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Thursday, Mar 23
10:15 AM – 12:00 PM

Endocrine/H & N and Sarcoma Parallel Session
Location:Ballroom A
Moderator: John M. Kane, III, MD – Rowell Park Comprehensive Cancer Center
Moderator: Chee-Chee H. Stucky, MD – Mayo Clinic
Endocrine/Head and Neck
Sarcoma
CME
Thursday, Mar 23
11:06 AM – 11:16 AM

75: T cell Inducible Costimulator (ICOS) blockade increases the efficacy of imatinib in Gastrointestinal Stromal Tumor (GIST)
Location:Ballroom A
Abstract Presenter: Katherine J. Tardy, MD – University of Pennsylvania
First Author: Katherine J. Tardy, MD – University of Pennsylvania
Author: Andrew Tieniber, MD – University of Pennsylvania
Author: Hyunjee V. Kwak, MD – University of Pennsylvania
Author: Kevin Do, BS – University of Pennsylvania
Author: Laura Wang, BS – University of Pennsylvania
Author: Shan Zeng, PhD – University of Pennsylvania
Author: Ferdinando Rossi, PhD – University of Pennsylvania
Author: Ronald P. DeMatteo, MD, FACS (he/him/his) – The Hospital of the University of Pennsylvania
Sarcoma
CME
Thursday, Mar 23
11:16 AM – 11:26 AM

76: Single nuclei RNAseq Reveals Dedifferentiation States from Human ICCs to GIST
Location:Ballroom A
Abstract Presenter: Ashwyn K. Sharma, MD (he/him/his) – UC San Diego
First Author: Ashwyn K. Sharma, MD (he/him/his) – UC San Diego
Author: John Jun, B.S. – UC San Diego
Author: Alexander T. Wenzel, B.S. – UC San Diego
Author: Chih-Min Tang, PhD – UC San Diego
Author: Diwakar Guragain, PhD – UC San Diego
Author: Jill P. Mesirov, PhD – UC San Diego
Author: Jason Sicklick, MD (he/him/his) – Moores Cancer Center | UC San Diego Health
Sarcoma
CME
Thursday, Mar 23
11:26 AM – 11:36 AM

77: Current Patterns of Care and Outcomes for Dermatofibrosarcoma Protuberans: An International Multi-institutional Collaborative
Location:Ballroom A
Abstract Presenter: Leah K. Winer, MD – Division of Surgical Oncology, Fox Chase Cancer Center, Philadelphia, USA
First Author: Leah K. Winer, MD – Division of Surgical Oncology, Fox Chase Cancer Center, Philadelphia, USA
Author: Rita Akumuo, MD – Department of General Surgery, Temple University Hospital, Philadelphia, USA
Author: Elizabeth Handorf, PhD – Division of Biostatistics and Bioinformatics, Fox Chase Cancer Center, Philadelphia, USA
Author: Stephanie Greco, MD, FACS – Division of Surgical Oncology, Fox Chase Cancer Center, Philadelphia, USA
Author: Alex Bartholomew, MD (he/him/his) – Duke University Medical Center
Author: Dan Blazer, III, MD – Duke University Medical Center
Author: Lucie Gabrielova, MD – Department of Surgery, Masaryk Memorial Cancer Institute, Brno, Zluty kopec, Czech Republic
Author: Dagmar A. Krakorova, MD, PhD – Department of Surgery, Masaryk Memorial Cancer Institute, Brno, Zluty kopec, Czech Republic
Author: Ericka Bernard-Bedard, n/a – Division of Surgical Oncology, Ottawa Hospital, Ottawa, Canada
Author: Carolyn Nessim, MD, MSc, FRCSC, FACS (she/her/hers) – The Ottawa Hospital, University of Ottawa, Ottawa Hospital Research Institute
Author: Attila Kollár, MD – Department of Medical Oncology, Inselspital University Hospital Bern, Freiburgstrasse, Switzerland
Author: Radu Olariu, MD PhD – Department of Plastic and Hand Surgery, Inselspital University Hospital Bern, Freiburgstrasse, Switzerland
Author: Romi Cencelj-Arnez, MD – Institute of Oncology
Author: Daphne Hompes, MD, PhD – Department of Surgical Oncology, University Hospitals Leuven, Leuven, Belgium
Author: Sam Ford, n/a – University Hospital Birmingham NHS Foundation Trust
Author: Kenneth Cardona, MD – Winship Cancer Institute, Emory University
Author: Kenji Sato, MD – Department of Musculoskeletal Oncology, National Cancer Center Hospital, Tokyo, Japan
Author: Shintaro Iwata, MD – Department of Musculoskeletal Oncology, National Cancer Center Hospital, Tokyo, Japan
Author: Jeffrey M. Farma, MD – Fox Chase Cancer Center
Author: Anthony M. VIllano, MD – Division of Surgical Oncology, Fox Chase Cancer Center, Philadelphia, USA
Sarcoma
CME
Thursday, Mar 23
11:36 AM – 11:46 AM

