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Poster Schedule
All Days
Mon, Oct 17
Tue, Oct 18
Wed, Oct 19
Poster Schedule
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Monday, October 17, 2022
9:30 AM – 10:30 AM
ET
(M0930-01-01) A Retrospective Analysis of Pharmacokinetic Variability between Fasting and Fasting-Sprinkle Bioequivalence Studies of Generic Modified-Release Drug Products: A Case Study on Esomeprazole Magnesium
Favorite
9:30 AM – 10:30 AM
ET
(M0930-01-03) Near-Infrared Light Triggered In Situ Cu(DDC)
2
Complex Formation and Reactive Oxygen Species Amplification Cascade for Cancer Therapy
Favorite
9:30 AM – 10:30 AM
ET
(M0930-01-04) Role of Propylene Glycol in the Transdermal Permeation of Clobetasol
Favorite
9:30 AM – 10:30 AM
ET
(M0930-01-05) Investigating Telmisartan Loaded Oral Microparticles Prepared by an Emulsion-Based Approach
Favorite
9:30 AM – 10:30 AM
ET
(M0930-01-06) Determination of Time-Temperature-Transformation Curve for Sulfonyl Urea Analogues in the Presence of a Crystallization Inhibitor using Simultaneous XRD-DSC
Favorite
9:30 AM – 10:30 AM
ET
(M0930-02-08) Development of an Aqueous Formulation of Immulina and the Evaluation of Its Anticancer Effect against B16 Melanoma
Favorite
9:30 AM – 10:30 AM
ET
(M0930-02-09) A 24 and 96 Well High-Throughput Renal Proximal Tubule MPS Model for Drug Development and Safety Studies
Favorite
9:30 AM – 10:30 AM
ET
(M0930-02-10) Debulking of SARS-CoV-2 and Influenza Virus Strains by Plant Viral Trap Proteins in Chewing Gums to Decrease Infection and Transmission
Favorite
9:30 AM – 10:30 AM
ET
(M0930-02-11) A Novel Fed State Approach to the Application of the Developability Classification System
Favorite
9:30 AM – 10:30 AM
ET
(M0930-02-12) In Vitro and In Vivo Assessment of Vitamin E Acetate’s Potential Role in Causing the Marijuana/THC 2019 EVALI Outbreak
Favorite
9:30 AM – 10:30 AM
ET
(M0930-03-13) Development and Characterization of Primaquine and Chloroquine Solid Dispersion Loaded Dissolving Microneedles for the Improved Treatment of Malaria
Favorite
9:30 AM – 10:30 AM
ET
(M0930-03-14) Enhancement of Raloxifene Hydrochloride Bioavailability by Solubility Improvement and Metabolism Inhibition Employing Hot-Melt Extrusion
Favorite
9:30 AM – 10:30 AM
ET
(M0930-03-15) Novel Fast Track Method for Stability Studies of Amorphous Solid Dispersions via Powder X-ray Diffraction and Vacuum Compression Molding
Favorite
9:30 AM – 10:30 AM
ET
(M0930-03-17) Study of High Dose Vitamin C (1000 mg) ER Hydrophilic Matrix Tablet using METHOCEL™ as the Rate Controlling Polymer
Favorite
9:30 AM – 10:30 AM
ET
(M0930-04-19) Investigational Vaccine Induces Immune Correlates of Protection and Resistance to Infection against
Neisseria gonorrhoeae
in Mice
Favorite
9:30 AM – 10:30 AM
ET
(M0930-04-20) Comparative Study of Capsule-Based DPIs for Drug Detachment from Carrier Particles in Interactive Blends
Favorite
9:30 AM – 10:30 AM
ET
(M0930-04-21) Dual Functionality of Bile Acid: Physical Stabilization of Drugs in the Amorphous State and Solubility Enhancement in Solution
Favorite
9:30 AM – 10:30 AM
ET
(M0930-04-22) Low Endotoxin Recovery (LER) Effect in Sample Solution of Monoclonal Antibody in Sodium Phosphate Dibasic and Citric Acid Anhydrous Constitution Buffer Analyzed with LAL Turbidimetric Kinetic Assay
Favorite
9:30 AM – 10:30 AM
ET
(M0930-04-24) Developing Efficient Bioequivalence Approaches for Generic Vaginal Drug Products
Favorite
9:30 AM – 10:30 AM
ET
(M0930-05-25) Analysis of DBS Microsamples in a Validated Serum Method
Favorite
9:30 AM – 10:30 AM
ET
(M0930-05-26) Distinguishing Tobacco-Derived Nicotine from Synthetic Nicotine in Commercial Nicotine Samples
Favorite
9:30 AM – 10:30 AM
ET
(M0930-05-28) Therapeutic Anticancer Efficacy of Intra-Tumoral Controlled Osmotic-Driven Delivery of Bioactive IL-2 Using Novel Visible-Light Photocured Biodegradable Injectable Elastomeric Implants
Favorite
9:30 AM – 10:30 AM
ET
(M0930-05-29) Piperlongumine Reverses EGFR Resistance as an Adjuvant Treatment in Lung Cancer Cells
Favorite
9:30 AM – 10:30 AM
ET
(M0930-06-31) Identifying Protein Aggregation through UV-Visible Absorption Spectroscopy
Favorite
9:30 AM – 10:30 AM
ET
(M0930-06-32) Method for the Analysis and Quantitation of Pharmaceutical Counterions Utilizing Hydrophilic Interaction Liquid Chromatography
Favorite
9:30 AM – 10:30 AM
ET
(M0930-06-33) Wavelength Selection Method Based on Partial Least Square for Determination of Quetiapine in Tablets
Favorite
9:30 AM – 10:30 AM
ET
(M0930-06-34) Stability of Medications Used by Qatar’s Ambulance Service in Rapid Response Vehicles: Protocol Development
Favorite
9:30 AM – 10:30 AM
ET
(M0930-06-35) Dust Emissions of Surrogate Substances Resulting from Diffusive and Convective Transport for Containment Investigations with a Newly Developed Two-Chamber Setup
Favorite
9:30 AM – 10:30 AM
ET
(M0930-06-36) Particulate Contamination on Medical Devices and Single Use Systems
Favorite
9:30 AM – 10:30 AM
ET
(M0930-07-38) Immune Cells Activating Biotin-Decorated PLGA Protein Carrier
Favorite
9:30 AM – 10:30 AM
ET
(M0930-07-39) Developing an In Vitro System to Emulate the In Vivo Subcutaneous Environment and Predict the Fate of Drugs in Subcutaneous Delivery: Assessment of Biologics
Favorite
9:30 AM – 10:30 AM
ET
(M0930-07-40) Light Activatable Prodrug Strategy to Treat Non-muscle Invasive Bladder Cancer
Favorite
9:30 AM – 10:30 AM
ET
(M0930-07-41) Surface-Modified Inhalable Microparticle-Encapsulated Triterpenoid for Enhanced Efficacy in Malignant Mesothelioma
Favorite
9:30 AM – 10:30 AM
ET
(M0930-08-43) Moisture Endpoint Detection and Scale Up for Top Spray Granulation Technology
Favorite
9:30 AM – 10:30 AM
ET
(M0930-08-44) Accelerated Technology Transfer for the Development and Commercialization of Fexuprazan Using Compaction Simulation
Favorite
9:30 AM – 10:30 AM
ET
(M0930-08-45) Use of Predictive Dissolution to Guide Formulation Development - A Case Study of a Weak Base Drug in Conventional and Enabled Oral Formulations
Favorite
9:30 AM – 10:30 AM
ET
(M0930-08-47) Microalgae as Cell Factories for Antiviral Protein Production
Favorite
9:30 AM – 10:30 AM
ET
(M0930-09-49) Comparative Study of Protein Precipitation, Solid-Phase Extraction and Phospholipid Removal for Simultaneous Quantification of Serotonin, Dopamine, and Norepinephrine by LC-MS/MS in the Mouse Brain
Favorite
9:30 AM – 10:30 AM
ET
(M0930-09-50) Robustness Testing of an Assay for Flow Cytometric CAR Persistence Determination
Favorite
9:30 AM – 10:30 AM
ET
(M0930-09-51) An Emerging Derivatization Strategy for Minimizing Matrix Effect in Metabolomics Analysis
Favorite
9:30 AM – 10:30 AM
ET
(M0930-09-52) Characterization of Lipid Nanoparticle (LNP) Composition UHPLC-CAD
Favorite
9:30 AM – 10:30 AM
ET
(M0930-09-53) Evaluation of Gender Differences in Mycophenolic Mofetil-Induced Gastrointestinal Toxicity in Rats using a Novel LC-MS/MS Method
Favorite
9:30 AM – 10:30 AM
ET
(M0930-09-54) Quantitative Expression of Stemness Markers to Identify Metastatic Potential of Triple-Negative Breast Cancer Cells: Prognostic Signature for Personalized Treatment
Favorite
9:30 AM – 10:30 AM
ET
(M0930-10-55) Vocacapsaicin (formerly CA-008): A Water-Soluble Prodrug for Rapid Release of Capsaicin for the Treatment of Post-Surgical Pain
Favorite
9:30 AM – 10:30 AM
ET
(M0930-10-56) Bioengineered Extracellular Vesicles (EV) Enhance Innate EV Mitochondrial Load and Mitochondrial Functions in Ischemic Brain Endothelium
