Hamid R. Abbasi, n/a: No financial relationships to disclose
Introduction: Oblique lateral lumbar interbody fusion (OLLIF) is a recent innovation in MI spinal fusion OLLIF is performed with the patient in the prone position and employs an oblique lateral approach that enables the instrumentation to pass through Kambin’s triangle, which is defined as the space between the exiting nerve, the superior border of the caudal vertebra, and the superior articulating process of the inferior facet. While it has long been shown that arthroscopic fusions through Kambin’s triangle are feasible, these procedures have suffered from high complication rates due to nerve damage. To avoid these complications, we have modified the procedure by using electrophysiological monitoring and biplanar fluoroscopy to ensure a safe approach. Unlike other MI approaches to the lumbar spine, OLLIF can safely be employed from T12–S1 and does not require any ostomies.
Material and
Methods: This study is a retrospective case series including 303 OLLIF procedures performed by the same surgeon. Procedures were performed in five Minnesota hospitals. Institutional review board (IRB) exemption was granted by Pearl Pathways IRB on 30 January 2017 (IRB study number 17-TRIS-106). The Clinical Trial registration for this study is registered on clinicaltrials.gov as trial NCT03726190. All patients underwent a full course of conservative therapy before being considered candidates for surgery. Preoperative imaging included magnetic resonance imaging, X-ray of the lumbar spine with flexion and extension. OLLIF is indicated for severe degenerative disc disease, spondylolisthesis, spinal stenosis and disc herniation. Skin to skin surgery time, blood loss, fluoroscopy time, and hospital stay were recorded and entered into a custom database immediately after discharge. Because no suction is used in OLLIF, blood loss was measured by postoperatively weighing sponges and subtracting their dry weight. We also obtained routine CT follow-up imaging to assess fusion and hardware failure at least 300 days after surgery. Images were read by two independent radiologists.
Results: Perioperative outcomes are presented are stratified by the number of surgical levels. For a single-level OLLIF, mean surgery time was 52 ± 18.9 minutes, with a blood loss of 42.2 ± 31.1 mL, 198.8 ± 87.2 seconds of fluoroscopy time and a hospital stay of 2.2 ± 1.7 days. Linear regression shows that controlling for the number of levels, there is no significant impact of BMI on surgery time (OLS coefficient 0.23, 95% CI -0.15 to 0.61) and that each additional level of surgery increases surgery time by 24.9 (95% CI 21.72 to 28.10) minutes.
Conclusion: This study is the first to present outcomes in a large cohort of OLLIF patients. We demonstrate that OLLIF is a safe, efficient and efficacious technique for fusions of the lumbar spine from T12-L1 to L5-S1. In OLLIF, the spine is approached without compromising supportive connective tissue, muscles or osseous structures. This allows for faster surgeries and short hospitalization even in patients with significant disability and obesity. Based on our perioperative, clinical, and radiographic data we propose that OLLIF should be considered a preferred option for fusions of the lumbar spine.