78: Detection of Circulating Tumor DNA Predicts Recurrence in Soft Tissue Sarcomas
Location:Ballroom A
Abstract Presenter: Beatrice J. Sun, MD – Stanford University School of Medicine
First Author: Beatrice J. Sun, MD – Stanford University School of Medicine
Author: Amy Y. Li, MD (she/her/hers) – Stanford University School of Medicine
Author: Wilson Alobuia, MD – Stanford University School of Medicine
Author: Dong Hur, BS – Stanford University School of Medicine
Author: Sara K. Daniel, MD (she/her/hers) – Stanford University School of Medicine
Author: Amanda R. Kirane, MD, PhD-c, FACS, FSSO (she/her/hers) – Stanford University
Author: George Poultsides, MD (he/him/his) – Stanford University
Author: Byrne Lee, MD (he/him/his) – Stanford University School of Medicine
Sarcoma
CME
Thursday, Mar 23
11:46 AM – 11:56 AM

79: Dysregulation of Mitochondrial Dynamics via Dynamin-Related Protein 1 Implicated in Dedifferentiated Liposarcoma
Location:Ballroom A
Abstract Presenter: Kyle D. Klingbeil, MD MS – UCLA Health
First Author: Kyle D. Klingbeil, MD MS – UCLA Health
Author: Chris Frias, MS – UCLA Health
Author: Sarah M. Dry, MD – UCLA Health
Author: Joseph G. Crompton, MD PhD – UCLA Health
Author: Fritz C. Eilber, MD – UCLA Health
Author: David B. Shackelford, PhD – UCLA Health
Author: Brian Kadera, MD (he/him/his) – University of California, Los Angeles
Sarcoma
CME
Thursday, Mar 23
12:30 PM – 1:00 PM

Regional Therapies for Soft Tissue Sarcomas
Location:SSO HUB: Melanoma & Sarcoma Zone
HUB Presenter: Dan Blazer, III, MD – Duke University Medical Center
HUB Presenter: Giorgos Karakousis, MD – Hospital of the University of Pennsylvania
Sarcoma
HUB
non-CME
Thursday, Mar 23
2:45 PM – 3:15 PM

Sarcoma Poster Presentations 1
Location:SSO HUB: Melanoma & Sarcoma Zone
HUB Moderator: Neha Goel, MD, FACS – University of Miami
Sarcoma
HUB
non-CME
Thursday, Mar 23
2:46 PM – 2:51 PM

P57: Phosphorylation of IWS1 by AKT Maintains Liposarcoma Tumor Heterogeneity through Preservation of Cancer Stem Cell Phenotypes and Mesenchymal-Epithelial Plasticity
Location:SSO HUB: Melanoma & Sarcoma Zone
Author: Yu Wang, MD/PhD – The Ohio State University, Tongji Hospital, Huazhong University of Science and Technology
Author: Marina Goryunova, MD – The Ohio State University
Author: Hongji Zhang, MD/PhD – West Virginia University
Author: Alessandro La Ferlita, PhD – The Ohio State University
Author: Nipin Sp, PhD – The Ohio State University
Author: Hai Huang, MD/PhD – The Feinstein Institutes
Author: Timothy M. Pawlik, MD, PhD – The Ohio State University Wexner Medical Center
Author: Allan Tsung, MD – University of Virginia
Author: Raphael Pollock, MD PhD – The Ohio State University Wexner Medical Center- Division of Surgical Oncology
Author: Alex C. Kim, MD, PhD – The Ohio State University Wexner Medical Center, The James Cancer Hospital and Solove Research Institute
Poster Presenter: Joal D. Beane, MD – The Ohio State University Wexner Medical Center- Division of Surgical Oncology
Sarcoma
non-CME
Thursday, Mar 23
2:51 PM – 2:56 PM