Favorite
9:30 AM – 10:30 AM
ET
(M0930-10-57) Targeted Liposomes for Selective Delivery of Cisplatin to Ovarian Cancer
Favorite
9:30 AM – 10:30 AM
ET
(M0930-10-58) Modulation of the Activity of Histone Lysine Methylation Writers and Erasers in Leukemia Cells by a Curcumin Analog
Favorite
9:30 AM – 10:30 AM
ET
(M0930-10-59) Implementing of Next-Generation Sequencing-Based Approach for Pharmacogenomics Profiling and Exploring Its Potential Clinical Utilities
Favorite
9:30 AM – 10:30 AM
ET
(M0930-11-61) Cannabidiol Loaded Extracellular Vesicles from Human Umbilical Cord Mesenchymal Stem Cells Alleviate Paclitaxel Induced Peripheral Neuropathy
Favorite
9:30 AM – 10:30 AM
ET
(M0930-11-62) Efficacy Difference of Antipsychotics in Alzheimer's Disease and Schizophrenia: Explained with Network Efficiency and Pathway Analysis Methods
Favorite
9:30 AM – 10:30 AM
ET
(M0930-11-63) Evaluation of Phosphorylated Neurofilament Heavy Chain (pNF-H) as a Biomarker to Bridge Riluzole Treatment and Motor Outcomes in Patients with Acute Spinal Cord Injury (SCI)
Favorite
9:30 AM – 10:30 AM
ET
(M0930-11-65) A Mechanistic PBPK Model for Maraviroc to Elucidate the Dose Related Non-Linearity in Oral Absorption using a Middle-Out Approach
Favorite
9:30 AM – 10:30 AM
ET
(M0930-12-67) Liposome as a Carrier for Delivery of Cannabidiol and pAPOE2 for the Management of Alzheimer's Disease
Favorite
9:30 AM – 10:30 AM
ET
(M0930-12-68) Ethyl Cellulose Coated Polymeric Microneedles for Sampling of Drugs and Biomarkers from the Tissues
Favorite
9:30 AM – 10:30 AM
ET
(M0930-12-69) Phyto-Nano-Silver containing Lipo-Carriers for the Treatment of Thermal Burn Wounds
Favorite
9:30 AM – 10:30 AM
ET
(M0930-12-70) Amorphous Lactose Solid Dispersion Co-Spray Dried with Magnesium Stearate as a Novel Lactose Carrier
Favorite
9:30 AM – 10:30 AM
ET
(M0930-02-07) Using the In Vitro Dissolution Absorption System (IDAS) to Evaluate the Effects of Excipients on the Permeation of Putative Biopharmaceutics Classification System Class III Drugs
Favorite
9:30 AM – 10:30 AM
ET
(M0930-12-72) Co-processed Hydroxypropyl Methylcellulose–Mannitol as a Directly Compressible Excipient for Controlled Release
Favorite
10:30 AM – 11:30 AM
ET
(M1030-01-01) HA Nanogel/Spike Protein Complex Induces One-Year Persistent Antibody Production
Favorite
10:30 AM – 11:30 AM
ET
(M1030-01-02) Biomimetic SARS-CoV-2 Spike Protein Nanoparticles as Viral Inhibitors against COVID-19
Favorite
10:30 AM – 11:30 AM
ET
(M1030-01-03) In Vitro Permeability Comparison Study: Skin versus Two Biomimetic Barrier Permeapad™ and SCM
Favorite
10:30 AM – 11:30 AM
ET
(M1030-01-04) How Do Extracellular Vesicles Enter Recipient Brain Endothelial Cells?
Favorite
10:30 AM – 11:30 AM
ET
(M1030-01-05) Intrinsic Dissolution of New Pharmaceutical Film Coating Systems
Favorite
10:30 AM – 11:30 AM
ET
(M1030-01-06) Development of a Child-Friendly Antibiotic Packed Multiparticulate Oral Sprinkle Formulation for Tuberculosis Pharmacotherapy
Favorite
10:30 AM – 11:30 AM
ET
(M1030-02-07) Establishment of Preclinical Mechanistic In Vitro-In Vivo Correlations for Long-Acting Injectable Suspensions
Favorite
10:30 AM – 11:30 AM
ET
(M1030-02-08) Biogenesis and Secretion Modulation of Brian Endothelial Cell-Derived Exosome for the Brain Delivery of Therapeutic Agents
Favorite
10:30 AM – 11:30 AM
ET
(M1030-02-09) Assessment of Pre-existing AAV8 Neutralizing Antibody and Total Binding Antibody Assays for Patient Selection
Favorite
10:30 AM – 11:30 AM
ET
(M1030-02-11) A Pharmacokinetic Evaluation of Mitraciliatine, a Kratom Alkaloid in Rats
Favorite
10:30 AM – 11:30 AM
ET
(M1030-02-12) In Vitro Evaluation of CAR-T Cell Cytotoxicity Using Flow Cytometry for the Development of a Potency Assay
Favorite
10:30 AM – 11:30 AM
ET
(M1030-03-13) Employing Hot-Melt Extrusion Technology to Enhance the Solubility of Cannabidiol (CBD)
Favorite
10:30 AM – 11:30 AM
ET
(M1030-03-14) Hot-Melt Extrusion as a Novel Technique to Develop Polymeric Micelles for Drug Delivery
Favorite
10:30 AM – 11:30 AM
ET
(M1030-03-15) Predicting the Pharmacokinetics of Amorphous Dispersions Using Canine PBPK Models
Favorite
10:30 AM – 11:30 AM
ET
(M1030-03-16) Investigation of Thermoelastic Properties of a Novel Extrudable Polymer Poly-2-ethyl-tetra-oxazoline (PETOX) for the Development of Amorphous Solid Dispersions by Hot Melt Extrusion
Favorite
10:30 AM – 11:30 AM
ET
(M1030-03-17) Spray Drying of Amorphous Solid Dispersions (ASDs): Small Scale Screening of Batches containing Less than 50 mg API
Favorite
10:30 AM – 11:30 AM
ET
(M1030-04-19) Influence of Varying Amount of an Inactive Ingredient on the Microstructure and Performance of Metronidazole Topical Gels
Favorite
10:30 AM – 11:30 AM
ET
(M1030-04-20) Amorphous Solid Dispersions for Enhancement of Equilibrium Aqueous Solubility of Sulfamethoxazole
Favorite
10:30 AM – 11:30 AM
ET
(M1030-04-21) Practical Preparation of Reproducible PLGA Nanoparticle for Intravenous Drug Administration
Favorite
10:30 AM – 11:30 AM
ET
(M1030-04-22) Control of Recrystallization in Tablets Containing Amorphous Solid Dispersion
Favorite
10:30 AM – 11:30 AM
ET
(M1030-04-23) Use of Mega Beads in Designing a Single Unit Biphasic Dosage Form
Favorite
10:30 AM – 11:30 AM
ET
(M1030-04-24) Sustained Release Orally Disintegrating Tablets (ODTs) Comprising Coated Microparticles to Improve Acceptability in Patients with Dysphagia
Favorite
10:30 AM – 11:30 AM
ET
(M1030-05-25) Screening of FDA-Approved Drug Library against Vancomycin Resistant Enterococci
Favorite
10:30 AM – 11:30 AM
ET
(M1030-05-26) The Tumor Microenvironment in Three-Dimensions: Immune Cells, Cytokines, and Tumor Invasion
Favorite
10:30 AM – 11:30 AM
ET
(M1030-05-28) Solubility Prediction Using Manifold Embedding of Molecular Surface
Favorite
10:30 AM – 11:30 AM
ET
(M1030-05-29) Computational Toxicity Prediction for Compounds of Unknown Toxicity using Bulk RNA-Seq: A Case of Liver Toxicity
Favorite
10:30 AM – 11:30 AM
ET
(M1030-05-30) Analysis of Amino Acid Content in Commercially Available Supplements
Favorite
10:30 AM – 11:30 AM
ET
(M1030-06-32) Aerodynamic Performance of Spray Dried Cannabidiol Powder for Efficient Pulmonary Delivery
Favorite
10:30 AM – 11:30 AM
ET
(M1030-06-33) Loss In Weight Feeding Optimization in a Continuous Drug Product Manufacturing Line
Favorite
10:30 AM – 11:30 AM
ET
(M1030-06-34) Experimental and Theoretical Investigation of Rotary Atomization Dynamics for Control of Lipid Multiparticulate (LMP) Particle Size during Spray Congealing Process
Favorite
10:30 AM – 11:30 AM
ET
(M1030-06-35) Physicochemical Characterisation of Piroctone Olamine for Topical Delivery to the Skin
Favorite
10:30 AM – 11:30 AM
ET
(M1030-07-37) Taste Optimization in Oral Dosage Forms: A Sensory Panel Study with the Focus on High-Intensity Sweeteners
Favorite
10:30 AM – 11:30 AM
ET
(M1030-07-38) Development of Lipid Formulation for Oral Delivery of Proteins and Peptides with Poor Permeability
Favorite
10:30 AM – 11:30 AM
ET
(M1030-07-39) Days or Centuries? Predicting the Shelf-Life of ASDs
Favorite
10:30 AM – 11:30 AM
ET
(M1030-07-40) Fabrication of Drug-Loaded Polymeric Micelles Using Homo-PEG as Both the Solvent and the Lyoprotectant for Freeze-Drying
Favorite
10:30 AM – 11:30 AM
ET
(M1030-07-41) Biorelevant Dissolution Method Considerations for the Appropriate Evaluation of Amorphous Solid Dispersions: Are Two Stages Necessary?
