Arterial Interventions and Peripheral Arterial Disease (PAD)
Henry Szeto, DO
Interventional Radiology Resident
Christiana Care
Disclosure(s): No financial relationships to disclose
Assaf Graif, MD (he/him/his)
Attending Physician
Christiana Care
Ankit M. Patel, MD
Attending Physician
Pinnacle Interventional and Physicians, Inc.
Ansar Z. Vance, MD (he/him/his)
Attending Physician
Division of Interventional Radiology, Department of Radiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA
Shawdon Molavi, MD (he/him/his)
Interventional Radiology Independent Resident
Christiana Care
Christopher J. Grilli, DO
Attending Physician
Christiana Care
George Kimbiris, MD, FSIR
Attending Physician
Christiana Care
Daniel A. Leung, MD, FSIR
Professor, Program Director
Christiana Care Health Services
Single-center retrospective review from 2014 - 2020 of 24 consecutive patients (12.5% female, mean age of 80.1 ± 6.4 years) who underwent 28 type II endoleak embolization procedures via a perigraft approach. Endpoints included technical success of perigraft catheterization, technical success of endoleak embolization, reintervention, freedom from AAA growth at follow-up, and adverse events.
Results: Technical success of perigraft catheterization and endoleak embolization were 92.9% and 89.3%, respectively. A combined transarterial and perigraft approach was employed in 30.8% (n=8/26). Ethylene vinyl alcohol copolymer (Onyx) and coils were used in 92.9% and 46.4% cases, respectively. Freedom from AAA growth occurred in 85% (n=17/20). Reintervention occurred in 20.8% (n=5), including 4 repeat perigraft catheterizations. There were 2 SIR minor adverse events including a groin hematoma and dyspnea in a COPD patient. One major adverse event not related to the procedure was recorded involving an admission for atrial fibrillation and urinary retention. During follow up, 1 patient suffered AAA rupture 20 months after the successful index procedure requiring proximal snorkel extension and endograft relining. The 30-day mortality rate was 0. No type Ib endoleaks developed as a result of perigraft catheterization.
Conclusion: The perigraft approach is safe and effective catheterization technique for embolization of type II endoleaks and can replace the translumbar and transcaval approaches in many cases with the advantage of not requiring sac puncture. Like the transcaval approach, it can be performed in a supine patient from a transfemoral approach and can be combined with other approaches if required. The perigraft approach is a useful addition to the armamentarium of catheterization techniques of type II endoleaks.