Negative pressure wound therapy (NPWT) revolutionized the management of acute and chronic wounds. Today, applications of NPWT are widespread across practice settings with use seen in the treatment of chronic wounds, management of severe soft tissue loss, prevention of surgical site infections and beyond. As advancements in application and innovations in technology continue to emerge, it is important that clinicians are knowledgeable on the latest science and best practice use of NPWT. This session will provide the latest in NPWT and real-world insight on how to optimize NPWT in both in-patient and outpatient settings.