P58: Immune infiltrate of primary retroperitoneal sarcomas (RPS): a prognostic study
Location:SSO HUB: Melanoma & Sarcoma Zone
Poster Presenter: Dario Callegaro, MD (he/him/his) – Fondazione IRCCS Istituto Nazionale dei Tumori, Milan
Author: Dario Callegaro, MD (he/him/his) – Fondazione IRCCS Istituto Nazionale dei Tumori, Milan
Author: Viviana Vallacchi, PhD – Fondazione IRCCS Istituto Nazionale Tumori
Author: Sara Iadecola, MSc – Fondazione IRCCS Istituto Nazionale dei Tumori
Author: Silvia Brich, PhD – Fondazione IRCCS Istituto Nazionale Tumori
Author: Alessia Bertolotti, MSc – Fondazione IRCCS Istituto Nazionale Tumori
Author: Paola Collini, MD – Fondazione IRCCS Istituto Nazionale Tumori
Author: Federico Passarelli, MSc – Fondazione IRCCS Istituto Nazionale Tumori
Author: Laura Bergamaschi, MSc – Fondazione IRCCS Istituto Nazionale Tumori
Author: Marco Fiore, MD – Fondazione IRCCS Istituto Nazionale dei Tumori
Author: Chiara Colombo, MD – Fondazione IRCCS Istituto Nazionale Tumori
Author: Stefano Radaelli, MD – Fondazione IRCCS Istituto Nazionale Tumori
Author: Roberta Sanfilippo, MD – Fondazione IRCCS Istituto Nazionale Tumori
Author: Silvia Stacchiotti, MD – Fondazione IRCCS Istituto Nazionale dei Tumori
Author: Carlo Morosi, MD – Fondazione IRCCS Istituto Nazionale dei Tumori, Milan
Author: Claudia Sangalli, MD – Fondazione IRCCS Istituto Nazionale dei Tumori, Milan
Author: Rosalba Miceli, PhD – Fondazione IRCCS Istituto Nazionale Tumori
Author: Alessandro Gronchi, MD, FSSO – Fondazione IRCCS Istituto Nazionale dei Tumori
Author: Sandro Pasquali, PhD – Fondazione IRCCS Istituto Nazionale dei Tumori, Milan
Sarcoma
non-CME
Thursday, Mar 23
2:56 PM – 3:01 PM

P59: Comparing complete compartmental resection with tumor only resection of retroperitoneal soft tissue sarcoma using the win ratio
Location:SSO HUB: Melanoma & Sarcoma Zone
Poster Presenter: Amblessed Onuma, MD MS (he/him/his) – The Ohio State University Wexner Medical Center
Author: Amblessed Onuma, MD MS (he/him/his) – The Ohio State University Wexner Medical Center
Author: Melica Nikahd, MS – The Ohio State University Wexner Medical Center- Department of Biomedical Informatics
Author: Diamantis I. Tsilimigras, MD – The Ohio State Wexner Medical Center
Author: Madison Hyer, MS – The Ohio State University Wexner Medical Center- Center for Biostatistics
Author: Samantha Ruff, MD – The Ohio State University Wexner Medical Center, The James Cancer Hospital and Solove Research Institute
Author: Farhan Ilyas, B.S – The Ohio State University College of Medicine
Author: Carlo M. Contreras, MD – The Ohio State University
Author: Valerie Grignol, MD – The Ohio State University
Author: Alex C. Kim, MD, PhD – The Ohio State University Wexner Medical Center, The James Cancer Hospital and Solove Research Institute
Author: Raphael Pollock, MD PhD – The Ohio State University Wexner Medical Center- Division of Surgical Oncology
Author: Timothy M. Pawlik, MD, PhD – The Ohio State University Wexner Medical Center
Author: Joal D. Beane, MD – The Ohio State University Wexner Medical Center- Division of Surgical Oncology
Sarcoma
non-CME
Thursday, Mar 23
3:01 PM – 3:06 PM

P60: Evolution in management of upfront treatment for desmoid tumors
Location:SSO HUB: Melanoma & Sarcoma Zone
Poster Presenter: Alex Bartholomew, MD (he/him/his) – Duke University Medical Center
Author: Alex Bartholomew, MD (he/him/his) – Duke University Medical Center
Author: Kristen E. Rhodin, MD – Duke University Medical Center
Author: Laura Notware, BS – Duke University Medical Center
Author: DIMITRIOS P. MORIS, MD, MSc, PhD – Duke
Author: Elishama Kanu, MD – Duke University Medical Center
Author: Sabran Masoud, MD (he/him/his) – Duke University Medical Center
Author: Thomas C. Howell, MD – Duke University Medical Center
Author: Juliann Kosovec, MD – Duke University Medical Center
Author: Danielle Burner, BS – Duke University Medical Center
Author: Charles Y. Kim, MD – Duke University Medical Center
Author: Alan A. Sag, MD – Duke University Medical Center
Author: Daniel P. Nussbaum, MD – Duke University Medical Center
Author: Sabino Zani, Jr., MD – Duke University Medical Center
Author: Michael E. Lidsky, MD – Duke University
Author: Peter Allen, MD – Duke University Medical Center
Author: Richard F. Riedel, MD – Duke Univesity Medical Center
Author: Dan Blazer, III, MD – Duke University Medical Center
Sarcoma
non-CME
Friday, Mar 24
6:45 AM – 7:45 AM