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10:30 AM – 11:30 AM
ET
(M1030-08-43) Quality Assurance Practices for Transportation of Oncology Treatments: The Case Study of Drones
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10:30 AM – 11:30 AM
ET
(M1030-08-44) Probing Surface Chemical Analysis of Banana Starches in Functional Applications
Favorite
10:30 AM – 11:30 AM
ET
(M1030-08-45) Novel 3D Printed Modular Tablets containing Multiple Anti-viral Drugs: High Precision Drop-on-Demand Drug Deposition
Favorite
10:30 AM – 11:30 AM
ET
(M1030-08-47) Kilo Scale Synthesis in Daisy Chained Flow Reactors
Favorite
10:30 AM – 11:30 AM
ET
(M1030-09-49) A Simple, Rapid Method for Simultaneous Quantitative Analysis of Dithiothreitol and Dihydroxy-1,2-dithiane in Cell Culture Media by LC/MS/MS
Favorite
10:30 AM – 11:30 AM
ET
(M1030-09-50) Development of an Automated and High Throughput UHPLC/MS Based Workflow for Cleaning Verification of Potent Compounds in the Pharmaceutical Manufacturing Environment
Favorite
10:30 AM – 11:30 AM
ET
(M1030-09-51) Innovative Application of ICP-MS Technology in Discovery and Early Development of Radioligand Therapeutics
Favorite
10:30 AM – 11:30 AM
ET
(M1030-09-52) Overcoming Quantitative Challenges in Bioanalysis of Small Molecules Using the MRM
3
and Q0 Dissociation Approaches on the SCIEX 7500 System
Favorite
10:30 AM – 11:30 AM
ET
(M1030-09-54) Quantitative Analysis of levo-alpha-acetyl-methadol (LAAM) in Rabbit Plasma for A Pharmacokinetic Study of Multiple Dosage Forms
Favorite
10:30 AM – 11:30 AM
ET
(M1030-12-67) Comparative Evaluation of In Vitro Release Profile of Hydrogen Sulfide from Its Donors
Favorite
10:30 AM – 11:30 AM
ET
(M1030-12-68) Perfluorocarbon Nanoemulsions as Artificial Oxygen Carriers–Initial Proof-of-Concept to In Vitro Tissue Culture Efficacy
Favorite
10:30 AM – 11:30 AM
ET
(M1030-12-69) Terbinafine and Ciclopirox Ungual Delivery from New Vehicles across Porated and Non-porated Human Nails
Favorite
10:30 AM – 11:30 AM
ET
(M1030-12-70) Solubility Enhancement of BCS Class IV Drug Acyclovir Using Hot Melt Extrusion
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10:30 AM – 11:30 AM
ET
(M1030-12-71) Equilibrium Solubility and Solute-Solvent Interactions of Four Drugs in Mono-Solvents
Favorite
10:30 AM – 11:30 AM
ET
(M1030-12-72) Enhancement of Crystal Nucleation at a Liquid/Vapor Interface
Favorite
11:30 AM – 12:30 PM
ET
(M1130-01-02) Impact of Granulation Solvent on Release Performance of Dual Matrix Extended-Release Tablets of Highly Water-Soluble Drugs Formulated Using Compritol
®
888ATO and Methocel
®
as Release Retarding Agents
Favorite
11:30 AM – 12:30 PM
ET
(M1130-01-03) Using Design of Experiments (DoE) in Validation of Camo-peg NL Formulation
Favorite
11:30 AM – 12:30 PM
ET
(M1130-01-04) Hydrogel-Forming Microarray Patches Combined with Poly(ethylene)glycol Reservoirs for the Long-Acting Intradermal Deposition of a Poorly-Soluble Drug
Favorite
11:30 AM – 12:30 PM
ET
(M1130-01-05) Evaluating Influence of Critical Quality Attributes of Metronidazole Topical Gel on Bioequivalence Using the Dermal Virtual Bioequivalence (VBE) Module in Simcyp Simulator
Favorite
11:30 AM – 12:30 PM
ET
(M1130-01-06) A One-Two Punch Extracellular Vesicle Delivery System: Innate EV Mitochondria and EV/HSP27 Protect the Ischemic Brain Endothelium
Favorite
11:30 AM – 12:30 PM
ET
(M1130-02-07) Comparative In Vivo Stability of Tumor Targeting Antibodies Labeled Using Three Distinct Radioiodination Methods
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11:30 AM – 12:30 PM
ET
(M1130-02-08) Sex Hormone-Dependent Regulation of MCT1 on the Blood Brain Barrier
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11:30 AM – 12:30 PM
ET
(M1130-02-09) Establishment of Preclinical Immunotoxicity Reference Based on a Large-Scale Immunophenotyping Data in Cynomolgus Monkey
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11:30 AM – 12:30 PM
ET
(M1130-02-11) CNS Delivery of Novel DNA Damage Response (DDR) Inhibitors for the Treatment of Brain Tumors
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11:30 AM – 12:30 PM
ET
(M1130-02-12) Biocompatibility Assessment of a 3D-Printed Cardiovascular Stent
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11:30 AM – 12:30 PM
ET
(M1130-03-13) Impact of Host Physiological and Pathological Conditions on the Activity of Gut Microbial Beta-Glucuronidases toward Hydrolysis of Baicalin
Favorite
11:30 AM – 12:30 PM
ET
(M1130-03-15) Novel Lipid Nanoparticles for Potential mRNA Delivery Vaccine Applications
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11:30 AM – 12:30 PM
ET
(M1130-03-16) Printability of Pharmaceutical Fused Deposition Modeling (FDM) Feedstock Material: Mechanical Characterization of FDM Filaments and the FDM 3D Printing Process
Favorite
11:30 AM – 12:30 PM
ET
(M1130-03-18) Developing In Vitro Lipolysis Model for Real-Time Analysis of Drug Concentrations during Digestion of Lipid-Based Formulations
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11:30 AM – 12:30 PM
ET
(M1130-04-19) Stability and Optimization Study of Cisplatin/Hyaluronan Film for Loco-Regional Drug Delivery in Cancer
Favorite
11:30 AM – 12:30 PM
ET
(M1130-04-21) Penetratin and Transferrin Functionalized Liposomes Can Deliver Losartan Potassium to the Brain of Wistar Kyoto Rats
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11:30 AM – 12:30 PM
ET
(M1130-04-22) Anticancer Activity and Pulmonary Delivery of an Antimicrobial Peptide, Nisin ZP, for Non-Small Cell Lung Cancer (NSCLC) Treatment
Favorite
11:30 AM – 12:30 PM
ET
(M1130-04-24) The Impact of Cyclodextrin on Fasting and Fed Bioequivalence Studies in Solid Oral Immediate-Release Drug Products
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11:30 AM – 12:30 PM
ET
(M1130-05-26) Hit to Lead Optimization Studies of Meta Substituted Enaminone Derivatives as Potential Anti-Seizure Agents for Generalized and Drug-Resistant Epilepsy
Favorite
11:30 AM – 12:30 PM
ET
(M1130-05-27) Novel Materials and Formulations for Driving Intracellular Delivery of Macrocyclic Peptides
Favorite
11:30 AM – 12:30 PM
ET
(M1130-05-28) CNS Distributional Kinetics of Panobinostat in the Mouse Models
Favorite
11:30 AM – 12:30 PM
ET
(M1130-05-29) Development of Novel Macropinocytosis Inducers to Enhance Cellular Uptake of Small and Large Molecules
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11:30 AM – 12:30 PM
ET
(M1130-05-30) Intravitreal Infusion of Drugs Using Eudragit Coated Microneedles
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11:30 AM – 12:30 PM
ET
(M1130-06-31) Impact of Freezing Process Parameters on Jurkat Cell Cryopreservation
Favorite
11:30 AM – 12:30 PM
ET
(M1130-06-32) Investigating Pharmaceutical Frozen Solution Using 31P and
1
H Solid-State NMR
Favorite
11:30 AM – 12:30 PM
ET
(M1130-06-33) Continuous Manufacturing of Inhalation Powders: Effects of Processing Parameters
Favorite
11:30 AM – 12:30 PM
ET
(M1130-06-34) A Mathematical Model as a Tool to Optimize the 3D Printing Design for Tablet Dosage Form
Favorite
11:30 AM – 12:30 PM
ET
(M1130-07-37) Spleen-Targeting Delivery of Small Circular RNA Vaccines
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11:30 AM – 12:30 PM
ET
(M1130-07-38) Evaluation of Surface-Modified PLGA Nanoparticles to Enhance Absorption of Sorafenib for the Treatment of Liver Cancer
Favorite
11:30 AM – 12:30 PM
ET
(M1130-07-39) Nanodisc Delivery of Liver X Receptor Agonist for the Treatment of Diabetic Nephropathy
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11:30 AM – 12:30 PM
ET
(M1130-07-40) The Effects of 3D-Printing Polyhedron Mini-tablets and Their Drug Delivery Kinetic Models
Favorite
11:30 AM – 12:30 PM
ET
(M1130-07-41) Optimization of Novel Platinum Based Cyanide Scavengers: In Vitro Prioritization
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11:30 AM – 12:30 PM
ET
(M1130-07-42) Fabrication of a Core-Shell Model for Combinational Drug Delivery via Hot Melt-Extrusion Paired with 3D Printing
