Livestream

Safety and Feasibility of Fecal Microbial Transplantation for Fecal Incontinence in Women

Wednesday, October 4, 2023

2:18 PM – 2:22 PM US PST

Location: Oregon Ballroom

Click to View Image
Image Label: Table 1: Safety Events

Presenting Author(s)

Fabiana M. Kreines, MD (she/her/hers)

Fellow
University of Pennsylvania
Philadelphia, Pennsylvania, United States

PDF

Co-Author(s)

LA

Lily Arya, MD MS

Professor of Obstetrics and Gynecology
University of Pennsylvania
Philadelphia, Pennsylvania, United States
BK

Brendan Kelly, MD

Assistant Professor of Medicine
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania, United States
KB

Kyle Bittinger, PhD

Analytics Core Director of the Microbiome Center
Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, United States
YB

Yelizaveta Borodyanskaya, MPH

Research Coordinator
University of Pennsylvania
Philadelphia, Pennsylvania, United States
UA

Uduak Andy, MD

Associate Professor
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania, United States

Disclosure(s):

Fabiana M. Kreines, MD: No financial relationships to disclose

Lily Arya, MD MS: Urovant sciences: consultant (Ongoing), Consultant/Advisory Board (Ongoing)

Brendan Kelly, MD: No financial relationships to disclose

Kyle Bittinger, PhD: No financial relationships to disclose

Yelizaveta Borodyanskaya, MPH: No financial relationships to disclose

Uduak Andy, MD: No financial relationships to disclose

Fecal incontinence (FI) is a debilitating condition that adversely affects quality of life. Though FI has traditionally been attributed to anal sphincter injury during childbirth, changes to the gut microbiota may be an important contributor. Others have demonstrated that fecal microbial transplantation (FMT) is a viable treatment option for gastrointestinal illnesses such as inflammatory bowel disease and irritable bowel syndrome. This is the first study of which we are aware to investigate the role of FMT in the treatment of FI. Our study demonstrates that FMT for FI is safe and feasible and could be a potentially promising treatment for this very burdensome condition.