SpringWorks Industry Forum: The Current State of Desmoid Tumor Management
Location:Room 306
Faculty: James Church, MD
Industry
non-CME
Sarcoma
Friday, Mar 24
11:45 AM – 12:15 PM

The Current Management of Desmoids: So Much More Than Surgery
Location:SSO HUB: Rare/Metastatic Cancers Zone
HUB Presenter: Aimee Crago, MD, PhD (she/her/hers) – Memorial Sloan Kettering Cancer Center
HUB Presenter: Brian Kadera, MD (he/him/his) – University of California, Los Angeles
Sarcoma
HUB
non-CME
Friday, Mar 24
12:30 PM – 1:00 PM

Sarcoma Poster Presentations 2
Location:SSO HUB: Melanoma & Sarcoma Zone
HUB Moderator: Giorgos Karakousis, MD – Hospital of the University of Pennsylvania
Sarcoma
HUB
non-CME
Friday, Mar 24
12:31 PM – 12:36 PM

P61: Outcomes After Resection of Locally Recurrent Retroperitoneal Sarcoma
Location:SSO HUB: Melanoma & Sarcoma Zone
Poster Presenter: Camilla Gasparoli, MD (she/her/hers) – Mayo Clinic
Author: Camilla Gasparoli, MD (she/her/hers) – Mayo Clinic
Author: Justin W. Maroun, MD, PhD – Mayo Clinic
Author: EeeLN Buckarma, MD (she/her/hers) – Mayo Clinic Dept Surgery
Author: Travis E. Grotz, MD – Mayo Clinic
Author: Mark J. Truty, MD, MSc – Mayo Clinic Rochester
Author: Cornelius A. Thiels, DO, MBA – Division of Hepatobiliary and Pancreas Surgery, Mayo Clinic
Sarcoma
non-CME
Friday, Mar 24
12:36 PM – 12:41 PM

P62: Risk Factors for the Development of Early Recurrence in Patients with Primary Retroperitoneal Sarcoma
Location:SSO HUB: Melanoma & Sarcoma Zone
Poster Presenter: Fabio Tirotta, MD – University Hospital Birmingham NHS Foundation Trust
Author: Fabio Tirotta, MD – University Hospital Birmingham NHS Foundation Trust
Author: Michael Fadel, n/a – The Royal Marsden Hospital NHS Foundation Trust
Author: Marco Baia, n/a – University Hospitals Birmingham NHS Foundation Trust
Author: Alessandro Parente, n/a – University Hospital Birmingham NHS Foundation Trust
Author: Valentina Messina, n/a – University Hospitals Birmingham NHS Foundation Trust
Author: Paul Bassett, n/a – Statsconsultancy
Author: Myles J. Smith, FRCS – The Royal Marsden NHS Foundation trust
Author: Max Almond, n/a – University Hospital Birmingham NHS Foundation Trust
Author: Andrew J. Hayes, MBBS FRCS PhD – Royal Marsden Hospital
Author: Anant Desai, n/a – University Hospital Birmingham NHS Foundation Trust
Author: Sam Ford, n/a – University Hospital Birmingham NHS Foundation Trust
Author: Dirk Strauss, n/a – The Royal Marsden Hospital NHS Foundation Trust
Sarcoma
non-CME
Friday, Mar 24
12:41 PM – 12:46 PM

P63: Is there a benefit to radiation and surgery in specific histologic subtypes of retroperitoneal sarcoma?
Location:SSO HUB: Melanoma & Sarcoma Zone
Author: Chee-Chee H. Stucky, MD – Mayo Clinic
Poster Presenter: Anagha Deshpande, MS – Mayo Clinic Alix School of Medicine, Scottsdale, Arizona
Author: Richard Butterfield, M.A. – Department of Biostatistics, Mayo Clinic Arizona
Author: Jonathan Ashman, MD – Mayo Clinic Arizona
Author: Sanjay P. Bagaria, MD – Mayo Clinic
Author: Travis E. Grotz, MD – Mayo Clinic
Author: Cornelius A. Thiels, DO, MBA – Division of Hepatobiliary and Pancreas Surgery, Mayo Clinic
Author: Nabil Wasif, MD, MPH – Mayo Clinic Arizona
Sarcoma
non-CME
Friday, Mar 24
12:46 PM – 12:51 PM

