Professor of Pediatrics
University of Colorado School of Medicine
Aurora, CO
Dr. Nozik is a Professor of Pediatrics in the Section of Pediatric Critical Care. She works clinically in the pediatric ICU and runs a basic research laboratory focused on dysregulated redox signaling in lung diseases and novel approaches to treatments. Her work focuses on an important antioxidant enzyme, extracellular superoxide dismutase (EC-SOD), which is highly expressed in the lung and blood vessels as well as skin and joints under normal conditions and is impaired in diseases characterized by chronic inflammation and fibrosis such as acute lung injury and pulmonary hypertension. She predominantly utilize a series of genetically engineered mouse strains with alterations in EC-SOD expression to test how EC-SOD modulates inflammation and vascular injury in diverse disease models. Ultimately her long-term goal is to provide a foundation for the development of novel diagnostic tools and cell-targeted antioxidant therapies to treat inflammation and fibrosis in life-threatening pediatric lung diseases including acute lung injury and pulmonary hypertension.
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Wednesday, April 26, 2023
3:00 PM – 4:00 PM