Director and Associate Professor
Cancer Immunotherapeutics Center, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA
Jason J Luke, MD, FACP, is the Director of the Cancer Immunotherapeutics Center at UPMC Hillman Cancer Center and an Associate Professor of Medicine at the University of Pittsburgh. He received his medical degree from Rosalind Franklin University of Medicine and Science in Chicago and trained at Boston University Medical Center, Weill Cornell Medical College, and Memorial Sloan-Kettering Cancer Center in New York City. He held prior tenure-track faculty positions at Harvard Medical School, Dana-Farber Cancer Institute and University of Chicago. He specializes in early phase drug development for solid tumors (particularly novel immunotherapeutics and biomarkers of immunotherapy activity) and the management of cutaneous oncology and melanoma.
He directs the Translational Immuno-Informatics Laboratory which investigates large scale informatic approaches to advance cancer immunotherapy. He is an active internationally recognized translational investigator leveraging work from his laboratory into more than 10 investigator-initiated, NCI CTEP and/or cooperative group clinical trials and acting as the international PI on registration intent industry studies. Some of these studies have changed the standard of care and are cited in the National Comprehensive Cancer Network guidelines. He is currently supported by a DOD award and is co-PI for the HCC UM1 NCI Phase I grant.
He is the recipient of the Melanoma Research Foundation Humanitarian Award, Department of Defense Career Development Award, Paul Calabresi Career Development in Clinical Oncology Award (K12), ASCO Merit Award, and Young Investigator Awards from the Melanoma Research Alliance, Cancer Research Foundation, and Conquer Cancer Foundation of ASCO. He has been a review panel member for the NIH R21 and DOD immunotherapy/melanoma grant review panels and has been the ASCO Scientific Committee chair for Melanoma. He is currently a Senior Editor for Clinical Cancer Research, Melanoma and Skin Cancer Editor for Cancer, and Associate Section Editor for the Journal for Immunotherapy of Cancer.