PhD Candidate Philipps Universität Marburg Marburg, Hessen, Germany
If you are passionate about chemical modifications of natural polymers, this talk is the right choice. A well-designed scheme starts with an introduction to edible sources of proteins, with a special focus on corn proteins, which will be presented in three different subtitles. First, the structure and chemical modifications of corn protein; the second will be the implementation of corn protein in photodynamic therapy as a drug delivery candidate in 2D and 3D cell culture models; and the third is the functionalization of corn protein for targeted therapy, either for the parenteral or enteral purposes to enhance the delivery of cytotoxic drugs and photosensitizers. The third part will further focus on implementing the chemically modified corn protein in 3-D models ( spheroids and organoids) with particular stress on the pharmacokinetic profile of the orally administered protein. Each title will include several short subtitles and illustrations with supporting figures and graphs corresponding to the collected research data.
Learning Objectives:
Upon completion, participant will be able to list the advantages of corn protein as a cheap and readily available substance in drug delivery
Upon completion, participant will be able to recognize the possibilities of chemical engineering of the surface of corn protein to achieve the desired results
Upon completion, participant will be able to understand the biological aspect of implementing corn protein in cancerous and noncancerous 3D cultural models
Upon completion, participant will be able to correlate the in vitro biological findings with the findings obtained from further animal studies established with corn protein designed as nanoparticles.
