253 - Glycans in cell biology

Session Chair(s)

• Susan Bellis

  University of Alabama at Birmingham

In this symposium, we will learn about new ways to identify, locate and quantitate the glycans present on different cells under specific conditions. We also will hear how we can dress cells for success through modification of their surface structures. In another section, we will learn how pathogens can recognize and invade cells through specific glycocalyx structures. We also will hear several accounts of how cancer progression can be mediated through overexpression of glycans such as sialic acid and heparan. Apparently, as with people, inhibitions can be dampened by exuberance in cellular dressing.

Who should attend: anyone who is interested in understanding how cells function and interact with their environment through their surface glycan coat and anyone interested in cool new ways to modulate those interactions through carbohydrate chemistry and enzymology.

Presentations:

• 9:15 AM – 9:45 AM

  Hypersialylation of Tumor Cells Promotes Pancreatic Cancer Progression
  

  Presenting Author: Susan Bellis – University of Alabama at Birmingham
• 9:45 AM – 10:15 AM

  SLC3A2 N-glycosylation and alternate evolutionary trajectories for amino acid metabolism
  

  Presenting Author: James Dennis – Lunenfeld Tanenbaum Research Institute
• 10:15 AM – 10:45 AM

  Modeling the mucinous glycocalyx to unravel receptor pattern recognition by influenza A viruses
  

  Presenting Author: Kamil Godula – University of California, San Diego
• 10:45 AM – 11:15 AM

  Cell Surface Glycan Engineering to Examine Receptor Specificities of Influenza and Other Viruses
  

  Presenting Author: Geart-Jan Boons – University of Georgia, Utrecht University