Presenting Author
Memorial Sloan-Kettering Cancer Center, Memorial Sloan-Kettering Cancer Center
Born in Taiwan, Ting-Chao (David) Chou received his Ph.D. in Pharmacology from Yale University and completed his Post-Doctoral Fellowship at Johns Hopkins University School of Medicine. He joined Memorial Sloan-Kettering Cancer Center (MSKCC) and became a Member and Professor of Pharmacology at Cornell University Graduate School of Medical Sciences in 1988. He is Honorary Professor of Chinese Academy of Medical Sciences. He retired from MSKCC in 2013 and founded the PD Science LLC (Website: https://www.combosyn.com). Professor Chou is the Member of Johns Hopkins Society of Scholars, induced on April 8, 2019.
In 1976, Dr. Chou introduced the pharmacodynamics (PD)/Biodynamics (BD) General Theory and the Median-Effect Equation of the Mass-Action Law (MAL), as the Unified Theory for BD/PD and Bioinformatics (BI). The new paradigm, the Doctrine of Median, allowed the generation of dose-effect curves by automated computer simulation, forming the basis for Econo-Green biomedical research and development. He co-developed the Combination Index (CI) Theorem, and CompuSyn software. His 1984 theoretical paper with P. Talalay (JHU) introducing the CI theory/method for quantification/simulation of synergism (i.e., CI<1), has been cited 7,536 times in over 1,446 biomedical journals internationally, as of March 9, 2022. The broad-scope of applications of the Chou-Talalay theory/method set a historical record.
Dr. Chou’s published 375 papers have garnered over thirty-eight thousand citations and an h-index of 74. He is inventor/co-inventor of 40 U.S. Patents. Currently, he advocates for MAL based quantitative, cost-effective biomedical R&D/Precision & Translational Medicine, and PD/BD-based reform of basic guidelines and regulations for new drug evaluations.