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11:30 AM – 12:30 PM
ET
(M1130-08-43) Final Sterile Filtration of Lentivirus
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11:30 AM – 12:30 PM
ET
(M1130-08-44) Bioavailability Improvement through Particle Engineering
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11:30 AM – 12:30 PM
ET
(M1130-08-45) Predicting Tablet Properties Using In-Line Measurements and Evolutionary Equation Discovery
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11:30 AM – 12:30 PM
ET
(M1130-08-46) Purification and Heat Inactivation of an Oxidation Prone Protein: Study of Hemoglobin
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11:30 AM – 12:30 PM
ET
(M1130-09-50) Volumetric Absorptive Microsampling Method as a Better Blood Sampling Tool for the Therapeutic Drug Monitoring of Everolimus in Liver Transplant Recipients
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11:30 AM – 12:30 PM
ET
(M1130-09-51) Development and Validation of an LC-MS/MS Method for Determination of Difelikefalin in Human Plasma
Favorite
11:30 AM – 12:30 PM
ET
(M1130-09-52) NOHA: A Novel Biomarker to Monitor Treatment Outcome in Triple-Negative Breast Cancer Patients
Favorite
11:30 AM – 12:30 PM
ET
(M1130-09-53) Comparing Chromatic and Fluorometric Methods for Gentamicin Sulfate Detection by Ninhydrin Complexing and
o
-phthaldialdehyde Reagent
Favorite
11:30 AM – 12:30 PM
ET
(M1130-09-54) Bridging Two Generations of Commercial ELISA Kits for Residual Vero Cell Host Cell Protein (HCP) Control in Live Virus Vaccines
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11:30 AM – 12:30 PM
ET
(M1130-10-55) Combination of Thymoquinone and Curcumin Induces Cell Death by Alteration of Redox Homeostasis in A375 Melanoma Cell Line
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11:30 AM – 12:30 PM
ET
(M1130-10-56) Screening of Significant Molecular Descriptors Affecting Particle Size: A Smart Exemplary to Developing Efficient Lipid-Based Delivery Systems in Pre-formulation Studies
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11:30 AM – 12:30 PM
ET
(M1130-10-57) Development and Verification of Physiologically-Based Pharmacokinetic (PBPK) Model for Vaginal Administration of Dapivirine Ring and Gel Formulation
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11:30 AM – 12:30 PM
ET
(M1130-10-58) Drug Repurposing: A Therapeutic Approach to Modulate Immune Microenvironment in Pancreatic Cancer
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11:30 AM – 12:30 PM
ET
(M1130-10-59) Systems Biology Modeling of the Insulin Signaling Network in the Blood-Brain Barrier Endothelium Predicts Cerebrovascular Inflammation in Alzheimer’s disease
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11:30 AM – 12:30 PM
ET
(M1130-11-61) Systematic In Silico Analysis of Clinically Tested Drugs for Reducing Amyloid-Beta Plaque Accumulation in Alzheimer's disease
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11:30 AM – 12:30 PM
ET
(M1130-11-62) An Integrative Deep Learning Model to Identify Important Lab Tests from Electronic Medical Records for the Prediction of Suicide-Related Events Among Post-Traumatic Stress Disorder Patients
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11:30 AM – 12:30 PM
ET
(M1130-11-63) Physiologically Based Pharmacokinetic (PBPK) Modelling of Cabotegravir to Evaluate the Feasibility of Drug Delivery via Microarray Patches for the Treatment of HIV in Children
Favorite
11:30 AM – 12:30 PM
ET
(M1130-11-64) Assessing the Impact of Excipient and Food Intake on Bioequivalence Using PBPK and Virtual Bioequivalence Trial: A Case Example with Acyclovir Immediate Release Tablets
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11:30 AM – 12:30 PM
ET
(M1130-11-65) A Retrospective Study of Mid-review Cycle Meetings (MRCMs) within Generic Drug User Fee Amendments (GDUFA) II
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11:30 AM – 12:30 PM
ET
(M1130-12-67) Anti-SARS-CoV-2 Nasal Powders: Manufacturing, Ex Vivo Drug Accumulation/Transport in Rabbit Nasal Mucosa and In Vitro Virus Inhibition
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11:30 AM – 12:30 PM
ET
(M1130-12-68) Hydroalcoholic Media Effects on Ibuprofen Release from Low Acyl Gellan Gum
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11:30 AM – 12:30 PM
ET
(M1130-12-69) Release of Vaccine Nanoparticles from Hydrogels Intended for HIV Immunization
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11:30 AM – 12:30 PM
ET
(M1130-12-70) Development and Evaluation of Transdermal Delivery System of Tranylcypromine for the Treatment of Depression
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11:30 AM – 12:30 PM
ET
(M1130-09-49) Nanoparticle-Mediated Delivery of miRNA Mimics for Gene Therapy
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11:30 AM – 12:30 PM
ET
(M1130-12-72) Inulin-Based Dual-Function Polymer for Enhanced Delivery of Nucleic Acids to the Kidney
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12:30 PM – 1:30 PM
ET
(M1230-01-02) Ionizable Lipid Nanoparticles for Precise Intracellular Delivery of CpG DNA Adjuvant
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12:30 PM – 1:30 PM
ET
(M1230-01-03) Characterization of the Enteric Performance of an Innovative Functional Capsule
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12:30 PM – 1:30 PM
ET
(M1230-01-04) Development of 3D-Printed Gastro-Retentive Sustained Release Mini Device Using Ingestible Compounds
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12:30 PM – 1:30 PM
ET
(M1230-01-05) Digital Light Processing (DLP) 3D Printed Tablets and Its Pharmacokinetic Evaluation in Rats
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12:30 PM – 1:30 PM
ET
(M1230-01-06) Generic Long-Acting Injectable Product Availability and Approval Standards
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12:30 PM – 1:30 PM
ET
(M1230-03-13) A Heat-Shielded Abuse Deterrent Formulation
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12:30 PM – 1:30 PM
ET
(M1230-03-15) Vacuum Compression Molding as a Novel Technique for the Fabrication of Polymeric Microneedles
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12:30 PM – 1:30 PM
ET
(M1230-03-16) Nose to Brain Delivery of Donepezil after the Administration of HPMC-Me-β-CD-PEG400 Based Nasal Films in C57BL/6J Mice
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12:30 PM – 1:30 PM
ET
(M1230-03-17) Chemosensitization of Liver Cancer Cells Using Synergistic Inhibitor Combination Co-loaded in Docosahexaenoic Acid Based Self-Nanoemulsifying System
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12:30 PM – 1:30 PM
ET
(M1230-03-18) Using Targeted Lipid Nanoparticles to Deliver Chemotherapy to Pancreatic Cancer
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12:30 PM – 1:30 PM
ET
(M1230-04-19) Dysphagia Prevalence and Pollution
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12:30 PM – 1:30 PM
ET
(M1230-04-20) Development of an In Vitro Release Method for Mechlorethamine Hydrochloride Topical Gel
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12:30 PM – 1:30 PM
ET
(M1230-04-22) Food Effect Risk Assessment in Preformulation Stage Using Material Sparing µFLUX Methodology
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12:30 PM – 1:30 PM
ET
(M1230-04-23) Formulation Design, Characterisation and In Vivo Performance of Self-Emulsifying Drug Delivery Systems (SEDDS) for a BSC Class II NCE
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12:30 PM – 1:30 PM
ET
(M1230-04-24) Comparison of Mucociliary Clearance Rates of Bioadhesive Gels, Powders and Spray-Dried Polymeric Microparticles
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12:30 PM – 1:30 PM
ET
(M1230-06-31) Development and Validation of a Stability Indicating UPLC-DAD Method For The Simultaneous Determination of Praziquantel and Ivermectin In 57/0.18 mg Pharmaceutical Tablets and Dissolution Samples.
