Percutaneous image-guided cryoablation of extra peritoneal endometriosis: mid term outcomes

Wednesday, March 8, 2023

3:00 PM – 3:09 PM

Location: Phoenix Convention Center, 226ABC

Presenting Author(s)

Francois H. Cornelis, MD, PhD

Professor of Radiology
MSKCC, Weill Cornell Medical College

Disclosure(s): General Electric: Speaking and Teaching (Ongoing); Varian: Speaking and Teaching (Ongoing)

Author/Co-author(s)

MN

Milan Najdawi, MD

Assistant Professor
APHP
LR

LEO RAZAKAMANANTSOA, MD, MSc

Asssitant Professor
APHP
cm

cyril mousseaux, MD

Assistant Professor
APHP
SB

Sofiane Bendifallah, MD, PhD

Associate Professor
APHP
CT

Cyril Touboul, MD, PhD

Professor
APHP
IT

Isabelle Thomassin, MD, PhD

Professor
APHP
MB

Marc Bazot, MD, PhD

Professor
APHP
MB

Matthias Barral, Dr (he/him/his)

Associate Professor Interventional Radiology
Hopital Tenon - Radiology Department

Disclosure(s):

Francois H. Cornelis, MD, PhD: General Electric: Speaking and Teaching (Ongoing); Varian: Speaking and Teaching (Ongoing)

Matthias Barral, Dr: General Electrics: Research Grant for Interventional Radiology ()

Purpose: To evaluate the mid-term outcomes of percutaneous image-guided cryoablation of symptomatic extraperitoneal endometriosis (EE).

Materials and Methods: From 2017 to 2022, cryoablation was performed for EE in a single institution for 42 consecutive patients (median age: 37 years [interquartile range: 33 – 39.5]) on a total of 47 lesions. Patient and procedural characteristics were recorded. Tolerance and efficacy for pain were evaluated.

Results: The mean procedure and hospitalization lengths were 73 minutes [48-94] and 1 day [1-1], respectively; including 67% outpatients. One patient (2%) had a severe adverse event. The median follow-up was 13.5 months [1.1–37.7] after cryoablation. Pain decreased from a median of 8/10 [7-9] on the visual analogue scale to 0/10 [0-1] at the last follow-up (p < 0.0001). The median pain-free survival rates were 93.75% [95% CI, 77.25-98.4] at 6 month, and 82.72% [58.8-93.45] after 12 month, respectively. The median Patient Global Impression of Change score recorded at last follow-up was 1/7 [1 – 2].

Conclusion: Percutaneous cryoablation is safe and effective to significantly reduce pain and obtain local control of extraperitoneal endometriosis.