Insights into Vascular Biology of Endovascular Therapy for Peripheral Arterial Disease

Wednesday, March 8, 2023

3:00 PM – 4:30 PM

Location:Phoenix Convention Center, 232AB

CE: 1.5 Credits

Coordinator(s)

Timothy Clark, MD

Professor
University of Pennsylvania

Disclosure(s): No relevant disclosure to display

Disclosure(s):

Timothy Clark, MD: No relevant disclosure to display

This session will examine the vascular biology of endovascular therapies and devices including vascular injury/remodeling following angioplasty, atherectomy, stenting and vessel modification. Attendees will gain greater insights into the mechanisms of these techniques and technologies to help inform treatment decisions for patients suffering from peripheral arterial disease.

Learning Objectives:

Describe the unique properties of nitinol for stent and vascular device construction, as well as its limitations leading to mechanical fatigue
Define the differences between vascular stents and their biomechanical properties
Describe the vascular biology of in-stent restenosis and the mechanisms of antiproliferative therapeutic devices such as drug-eluting balloons and stents

Presentations:

3:00 PM – 3:15 PM

Fundamental Properties of Nitinol Every Peripheral Interventionist Must Know
Speaker: Timothy Clark, MD – University of Pennsylvania
3:15 PM – 3:30 PM

Open Cell, Closed Cell, Superwoven: Fundamental Differences in PAD Stent Design and Why It Matters
Speaker: Ansar Z. Vance, MD (he/him/his) – Division of Interventional Radiology, Department of Radiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA
3:30 PM – 3:45 PM

Not Your Friends: What Fibroblasts and Vascular Smooth Muscle Cells Do After Your Peripheral Vascular Intervention
Speaker: Shilpa N. Reddy, MD – Division of Interventional Radiology, Department of Radiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA
3:45 PM – 4:00 PM

When the Solution is Drug Elution: A Brief Primer of Agents, Excipients and Where Those Drugs Actually End Up
Speaker: Srini Tummala, MD FSIR FSVM – Florida Vascular Specialists
4:00 PM – 4:15 PM

Why What Works Well in the SFA May Not Work Well (or at All) in the Tibial Arteries
Speaker: Ansar Z. Vance, MD (he/him/his) – Division of Interventional Radiology, Department of Radiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA
4:15 PM – 4:30 PM

Q & A