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12:30 PM – 1:30 PM
ET
(M1230-06-32) Improve NTA Measurement Repeatability with Correct Diluent
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12:30 PM – 1:30 PM
ET
(M1230-06-33) 4D Printed Temperature Responsive Drug-Eluting Biodegradable Stent for Coronary Artery Disease
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12:30 PM – 1:30 PM
ET
(M1230-06-34) Solid Form Screening and Crystallization Process Development of a Clinical Phase II API
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12:30 PM – 1:30 PM
ET
(M1230-07-37) Novel Composite Collagen-Hyaluronic Acid-Sodium Alginate Based Scaffolds Crosslinked with Calcium Chloride for Potential Chronic Wound Healing Applications
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12:30 PM – 1:30 PM
ET
(M1230-07-38) Assessing the Interrelationship of Microstructure, Properties, Drug Release Performance, and Preparation Process for Amorphous Solid Dispersions
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12:30 PM – 1:30 PM
ET
(M1230-07-39) Impact of Modulating HPMC Properties on Modified Released Matrix Formulation of a High Dose Drug
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12:30 PM – 1:30 PM
ET
(M1230-07-40) Ultra-deformable Nanocarrier of BRD4 PROTAC and Aurora Kinase B Inhibitor to Target “Undruggable” c-Myc in BRAF Inhibitor-Resistant Melanoma
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12:30 PM – 1:30 PM
ET
(M1230-07-41) Effects of Lipidoid-Polymer Hybrid Nanoparticles on the Biophysical Function and Structure of Pulmonary Surfactant
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12:30 PM – 1:30 PM
ET
(M1230-08-43) A Survey of Biological License Application of Monoclonal Antibodies – Part II: Comparability Approaches for Manufacturing Changes
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12:30 PM – 1:30 PM
ET
(M1230-08-44) Case Study Approach for API Mechanical Properties Evaluation on Oral Solid Dosage Forms Development
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12:30 PM – 1:30 PM
ET
(M1230-08-45) Comparing the Stability-Indicating Parameters for 4 New Salts of Bedaquiline
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12:30 PM – 1:30 PM
ET
(M1230-08-46) Functionality and Properties Influences of Microcrystalline Cellulose on Wet Granular Processability in a Twin Screw Granulation
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12:30 PM – 1:30 PM
ET
(M1230-08-47) Varied Bulk Powder Properties as a Result of Particle Engineering Methods for Micronized API: Implications of Crystal Surface Anisotropy for Materials within Size Specifications
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12:30 PM – 1:30 PM
ET
(M1230-09-49) Combining Acoustic Liquid Handling with the Gyros Immunoassay Platform for Bioanalysis of Therapeutic Antibodies in Small Volume Samples
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12:30 PM – 1:30 PM
ET
(M1230-09-50) Development of a Bridging ECL Method for the Detection of Anti-Drug Antibodies in Human Serum on an Automated System
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12:30 PM – 1:30 PM
ET
(M1230-09-51) Improving Sensitivity and Separation of Multiple Nucleotides Utilizing a Metal Free UHPLC System
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12:30 PM – 1:30 PM
ET
(M1230-09-52) Ranking mAb-excipient Interactions in Biologics Formulations by NMR and Molecular Dynamics
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12:30 PM – 1:30 PM
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(M1230-09-53) Assessment of Alternative Fit-for-Purpose Strategies for Non Affinity-Based LC-MS Quantitation of Target Proteins in Biological Matrices
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12:30 PM – 1:30 PM
ET
(M1230-10-56) A Targeted Approach to Studying DNA Methylation in Individuals with Bipolar Disorder and Suicidal Behavior
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12:30 PM – 1:30 PM
ET
(M1230-10-57) Correlating In Vitro and In Vivo Performance of Low-to-High Drug Load Amorphous Spray-Dry Dispersions
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12:30 PM – 1:30 PM
ET
(M1230-10-58) Evaluation of Niclosamide as a Repurposed Adjuvant for Treatment of Extensively Drug-Resistant Burkholderia cepacia Complex Infections
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12:30 PM – 1:30 PM
ET
(M1230-10-59) Identifying Novel Synthetic Lethal Drug Targets to Overcome Chemotherapy Resistance in Triple Negative Breast Cancer by Genome-Wide CRISPR/Cas9 Screen Paralleled with Transcriptome RNAseq
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12:30 PM – 1:30 PM
ET
(M1230-11-61) Quantitative Liver Function Test for Nonalcoholic Fatty Liver Disease
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12:30 PM – 1:30 PM
ET
(M1230-11-62) Formulation and Taste Assessments in First in Human Studies–Evolving beyond Safety, Tolerability, and Pharmacokinetics
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12:30 PM – 1:30 PM
ET
(M1230-11-63) Single-Dose Pharmacokinetics of Intranasal Amiloride in Healthy Volunteers
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12:30 PM – 1:30 PM
ET
(M1230-11-64) Implementation of Solid Phase Extraction Acid Dissociation (SPEAD) Methodology in Reconciling Drug Tolerance Demands of Immunogenicity
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12:30 PM – 1:30 PM
ET
(M1230-11-65) Anti-inflammatory Effects of Bone-Targeted Angiotensin1-7 Delivery in Adjuvant Arthritic Rat Model
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12:30 PM – 1:30 PM
ET
(M1230-12-67) Spray-Dried Inhaled Solid Dispersion of Amodiaquine for Respiratory Disorders
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12:30 PM – 1:30 PM
ET
(M1230-12-69) Cytotoxicity, Safety and Mammary Tissue Retention of Nanostructured Lipid Carriers Co-encapsulating Paclitaxel and Tributyrin as a Novel Approach for Local Breast Cancer Treatment
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12:30 PM – 1:30 PM
ET
(M1230-12-70) Cyclodextrin Inclusion Complex of Novel Anti-mycobacterial Compound
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12:30 PM – 1:30 PM
ET
(M1230-12-72) Optimizing the Synthesis and Performance of Amorphous Drug-Polymer Salts through Acid-Base Reactions: an X-ray Photoelectron Spectroscopy Study
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12:30 PM – 1:30 PM
ET
(M1230-07-42) Investigating Protein-Excipient Interactions of a Multivalent V
HH
Therapeutic Protein using NMR Spectroscopy
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1:30 PM – 2:30 PM
ET
(M1330-01-02) Preparation and Evaluation of Celecoxib Nanosuspension for Enhancing Its Solubility
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1:30 PM – 2:30 PM
ET
(M1330-01-03) Design and Optimization of Lornoxicam Dispersible Tablets Using Quality by Design Approach
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1:30 PM – 2:30 PM
ET
(M1330-01-04) Injectability for High Concentration Monoclonal Antibody Formulations
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1:30 PM – 2:30 PM
ET
(M1330-01-05) Creation and Utilization of Polymer “Alloys” to Increase Drug Loading and Dissolution Performance of Ivacaftor Amorphous Solid Dispersion
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1:30 PM – 2:30 PM
ET
(M1330-02-07) Ropivacaine Toxicokinetics following Bony and Soft Tissue Administration in Rats and Pigs of a Novel Long-Acting Ropivacaine (CPL-01)
