Prologue: Overcoming Pitfalls in Moving Compounds From Preclinical Development to the Clinic: Examples From Bench to Bedside

Wednesday, October 19, 2022

8:30 AM – 9:00 AM ET

Location:254 A

Prologue Speaker(s)

Weirong Wang, PhD

Senior Scientific Director
Janssen R&D
Spring House, Pennsylvania

A high-level summary of the common challenges in preclinical/clinical translation and the strategies to mitigate these challenges. The presentation will focus on how mechanism-based PK/PD modeling can help bridge the gaps between in vitro/preclinical systems and clinical scenarios. It will also introduce the topics will be covered by other speakers.

Learning Objectives:

Upon completion, participant will be able to understand the common challenges moving compounds from preclinical stage to the clinic
Upon completion, participant will be able to understand a few mitigation stratigies to overcome the challenges during preclinical/clinic translation
Upon completion, participant will be able to understand how mechnism-based PK/PD modeling can help move compounds from preclinical stage to the clinic