(626) Rates of Preeclampsia in Subsequent Pregnancies by Race/Ethnicity

To assess whether race/ethnicity impacts rates of preeclampsia amongst pregnant persons with a history of preeclampsia in the previous pregnancy.


Study Design: A retrospective cohort study of two consecutive births in California between 2000-2012 among pregnant persons who had a history of preeclampsia in the index pregnancy. We included singleton, non-anomalous index pregnancies from gestational ages 23-42 weeks. We assessed rates of preeclampsia in the second pregnancy by race/ethnicity, age, BMI, educational attainment and insurance type in chi-squared analysis. We conducted a multivariable logistic regression for repeat cases of preeclampsia by race/ethnicity  adjusting for pre-pregnancy BMI, age, education, and insurance type as potential confounders. Race/Ethnicity  was stratified into patients who identified as Non-Hispanic White,  Non-Hispanic Black, Non-Hispanic Asian, Hispanic, American Indian/American Native (Non-Hispanic), and Other.

Results:

There were 22,096 births that met our inclusion criteria. Of those, 3,908 had preeclampsia in the subsequent pregnancy. Of those with preeclampsia in the second pregnancy, the majority (47%) identified as Hispanic, as did the majority of those without preeclampsia in the second pregnancy (49%). The rest of the populations racial/ethnic makeup were comparable. In our multivariable regression, compared to patients who identified as Non-Hispanic White, there were no significant difference in odds of having preeclampsia again in a subsequent pregnancy by race/ethnicity.


Conclusion:

Among patients who have had preeclampsia in a prior pregnancy, there were no significant differences in odds of having preeclampsia in the subsequent pregnancy by race/ethnicity.