Panel Discussion: Balancing Ischemic and Bleeding Risk with Antiplatelet Therapy – Personalizing Treatment to Optimize Outcomes

Saturday, February 25, 2023

7:40 PM – 7:55 PM ET

Panel Moderator(s)

David J. Cohen, MD, FSCAI

Director of Clinical and Outcomes Research
Cardiovascular Research Foundation
New York, New York, United States

Disclosure(s): Abbott Inc: Consultant (Ongoing), Contracted Research (Ongoing), Grant/Research Support (Ongoing); Boston Scientific Corporation: Consultant (Ongoing), Grant/Research Support (Ongoing); Brain-Q, Inc: Grant/Research Support (Ongoing); Corvia Medical: Consultant (Ongoing), Grant/Research Support (Ongoing); Edwards Lifesciences: Consultant (Ongoing), Contracted Research (Ongoing), Grant/Research Support (Ongoing); Impulse Dynamics: Consultant (Ongoing); I-Rhythm, Inc: Grant/Research Support (Ongoing); Medtronic: Consultant (Ongoing), Grant/Research Support (Ongoing); MyoKardia: Consultant (Ongoing); Philips: Consultant (Ongoing), Grant/Research Support (Ongoing); Zoll Medical: Consultant (Ongoing), Grant/Research Support (Ongoing)
Paul A. Gurbel, MD, FSCAI

Director
Sinai Center for Thrombosis Research and Drug Development
Baltimore, Maryland, United States

Disclosure(s): Werfen: Grant/Research Support (Ongoing)
Neal S. Kleiman, MD, FACC, MSCAI

Medical Director, Cardiac Catheterization Laboratories
Houston Methodist DeBakey Heart and Vascular Center
Houston, Texas, United States

Disclosure(s): Abbott: Consultant (Ongoing); Boston Scientific: Consultant (Ongoing); Edwards Lifesciences: Consultant (Ongoing); Medtronic: Consultant (Ongoing)
Roxana Mehran, MD, FACC, FACP, FCCP, FESC, FAHA, MSCAI

Professor of Medicine (Cardiology), and Population Health Science and Policy; Director of Interventional Cardiovascular Research and Clinical Trials
Icahn School of Medicine at Mount Sinai
New York, New York, United States

Disclosure(s): Abbot, abiomed, alleviant medical, amgen, am-pharma, arena, AstraZeneca, Atricure: Grant/Research Support (Ongoing); Applied Therapeutics, Elixir Medical, Stel, ControlRad (spouse): Stock-privately held company (Ongoing); Bayer, Biosensors, Biotronik, Boston Scientific, Bristol-Myers Squibb, CardiaWave, CeloNova, Chiesi: Grant/Research Support (Ongoing); Cine-Med Research, Ionis Pharmaceuticals, Novartis, Novo Nordisk, Vectura, WebMD: Consultant (Ongoing); Concept Medical, CSL Behring, Cytosorbents, Daiichi Sankyo, Element Science, Faraday, Filterlex Medical, Humacyte, Idorsia Pharmaceuticals, Janssen, Mediasphere, Medtelligence: Grant/Research Support (Ongoing); Medtronic, Novartis, OrbusNeich, Penumbra, PhaseBio, Philips, Pi-Cardia, PLx Pharma, Protembis, RenalPro, RM Global, Shockwave, Vivasure, Zoll: Grant/Research Support (Ongoing); Scientific Advisory Board for AMA, ACC (BOT Member, SC Member CTR Program), SCAI (Women in Innovations Committee Member), JAMA Cardiology Associate Editor; Faculty CRF: Scientific Advisory Board (Ongoing)

Panel Discussant(s)

Massoud Leesar, MD

Professor of Medicine, Section head-Interventional cardiology
UAB
Birmingham, Alabama, United States

No relationships to disclose
Mamas A. Mamas, MD

Professor of Cardiology
Keele University, United Kingdom, England, United Kingdom

Disclosure(s): Abbott Cardiovascular Systems: Research Grant (includes principal investigator, collaborator or consultant and pending grants as well as grants already received) (Ongoing); Daiichi Sankyo, Inc.: Speakers' Bureau (Ongoing); Terumo Interventional Systems Inc.: Clinical Trial Investigator (Terminated), Consultant/Advisory Board (Terminated), Consulting Fees (e.g., advisory boards) (Terminated), Educational Grant (Terminated)
JR

Jennifer Rymer, MD

Interventional cardiologist
Duke, North Carolina, United States

Disclosure(s): Chiesi USA: Consultant/Advisory Board (Ongoing), Contracted Research (Principal Investigators must provide information, even if received by the institution) (Ongoing); idorsia: Contracted Research (Principal Investigators must provide information, even if received by the institution) (Ongoing); Pfizer: Contracted Research (Principal Investigators must provide information, even if received by the institution) (Ongoing)
Evan Shlofmitz, DO

