365 - Developmental Neurotoxicity of Cannabinoids

Session Chair(s)

• Qingcheng Mao

  Univ of Washington School of Pharmacy

• Qing Ma

  University at Buffalo

Recent studies have revealed that cannabis is the second most used drug after alcohol in the US. Evidence shows that cannabis use in adolescents and young adults is associated with adverse neurocognitive reactions. Studies also show that cannabis use by pregnant women has been consistently increasing over time. Cannabis use among these special populations is expected to further increase with recent trends toward legalization of recreational consumption, representing a potential but great public health concern. This symposium is therefore timely with respect to understanding neurotoxicity of cannabinoids in infants and adolescents.

Presentations:

• 8:00 AM – 8:02 AM

  Introduction
• 8:02 AM – 8:27 AM

  Enduring Molecular, Physiological, and BehavioralEeffects of Perinatal Cannabinoids: Mechanisms and Possible Therapeutic Strategies for their Treatment
  

  Speaker: Ken Mackie – Indiana University
• 8:27 AM – 8:52 AM

  Associations Between Prenatal Cannabis Exposure and Psychopathological and Neurological Childhood Outcomes
  

  Speaker: Ryan Bogdan – Washington University in St. Louis
• 8:52 AM – 9:17 AM

  Association between Adolescent Cannabis use and Young-adult Functioning in Three Longitudinal Twin Studies
  

  Speaker: Jonathan Schaefer – University of Minnesota
• 9:17 AM – 9:28 AM

  P-gp and Bcrp Exert Differential Impacts on Maternal and Fetal Exposure to Tetrahydrocannabinol and Its Major Metabolites in Pregnant Mice
  

  Presenting Author: Xin Chen – University of Washington
• 9:28 AM – 9:30 AM

  Conclusion