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1:30 PM – 2:30 PM
ET
(M1330-02-08) Understanding the Pharmacometabodynamics of Gefitinib Using Ion Mobility MS Based Metabolomics and Microsampling
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1:30 PM – 2:30 PM
ET
(M1330-02-09) More than the Sum of Its Parts: In Silico Immunogenicity Risk Assessment for Fusion Proteins and Novel Antibody Modalities
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1:30 PM – 2:30 PM
ET
(M1330-02-10) Physiological Based Biopharmaceutics Modeling (PBBM) for pH-dependent DDI Risk Identification and Formulation Selection for a Weak Base Compound
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1:30 PM – 2:30 PM
ET
(M1330-02-11) Artificial Extracellular Matrices as Tools for In Vivo Injectable Formulation Analysis
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1:30 PM – 2:30 PM
ET
(M1330-02-12) PET/CT Imaging of Bleomycin-Induced Murine Pulmonary Fibrosis Using a Radiolabeled PEGylated Functional Upstream Domain Peptide
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1:30 PM – 2:30 PM
ET
(M1330-03-14) Apparent Danazol and Ketoconazole Solubility in the Upper Gastrointestinal Lumen after Administration of a Standard High-Calorie, High-Fat Meal and Its Estimation Using Biorelevant Media
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1:30 PM – 2:30 PM
ET
(M1330-03-15) Control of Drug Release Kinetics from Hot-Melt Extruded Drug/Polycaprolactone Matrices
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1:30 PM – 2:30 PM
ET
(M1330-03-16) pH-Independent Modified Release Matrix Tablet of Weakly Basic Drug Using Acidic Ionizable Polymer
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1:30 PM – 2:30 PM
ET
(M1330-03-17) Alternative Methotrexate Oral Formulation: Enhanced Aqueous Solubility, Bioavailability, Photostability, and Permeability
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1:30 PM – 2:30 PM
ET
(M1330-03-18) Study of the Physiochemical Characteristics of Luteolin for Application in (Trans)Dermal Delivery
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1:30 PM – 2:30 PM
ET
(M1330-04-19) Mechanistic Understanding of the Impact of Ionic Interactions between Drug and Polymer on HPMCAS-Based Amorphous Solid Dispersion Performance
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1:30 PM – 2:30 PM
ET
(M1330-04-20) Tailoring the In Vitro Release of Reparixin-Loaded PLGA Microspheres
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1:30 PM – 2:30 PM
ET
(M1330-04-21) Preparation and Characterization of Poorly Soluble Protein (MET 0226) Liposomal Nanoparticle by High Press Homogenizer
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1:30 PM – 2:30 PM
ET
(M1330-04-22) Controlling the Release of Copper from 3D Printed Calcium Phosphate Scaffolds for Bone Regeneration
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1:30 PM – 2:30 PM
ET
(M1330-04-23) Reversible, Covalent DNA Condensation Approach via Chemical Linkers for Enhanced Gene Delivery
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1:30 PM – 2:30 PM
ET
(M1330-05-25) Internalization and Trafficking Pathway of T-Cell Receptor Mimic Antibodies (TCRm) RL6A in Human Brain Endothelial Cells at the Blood Brain Barrier (BBB)
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1:30 PM – 2:30 PM
ET
(M1330-05-26) The Cationic Antimicrobial Peptide, D-LAK-120A, as a Potential Anti-cancer Therapeutic for Non-small Cell Lung Cancer (NSCLC)
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1:30 PM – 2:30 PM
ET
(M1330-05-27) Geometry Study of Theophylline-Containing SLS Printed Pharmaceutical Tablets
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1:30 PM – 2:30 PM
ET
(M1330-05-28) How a Sintering Enhancer Works as Multifunctional Ingredients for Selective Laser Sintering (SLS) 3D Printing of Pharmaceutical Dosage Forms
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1:30 PM – 2:30 PM
ET
(M1330-05-29) A Listeria-Based Vaccine Targeting Interferon-Stimulated Gene 15 for Renal Cell Carcinoma
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1:30 PM – 2:30 PM
ET
(M1330-06-31) Residual Moisture Influences Virus Stability in a Film Based Dosage Form for Long-Term Stability of Biologics
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1:30 PM – 2:30 PM
ET
(M1330-06-32) Reducing Environmental Bias in Measurements of Plume Geometry for Pressurized Metered-Dose Inhalers (pMDIs)
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1:30 PM – 2:30 PM
ET
(M1330-06-33) Encapsulation of a Common Blend Formulation Using an Automatic Encapsulator: A Study on the Effect of Fill Weights on Weight Variation and Dissolution Behavior
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1:30 PM – 2:30 PM
ET
(M1330-06-34) Significance of Drug Excipient Compatibility Studies in Topical Drug Product Development
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1:30 PM – 2:30 PM
ET
(M1330-06-35) Transformational Conical Mill Screen Design: A Paradigm Shift in Scalable Oral Solid Dosage Powder Size Reduction
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1:30 PM – 2:30 PM
ET
(M1330-07-37) Preparation of Polymeric Albumin Nanoparticles by a One-Step Spray Drying Process
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1:30 PM – 2:30 PM
ET
(M1330-07-38) Comparison of
Hydrangea macrophylla
Flower Extract on the Permeability and Skin Whitening of Ginsenoside Rh1 Based on Cream Formulation
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1:30 PM – 2:30 PM
ET
(M1330-07-39) Photochemical Reaction Mechanism and Kinetics of Nitric Oxide (NO) Release from Solid S-nitrosothiol
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1:30 PM – 2:30 PM
ET
(M1330-07-40) Enteric Coating and Evaluation of Optimized Curcumin-Loaded Nanostructured Lipid Carriers
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1:30 PM – 2:30 PM
ET
(M1330-07-41) Improving Dissolution Performance and Drug Loading of Amorphous Dispersions Through a Hierarchical Particle Approach
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1:30 PM – 2:30 PM
ET
(M1330-07-42) Development of a Theranostic Agent for Potential Diagnosis and Treatment of High-Risk Neuroblastoma in Children
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1:30 PM – 2:30 PM
ET
(M1330-08-43) Fully Automated and DoE-Based Development of a new Oral Solid Dosage Form
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1:30 PM – 2:30 PM
ET
(M1330-08-44) In Vitro Bioequivalence Studies of Generic Dapsone gel 7.5% Using Accelerated Permeation Testing (IVPT) and In Vitro Release Testing (IVRT)
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1:30 PM – 2:30 PM
ET
(M1330-08-45) Quality by Design Approach of Chiral Method Development of Compound E
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1:30 PM – 2:30 PM
ET
(M1330-08-46) Impact of Material Attributes and Critical Process Parameters on Low Dose Powder Filling Using Drum Filler System
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1:30 PM – 2:30 PM
ET
(M1330-08-47) Optimization of HPLC Method for Impurities Determination of Chromophore Molecule to Solve an Anomalous Carry Over Issue
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1:30 PM – 2:30 PM
ET
(M1330-08-48) Quantification and Identity Testing of Soft Gel Capsules using Transmission Raman Spectroscopy
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1:30 PM – 2:30 PM
ET
(M1330-10-55) Do We Emit Drugs through Our Skin?