P64: Surgical management of the duodenum during multivisceral resection for retroperitoneal sarcoma (RPS)
Location:SSO HUB: Melanoma & Sarcoma Zone
Poster Presenter: Alessandra Borghi, MD (she/her/hers) – Fondazione IRCCS Istituto Nazionale dei Tumori, Milan
Author: Alessandra Borghi, MD (she/her/hers) – Fondazione IRCCS Istituto Nazionale dei Tumori, Milan
Author: Sandro Pasquali, PhD – Fondazione IRCCS Istituto Nazionale dei Tumori, Milan
Author: Sara Iadecola, MSc – Fondazione IRCCS Istituto Nazionale dei Tumori
Author: Carlo Morosi, MD – Fondazione IRCCS Istituto Nazionale dei Tumori, Milan
Author: Marta Barisella, MD – Fondazione IRCCS Istituto Nazionale dei Tumori, Milan
Author: Claudia Sangalli, MD – Fondazione IRCCS Istituto Nazionale dei Tumori, Milan
Author: Silvia Stacchiotti, MD – Fondazione IRCCS Istituto Nazionale dei Tumori
Author: Roberta Sanfilippo, MD – Fondazione IRCCS Istituto Nazionale Tumori
Author: Marco Fiore, MD – Fondazione IRCCS Istituto Nazionale dei Tumori
Author: Chiara Colombo, MD – Fondazione IRCCS Istituto Nazionale Tumori
Author: Stefano Radaelli, MD – Fondazione IRCCS Istituto Nazionale Tumori
Author: Rosalba Miceli, PhD – Fondazione IRCCS Istituto Nazionale Tumori
Author: Alessandro Gronchi, MD, FSSO – Fondazione IRCCS Istituto Nazionale dei Tumori
Author: Dario Callegaro, MD (he/him/his) – Fondazione IRCCS Istituto Nazionale dei Tumori, Milan
Sarcoma
non-CME
Friday, Mar 24
1:01 PM – 1:13 PM

74: Interim Results of a Phase II Trial of Regional Melphalan via Limb Infusion and Systemic PD1 Blockade in Patients with Extremity Sarcoma
Location:Veterans Memorial Auditorium
Abstract Presenter: Edmund Bartlett, MD – Memorial Sloan Kettering Cancer Center
First Author: Edmund Bartlett, MD – Memorial Sloan Kettering Cancer Center
Author: Sandra D'Angelo, MD – Department of Medicine
Author: Ciara Kelly, MD – Department of Medicine
Author: Evan Rosenbaum, MD – Department of Medicine
Author: Sujana Movva, MD – Department of Medicine
Author: Joseph Erinjeri, MD – Department of Radiology
Author: Charles Fisher, BA – Department of Anesthesia
Author: Samuel Singer, MD – Memorial Sloan Kettering Cancer Center
Author: Cristina Antonescu, MD, PhD – Department of Pathology
Author: Charlotte E. Ariyan, MD, PhD – Memorial Sloan Kettering Cancer Center
Sarcoma
CME
Friday, Mar 24
3:15 PM – 3:45 PM

Surgical Cytoreduction for Metastatic GIST: Who, When, and Why?
Location:SSO HUB: Melanoma & Sarcoma Zone
HUB Presenter: Valerie Grignol, MD – The Ohio State University
Faculty Panel: Jason Sicklick, MD (he/him/his) – Moores Cancer Center | UC San Diego Health
Faculty Panel: Ronald P. DeMatteo, MD, FACS (he/him/his) – The Hospital of the University of Pennsylvania
Faculty Panel: George Demetri, MD (he/him/his) – Dana-Farber Cancer Institute and Harvard Medical School
Sarcoma
HUB
non-CME
Friday, Mar 24
4:30 PM – 5:30 PM

Neoadjuvant Chemotherapy for Soft Tissue Sarcomas: A Patient-Centric Approach
Location:Ballroom A
Moderator: Chandrajit P. Raut, MD, MSc (he/him/his) – Brigham and Women's Hospital Harvard Medical School
Moderator: Carolyn Nessim, MD, MSc, FRCSC, FACS (she/her/hers) – The Ottawa Hospital, University of Ottawa, Ottawa Hospital Research Institute
Sarcoma
CME
Self-Assessment Credit