presenting Author: Ahmed Elwakiel, M.Sc. – Institute of laboratory medicine, clinical chemistry and molecular diagnostics, Leipzig University

  Co-Author: Khurrum Shahzad – Institute of laboratory medicine, clinical chemistry and molecular diagnostics, Leipzig University

  Co-Author: Ihsan Gadi – Institute of laboratory medicine, clinical chemistry and molecular diagnostics, Leipzig University

  Co-Author: Rajiv Rana – Institute of laboratory medicine, clinical chemistry and molecular diagnostics, Leipzig University

  Co-Author: Dheerendra Gupta, Msc – Institute of laboratory medicine, clinical chemistry and molecular diagnostics, Leipzig University

  Co-Author: Jayakumar Manoharan – Institute of laboratory medicine, clinical chemistry and molecular diagnostics, Leipzig University

  Co-Author: Shrey Kohli – Institute of laboratory medicine, clinical chemistry and molecular diagnostics, Leipzig University

  Co-Author: Thomas Renné – Institut für Klinische Chemie und Laboratoriumsmedizin, Zentrum für Diagnostik, UKE, Hamburg, Germany

  Co-Author: Berend Isermann – Institute of laboratory medicine, clinical chemistry and molecular diagnostics, Leipzig University
• 3:30 PM – 3:45 PM

  Protective Role of Plasminogen Deficiency in Non-Alcoholic Fatty Liver Disease and Glucose Dysmetabolism
  

  Presenting Author: Woosuk S. Hur, PhD – University of North Carolina at Chapel Hill

  Co-Author: Y-Van Nguyen – University of North Carolina at Chapel Hill

  Co-Author: Katharine C. King – University of North Carolina at Chapel Hill

  Co-Author: Yesha N. Patel – University of North Carolina at Chapel Hill

  Co-Author: Matthew J. Flick, PhD – University of North Carolina at Chapel Hill
• 3:45 PM – 4:00 PM

  Coagulation FXI regulates endothelial cell barrier function by inducing VE-cadherin proteolysis in an ADAM10-dependent manner
  

  Co-Author: Cristina Puy, PhD – Oregon Health & Science University

  Co-Author: Kelley R. Jordan – Oregon Health & Science University

  Co-Author: Nhu Nguyen – Oregn Health & Science University

  Co-Author: Christina U. Lorentz – Aronora, Inc.

  Co-Author: Erik I Tucker – Aronora, Inc.

  Co-Author: David Gailani – Vanderbilt University

  Presenting Author: Owen J. McCarty, PhD, FAHA – Oregon Health and Science University