Mosquitoes (Culicidae) are ubiquitous flying insects capable of vectoring several important viruses. Mosquito abundance and diversity are influenced by environmental factors like temperature and precipitation and vary within a year and between years. The range and phenology of mosquito species that vector viruses relevant to human health are changing. We sampled mosquito communities in central Oklahoma for four years at thirteen sites, collecting over 24,000 mosquitoes in a total of 30 different species, including several medically relevant species collected in suburban backyards. Community composition differed across the landscape and changed from early season to late season and year to year. This effort to describe mosquito communities in Oklahoma is a first step toward assessing and predicting arbovirus risk, an ongoing and dynamic public health challenge.