Assistant Professor of Surgery
The Jackson Laboratory for Genomic Medicine, Hartford Healthcare, UCONN School of Medicine
I am a surgical oncologist with a focus on melanoma, sarcoma, and endocrine tumors and a computational cancer biologist. Tumors are continually evolving collections of cells, characterized by a dynamic interplay among heterogeneous sub-clonal populations that expand and contract under innate and imposed selective pressures. My research couples deep learning imaging techniques with high-resolution molecular assays and matched clinical information to analyze tumors through a framework of evolution. We study the impact of treatment on the dynamics of the tumor ecosystem to elucidate resistance mechanisms and identify potential targets for intervention.