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Basic Science

Basic Science

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(VP010) AN UNSUPERVISED APPROACH TO SYSTEMATICALLY ANALYSIS THE MULTI-OMICS PROFILES ASSOCIATED WITH T2D INSULIN RESISTANCE AND BETA-CELL FUNCTION: AN EU-RHAPSODY STUDY

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(VP070) KETOGENIC DIET REDUCES THE INCIDENCE OF DIABETIC KIDNEY DISEASE AND SLOWS ITS PROGRESSION IN DIABETIC MICE

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(VP072) LOSS OF THIOREDOXIN-INTERACTING PROTEIN (TXNIP) MEDIATES SENESCENCE IN RENAL MESANGIAL CELLS ASSOCIATED WITH HYPERACTIVATION OF AKT AND RAS; A POTENTIAL ADVERSE EFFECT OF THERAPEUTIC TARGETING.

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(VP081) PARACRINE FACTORS REGULATE INTRACELLULAR TRAFFICKING OF GLUCAGON IN PANCREATIC ALPHA CELLS

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(VP092) RENAL TUBULE-SPECIFIC ANGIOTENSINOGEN KNOCKOUT AMELIORATES DIABETIC KIDNEY DISEASE IN TYPE 1 DIABETIC AKITA MICE

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(VP103) SPATIAL TRANSCRIPTOMIC ANALYSIS OF MICROVASCULAR ENDOTHELIAL CELLS IN DIABETIC AND NON-DIABETIC MICE: INSIGHT INTO DIFFERENTIAL RESPONSES TO HYPERGLYCEMIA IN DIFFERENT TARGET ORGANS OF DIABETES

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(VP111) THE DIRECT AMPK-β1 SELECTIVE ACTIVATOR PF-06409577 TARGETS MACROPHAGES TO REDUCE ATHEROSCLEROSIS IN MICE

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(VP115) THE MITOPHAGY RECEPTOR NIX COORDINATES NUCLEAR CALCIUM SIGNALING TO MODULATE THE MUSCLE PHENOTYPE.

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(DCP001) 14-3-3ZETA REGULATES ADIPOGENESIS BY CONTROLLING CHROMATIN ACCESSIBILITY DURING THE EARLY STAGES OF DIFFERENTIATION

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(DCP002) ABCB10, A NOVEL REGULATOR OF METABOLIC INFLAMMATION

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(DCP003) APPLICATION OF A HIGH-THROUGHPUT SCREENING APPROACH TO REPURPOSE PREVIOUSLY-APPROVED DRUGS TO TREAT TYPE 1 DIABETES

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(DCP004) CELLULAR COMMUNICATION NETWORK FACTOR 5 (CCN5) GENE DEFICIENCY CAUSES IMPROVED INSULIN SENSITIVITY AND GLUCOSE TOLERANCE IN DIET-INDUCED OBESITY IN MALE MICE

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(DCP005) CHARACTERIZATION OF HEALTHY AND OBESE ADIPOSE TISSUE REMODELLING BY 3D IMAGING AND SINGLE CELL ANALYSIS

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(DCP006) DIABETES INDUCED CIRCRNA_012164 AND MICRORNA-9-5P EXPRESSION IN CARDIAC ENDOTHELIAL CELLS REGULATE DIABETIC CARDIAC FIBROSIS

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(DCP007) DOES THE T2D-ASSOCIATED HNF1AG319S VARIANT CONFER A METABOLIC ADAPTATION TO FASTING?

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(DCP008) EFFECTS OF ACTOVEGIN ON LIVER AND CARDIAC MITOCHONDRIAL RESPIRATION IN TYPE 1 DIABETES

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(DCP009) EFFECTS OF CIRCULAR RNA ZNF521 ON DIABETIC CARDIAC FIBROSIS

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(DCP010) EXPLORING THE IMPACT OF ANTI-CD3 IMMUNOTHERAPY ON BETA CELL STRESS IN TYPE 1 DIABETES

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(DCP011) GLYCINE RECEPTOR ACTIVITY IN Β CELLS IS DOWNREGULATED IN TYPE 2 DIABETES AND AFTER HIGH GLUCOSE CULTURE

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(DCP012) IMPACT OF MFN2 DELETION ON INSULIN SECRETION AND TRANSIENT MITOCHONDRIAL PERMEABILITY TRANSITION PORE OPENING IN HUMAN ENDOCBH3 BETA CELLS

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(DCP013) KETOGENIC DIET INTERVENTION IMPROVES HEPATIC STEATOSIS BUT NOT GLUCOSE TOLERANCE OR INSULIN SECRETION IN OBESE MICE

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(DCP014) KNOCK-IN OF MCARDINAL AT THE MOUSE GCK LOCUS AS A TOOL TO EXPLORE PANCREATIC BETA CELL HETEROGENEITY

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(DCP016) NRF2 DELETION ATTENUATES LIPID DROPLET ACCUMULATION AND PROXIMAL TUBULAR INJURY VIA INHIBITION CD36 AND FABP4 EXPRESSION IN TYPE 2 DIABETIC (T2D) DB/DB MICE

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(DCP017) PROLACTIN RECEPTOR IS REQUIRED FOR BETA-CELL ADAPTATION TO A HIGH-FAT-DIET IN MULTIPAROUS FEMALE MICE

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(DCP018) SEXUALLY DIMORPHIC EFFECTS OF CCN5/WISP2 OVEREXPRESSION ON HFD-STZ-INDUCED DIABETES AND GLUCOSE INTOLERANCE

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(DCP019) THE LONG CHAIN FATTY ACID RECEPTOR FFA4 STIMULATES INSULIN SECRETION VIA INHIBITIONOF SOMATOSTATIN RELEASE FROM DELTA CELL

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