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1:30 PM – 2:30 PM
ET
(M1330-10-56) Impact of Nebulization on the Physicochemical Properties of Polymeric Nanoparticles for Pulmonary Drug Delivery Applications
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1:30 PM – 2:30 PM
ET
(M1330-10-58) L-carnitine Challenge Test as an Indicator of Sex-Related Predisposition for Adverse Drug Reactions
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1:30 PM – 2:30 PM
ET
(M1330-10-59) Determining the Efficacy and Toxicity Profile of Potential Oral Therapeutics Against SARS-CoV-2 in Mice
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1:30 PM – 2:30 PM
ET
(M1330-11-62) ILDsym
®
, a Quantitative Systems Pharmacology (QSP) Platform, Successfully Simulates the Pathophysiology of Systemic Sclerosis-Interstitial Lung Disease (SSc-ILD) and Inter-patient Variability
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1:30 PM – 2:30 PM
ET
(M1330-11-63) Quantitative Analysis to Discriminate Cutaneous Pharmacokinetic Profiles for Topical Drug Products
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1:30 PM – 2:30 PM
ET
(M1330-11-64) Prediction Accuracy of Allometrically Scaled VLX-1005 Pharmacokinetics
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1:30 PM – 2:30 PM
ET
(M1330-11-65) The Impact of Back Conversion of Acyl Glucuronide Metabolites on the Bioequivalence Studies Submitted in Abbreviated New Drug Applications
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1:30 PM – 2:30 PM
ET
(M1330-12-68) Establishing In Vitro-In Vivo Correlation of Amorphous Solid Dispersions
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1:30 PM – 2:30 PM
ET
(M1330-12-69) Development of Nicotine Dry Powder for Inhalation by Thin-Film Freezing
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1:30 PM – 2:30 PM
ET
(M1330-12-71) Application of Avicel® as Cushioning Agent in MUPS Tablets
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1:30 PM – 2:30 PM
ET
(M1330-04-24) Dual Immunization Against COVID-19 and Influenza Using Fast-Dissolving Buccal Films
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1:30 PM – 2:30 PM
ET
(M1330-12-72) Leveraging Developability Risk Assessment Insights to Identify Key Structural Liabilities and Inform Formulation Strategy for Novel Biologics Modalities
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2:30 PM – 3:30 PM
ET
(M1430-01-02) Impact of Changes in Ophthalmic Emulsion Globule Size Distribution and Viscosity on Tear Film Thickness and Menisci Characteristics
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2:30 PM – 3:30 PM
ET
(M1430-01-03) Topical/Transdermal Strategies for Decontamination of Chemical Warfare Agents and Delivery of Antidotes
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2:30 PM – 3:30 PM
ET
(M1430-01-04) Effect of Plasticizer on the Fabrication and Properties of Hot-Melt Extruded Filaments and Fused Deposition Modelling (FDM) 3D Printed Tablets
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2:30 PM – 3:30 PM
ET
(M1430-01-05) A Systematic Approach to Developing Lipid-Based Drug Delivery Systems (LBDDS) with Fenobrate as Model Drug
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2:30 PM – 3:30 PM
ET
(M1430-01-06) Target New Therapeutics Areas from Aspirin while Using Hot Melt Extrusion as an Enabling Technology
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2:30 PM – 3:30 PM
ET
(M1430-03-13) Investigation of Factors Influencing Drug Release from Controlled Release Hydrophilic Matrix Formulation using Central Composite Design of Experiments
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2:30 PM – 3:30 PM
ET
(M1430-03-14) The Effect of a Clean-Label, Plant-Based Natural Glidant on the Flow Properties of Multiple Model Powders Compared to a Synthetic Glidant
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2:30 PM – 3:30 PM
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(M1430-03-15) 3D Printing of Container Tablets: A New Paradigm for Multi-drug containing Bioactive Self-Nanoemulsifying Drug Delivery Systems (Bio-SNEDDS)
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2:30 PM – 3:30 PM
ET
(M1430-03-16) Palmitoyl Carnitine-Anchored Nanoliposomes for Pancreatic Cancer and Neovasculature-Specific Delivery of Gemcitabine Elaidate
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2:30 PM – 3:30 PM
ET
(M1430-03-17) Design and Development of Folate Decorated Nanoemulsions as the New Pain Nanomedicines
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2:30 PM – 3:30 PM
ET
(M1430-03-18) Super Material-Sparing HME Screening: Simultaneous API Loading and Degradation Predictions
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2:30 PM – 3:30 PM
ET
(M1430-04-19) Facile Dual-Drug Delivery System Based on In Situ Gelling Nanosuspension Formulation of Water-Insoluble Cyclic Peptides
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2:30 PM – 3:30 PM
ET
(M1430-04-20) Development of Novel Topical Formulations of 5-fluorouracil
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2:30 PM – 3:30 PM
ET
(M1430-04-21) Comparison of the Tendency of DC Excipients to Build-Up of Static Electricity
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2:30 PM – 3:30 PM
ET
(M1430-04-22) Determining Critical Parameters that Predict Physical Stability of Amorphous Solid Dispersions
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2:30 PM – 3:30 PM
ET
(M1430-04-23) Evaluating pH and Buffer Effects on (-)- and (+)- Phenserine Chemical Stability
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2:30 PM – 3:30 PM
ET
(M1430-05-25) Dynamic Monitoring of Cancer Cell Growth in Monolayer and 3D Spheroid Cultures by Fluorescence – Correlation with Volume, Cell Viability, and Cellular Protein Measurements
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2:30 PM – 3:30 PM
ET
(M1430-05-27) An Oseltamivir Phosphate Case Study–Use of Mechanistic IVIVE Based PBPK Model for Assessment of Dissolution Safe Space in Adults and Extrapolation to Paediatric Subjects
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2:30 PM – 3:30 PM
ET
(M1430-05-28) The Design and Development of GMC1 Analogues: Targeting the Regulation of Hormonal Receptors in Prostate Cancer Cells
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2:30 PM – 3:30 PM
ET
(M1430-05-29) KY-054, a Novel 4-aryl Chromene Derivative, Enhances Osteoblast Differentiation of Mesenchymal Stem Cells and Shows Osteogenetic Effects in Ovariectomized Rats
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2:30 PM – 3:30 PM
ET
(M1430-06-31) Feasibility of Synchrotron XRD for the Analysis of Mixture Sub-samples
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2:30 PM – 3:30 PM
ET
(M1430-06-32) Transferring Laser Diffraction Particle Size Determination Methods in a Regulated Environment
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2:30 PM – 3:30 PM
ET
(M1430-06-33) Use of PAT Tools in the Development, Monitor and Control of Continuous Manufacturing Processes
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2:30 PM – 3:30 PM
ET
(M1430-06-34) Application of a Population Balance Equation Based Wet Bead Milling Model to Process Design and Scale-Up of a Long Acting Injectable Formulation
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2:30 PM – 3:30 PM
ET
(M1430-06-35) Compatibility of BiTE® (Bispecific T-cell Engager) Drug Product with Manufacturing Materials
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2:30 PM – 3:30 PM
ET
(M1430-07-37) Development of Inhalable Layer-by-Layer Assembled Particles for Small Cell Lung Cancer (SCLC) Treatment
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2:30 PM – 3:30 PM
ET
(M1430-07-38) Capmul-Based Formulations for Topical Delivery of Prodrugs Derived from Methotrexate and 5-Aminolevulinic Acid
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2:30 PM – 3:30 PM
ET
(M1430-07-39) Treatment of Non-Tuberculous Mycobacterial Infections via Spray Dried Tigecycline Dry Powder Aerosols
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2:30 PM – 3:30 PM
ET
(M1430-07-40) Developing Cyclodextrin-Complexed Edaravone – An Inhaled Repurposed Therapy for Idiopathic Pulmonary Fibrosis (IPF)
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2:30 PM – 3:30 PM
ET
(M1430-07-41) The Size of the Unstirred Water Layer as a Function of Diffusion Coefficient
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2:30 PM – 3:30 PM
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(M1430-08-43) Impact of Freezing Rate on Lyophilization Primary Drying Efficiency and Porous Structure: Comparison of Three Measurement Techniques
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2:30 PM – 3:30 PM
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(M1430-08-45) A Systematic Approach to Analytical Method Transfer to Modern UHPLC Instruments
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2:30 PM – 3:30 PM
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(M1430-08-46) The Importance of Design of Experiment Model Selection in Pharmaceutical Product Development - A Case Study of Tablet Compression
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2:30 PM – 3:30 PM
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(M1430-08-47) Accurate Bulk Filling for an Automated and Flexible Drug Substance Manufacture
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2:30 PM – 3:30 PM
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(M1430-09-52) Regulated qPCR Validation and qPCR/ddPCR Cross-Validation
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2:30 PM – 3:30 PM
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(M1430-09-53) Development of a Generic Assay Platform Using Human IgG Light Chain-Specific Antibody Reagents for Concentration Measurement of Antibody Therapeutic in Preclinical Studies
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2:30 PM – 3:30 PM
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(M1430-12-67) Assessing the Effect of Barrier Integrity on Topical and Transdermal Delivery of Diclofenac Sodium Using Physical Enhancement Techniques
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2:30 PM – 3:30 PM
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(M1430-12-69) Development of Multilayer 3D DLP Printed Tablet in One Step Using Automated Rotary Platform
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2:30 PM – 3:30 PM
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(M1430-12-71) Evaluation on Stability of Plant Based Softgels (SeaGel® Technology) versus Gelatin Softgels
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2:30 PM – 3:30 PM
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(M1430-09-50) De Novo Development and Validation of a Flow Cytometry Method for the Detection of Neutralizing Antibodies against Adeno-Associated Virus Serotype 5 (AAV5)
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3:30 PM – 4:30 PM
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(M1530-01-01) Modification of Paclitaxel Nanocrystals by Hydroxypropyl-Beta-Cyclodextrin to Improve Their Release Characteristics, Safety, and Efficacy
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3:30 PM – 4:30 PM
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(M1530-01-03) In Vitro and In Vivo Characterization of Rapidly Dissolving Printlets of Isoniazid Manufactured by SLS 3D Printing
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3:30 PM – 4:30 PM
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(M1530-01-04) Formulation Design of WLBU2 Antimicrobial Peptide Dry Powder for Lung Infections
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3:30 PM – 4:30 PM
