The need to control crop and public health insect pests has been and remains a constant need. Although a number of pest insect control approaches exist, many integrated pest management (IPM) programs have insecticides as a key component. Since the 1970s, improved selectivity (e.g., environment, beneficial insects & pollinators, mammalian toxicology) has been an increasingly important goal. As such, there has been growing interest in insecticide mixtures as a way to address a range of agronomic, pest spectrum, cost, and insect resistance management (IRM) needs. Also, since the 1970’s there have also been notable changes in the sources, rates of introduction, number of classes, and modes of action of new insecticides. Many of these changes have been in response to insect resistance to existing insecticidal compounds. This perspective will review some of the drivers for insecticide mixtures and considerations for sourcing the insecticide components for these mixtures