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(M1530-01-05) Rapidly Dissolving Polymeric Microneedle Skin Patch of Naloxone for Opioid Overdose Treatment
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3:30 PM – 4:30 PM
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(M1530-03-13) A Strategy to Deliver High Molecular Weight Hyaluronic Acid in Deep Lung: Investigating the Role of Non-immunogenic Surfactant
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3:30 PM – 4:30 PM
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(M1530-03-14) A New Modelling Framework for pH-Sensitive Solid Dispersions Release and Dissolution
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3:30 PM – 4:30 PM
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(M1530-03-15) Drug-Loaded Hydralese™ Poly(Glycerol Sebacate) Urethane Elastomers as Intra-vitreal Microdevices for Ocular Drug Delivery Applications
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3:30 PM – 4:30 PM
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(M1530-03-16) An Assessment of the Gastro-Resistance and Dissolution Rate of Banded and Not-Banded Capsules Coated with an Enteric Coating Film
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3:30 PM – 4:30 PM
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(M1530-03-17) Impacts of Polymer Thermal Degradation on In Vitro Performance of Amorphous Solid Dispersions
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3:30 PM – 4:30 PM
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(M1530-03-18) Impact of Manufacturing Processes of Supersaturation Optimized Ternary Amorphous Solid Dispersions on Solid State and Dissolution Performance
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3:30 PM – 4:30 PM
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(M1530-04-19) Solubility Enhancement and Improved Efficacy of Delamanid Using Cyclodextrin Inclusion Complex
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3:30 PM – 4:30 PM
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(M1530-04-20) Reducing the Pro-Inflammatory and Cytotoxic Side Effects of siRNA- Solid Lipid Nanoparticles by Optimizing Cationic Lipid; DOTAP
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3:30 PM – 4:30 PM
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(M1530-04-21) Assessing In Situ Forming Implants Using Real-Time Imaging
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3:30 PM – 4:30 PM
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(M1530-04-22) Co-formulating Inhalable Powders of Nintedanib, Pirfenidone and Mycophenolic Acid by Thin-Film Freezing Technology
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3:30 PM – 4:30 PM
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(M1530-04-23) Effect of Coacervation Processing Parameters on In Vitro Drug Release from PLGA Microspheres
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3:30 PM – 4:30 PM
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(M1530-04-24) A Brief Review of FDA-Approved New Drug Applications Labeled with Sprinkle Administration
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3:30 PM – 4:30 PM
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(M1530-06-32) Considerations and Impact of Extra-Column Volume on the Analysis and Scaling of a HPLC Separation
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3:30 PM – 4:30 PM
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(M1530-06-33) Dimensional Conformity of Filaments in Hot-Melt Extrusion: Design of Experiment and Process Optimization
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3:30 PM – 4:30 PM
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(M1530-06-34) A New Bitterness Evaluation Index Obtained Using the Taste Sensor for 48 Active Pharmaceutical Ingredients of Pediatric Medicines
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3:30 PM – 4:30 PM
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(M1530-06-35) Paper-Based Fluorophores and Machine Learning: A Versatile Tool for Accurate Identification of Pathogenic Bacteria
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3:30 PM – 4:30 PM
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(M1530-07-37) Bioengineered Smart Microcapsules Containing Natural Killer Cells for the Treatment of Pediatric Cancers
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3:30 PM – 4:30 PM
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(M1530-07-38) Design and Development of Rifampicin Loaded PLGA Nanoparticles for the Prevention of Prosthetic Infections
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3:30 PM – 4:30 PM
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(M1530-07-39) Formulation and Characterization of Gatifloxacin Sesquihydrate Nanostructured Lipid Carriers for Bacterial Conjunctivitis
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3:30 PM – 4:30 PM
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(M1530-07-40) Investigation of Nasal Delivery System of a Prokinetic for the Treatment of Gastroparesis and Other Motility Related Disorders
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3:30 PM – 4:30 PM
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(M1530-07-41) Spray Dried Combination Formulations of Tobramycin and Colistin for Pulmonary Delivery Show Excellent In Vitro Powder Aerosolization
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3:30 PM – 4:30 PM
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(M1530-07-42) Discovery of a Targeted Oral Prodrug for Prostate Cancer Therapy
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3:30 PM – 4:30 PM
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(M1530-08-43) Photo-Oxidation Mechanisms in Liquid Formulations: Thinking beyond Peroxide and Free Radical Induced Degradation
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3:30 PM – 4:30 PM
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(M1530-08-44) At Line Near Infrared Quantification of Alpha – Tocopherol in Process Production of Vitamin E Soft Gelatin Capsule
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3:30 PM – 4:30 PM
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(M1530-08-45) Tracking of Environmental Factors within Qatar’s Ambulance Service Settings: A Pilot Study
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3:30 PM – 4:30 PM
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(M1530-08-47) Air Entrapment during Tablet Compression – Diagnosis and Impact on Tableting Performance Assessed with a Compaction Simulator
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3:30 PM – 4:30 PM
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(M1530-09-50) Design of Total VEGF Assay Provides Simple Data Interpretation of Anti-VEGF Therapeutic Study
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3:30 PM – 4:30 PM
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(M1530-09-51) Validation of IL-1RA and IL-2Rα Biomarker Multiplex ECL Assay to Increase Efficiency and Quality in Supporting Inflammatory Biomarker Studies
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3:30 PM – 4:30 PM
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(M1530-09-52) Validation of a High-Sensitivity Inflammatory Cytokine Panel to Improve Clinical Biomarker Data Utility
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3:30 PM – 4:30 PM
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(M1530-09-53) Development of an Extractionless, Multiplexed Assay for the Direct Detection of miRNAs in Liver Tissue
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3:30 PM – 4:30 PM
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(M1530-10-55) Time-Restricted Feeding Protects Fruit Flies from Anoxic Stress via Up-Regulating Expression of Genes Involved in Fat Metabolism and Oxygen Sensing
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3:30 PM – 4:30 PM
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(M1530-10-56) Leishmania Donovani CYP51 and CYP5122A1 Have Different Biochemical Roles in the Ergosterol Biosynthesis and Display Distinct Inhibition by Antifungal Azole Drugs
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3:30 PM – 4:30 PM
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(M1530-10-57) Assessment of Kynurenic Acid as a Functional Biomarker of Organic Anion Transporter 1/3 (OAT1/3) in Cynomolgus Monkeys
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3:30 PM – 4:30 PM
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(M1530-10-58) Gut Microbial Metabolites Regulate Bidirectional Transport and Intracellular Accumulation of Alzheimer’s disease Amyloid Beta Peptides at the Blood-Brain Barrier Endothelium
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3:30 PM – 4:30 PM
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(M1530-10-59) Discovery of OJT009 as a Novel Inhibitor of Severe Acute Respiratory Syndrome Coronavirus 2
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3:30 PM – 4:30 PM
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(M1530-11-62) Mathematical Modeling to Optimize Dosing Schedules for COVID-19 Vaccines
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3:30 PM – 4:30 PM
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(M1530-11-63) A Population Pharmacokinetic Modeling Approach in Determining the Absolute Bioavailability of Sibeprenlimab, an IgG2 Monoclonal Antibody, from Two Single Ascending Dose Trials in Healthy Subjects
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3:30 PM – 4:30 PM
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(M1530-11-64) Use of Quantitative Systems Toxicology (QST) to Identify Potential Intrinsic Mechanisms of Toxicity
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3:30 PM – 4:30 PM
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(M1530-11-65) Population Pharmacokinetic Modeling of Encapsulated Dexamethasone Sodium Phosphate in Autologous Erythrocyte (EryDex system) in the Treatment of Ataxia Telangiectasia
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3:30 PM – 4:30 PM
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(M1530-12-67) Arginine Coated Self-Emulsifying Nanoglobules for Nasal Delivery of Insulin
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3:30 PM – 4:30 PM
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(M1530-12-68) Novel Selective PPARγ Agonist Locally Delivered with a Bioactive ROS-Scavenging Hydrogel for Periodontitis Treatment
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3:30 PM – 4:30 PM
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(M1530-12-70) Reformulation of Niclosamide into Biofilm Penetrating Nanoparticles to Improve Its Repurposing for the Treatment of Candidiasis
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3:30 PM – 4:30 PM
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(M1530-12-71) Nanoparticle-Based Drug Delivery Approach Increased the Bioavailability and Efficacy of the ART Therapy in Vitro
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3:30 PM – 4:30 PM
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(M1530-09-54) Challenges in Development of Multiplex Biomarker Assays for Neurodegenerative Diseases
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10:30 PM – 11:30 AM
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(M1030-09-53) Development of Rapid LC-MS-MS Method for Therapeutic Monitoring of Plazomicin in Human Plasma
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11:30 PM – 12:30 PM
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(M1130-04-23) Novel Formulation for Simultaneous Decontamination of Chemical Warfare and Delivery of Antidotes for Attenuating Cutaneous Damage Caused by Arsenicals
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