Director of Intravascular Imaging
St. Francis Hospital - The Heart Center
Roslyn, New York, United States

Disclosure(s): Abbott Vascular: Consultant (Ongoing); Acist Medical: Consultant/Advisory Board (Ongoing); Boston Scientific Corporation: Consultant/Advisory Board (Ongoing); Janssen Pharmaceuticals: Consultant/Advisory Board (Ongoing), Speakers' Bureau (Ongoing); Novo Nordisk: Speakers' Bureau (Ongoing); Philips: Consultant/Advisory Board (Ongoing); Xenter Inc: Consultant/Advisory Board (Ongoing)
Pieter C. Smits, PhD, FESC

Director Interventional Cardiology
Maasstad Ziekenhuis
Rotterdam, Netherlands

Disclosure(s): Abbott Vascular: Consulting Fees (e.g., advisory boards) (Ongoing), Grants/Research Support Recipient (Ongoing); Abiomed: Speaker/Honoraria (includes speakers bureau, symposia, and expert witness) (Terminated); Arena Pharmaceuticals: Consulting Fees (e.g., advisory boards) (Terminated); AstraZeneca Pharmaceuticals: Consulting Fees (e.g., advisory boards) (Terminated); Daiichi Sankyo, Inc.: Grants/Research Support Recipient (Terminated); MicroPort Medical: Contracted Research (Principal Investigators must provide information, even if received by the institution) (Ongoing), Grant Recipient (Ongoing), Scientific Research Study Investigator (Ongoing), Speaker/Honoraria (includes speakers bureau, symposia, and expert witness) (Ongoing); SMT: Contracted Research (Principal Investigators must provide information, even if received by the institution) (Ongoing); Terumo Corporation: Speaker/Honoraria (includes speakers bureau, symposia, and expert witness) (Ongoing)
Gregg W. Stone, MD, FACC, MSCAI (he/him/his)

Physician
Mount Sinai
New York, New York, United States

Disclosure(s): Abbott, Abiomed, Bioventrix, Cardiovascular Systems Inc, Phillips, Biosense-Webster, Shockwave, Vascular Dynamics, Pulnovo and V-wave: University Grants/Research Support (Ongoing); Abiomed, CorFlow, Apollo Therapeutics, Cardiomech, Gore, Amgen, Millennia Biopharma: Consultant (Terminated); Ancora, Cagent, Applied Therapeutics, Biostar family of funds, SpectraWave, Orchestra Biomed, Aria, Cardiac Success, Valfix, Xenter: Stockholder/Ownership Interest (excluding diversified mutual funds) (Ongoing); Medtronic, Pulnovo, Infraredx: Speaker/Honoraria (includes speakers bureau, symposia, and expert witness) (Terminated); Valfix, TherOx, Robocath, HeartFlow, Ablative Solutions, Miracor, Neovasc, Ancora, Vectorious, Elucid Bio, Occlutech, Impulse Dynamics, Adona Medical: Consultant (Ongoing)
Yu Ping Tracy Wang, MD MHS MSc

Professor
Duke University/Duke Clinical Research Institute, North Carolina, United States

Disclosure(s): Abbott, St. Jude: Grant/Research Support (Terminated, November 1, 2022); Artivion: Honoraria (Terminated, November 1, 2022), Research Grant (includes principal investigator, collaborator or consultant and pending grants as well as grants already received) (Terminated, November 1, 2022); AstraZeneca Pharmaceuticals: Consultant (Terminated, November 1, 2022), Grant/Research Support (Terminated, November 1, 2022); BMS: Research Grant (includes principal investigator, collaborator or consultant and pending grants as well as grants already received) (Terminated, November 1, 2022); Boston Scientific: Research Grant (includes principal investigator, collaborator or consultant and pending grants as well as grants already received) (Terminated, November 1, 2022); Chiesi USA: Research Grant (includes principal investigator, collaborator or consultant and pending grants as well as grants already received) (Terminated, November 1, 2022); CSL Behring: Consultant (Terminated, November 1, 2022); Novartis Pharmaceuticals: Consultant/Advisory Board (Terminated, November 1, 2022)

Disclosure(s):

David J. Cohen, MD, FSCAI: Abbott Inc: Consultant (Ongoing), Contracted Research (Ongoing), Grant/Research Support (Ongoing); Boston Scientific Corporation: Consultant (Ongoing), Grant/Research Support (Ongoing); Brain-Q, Inc: Grant/Research Support (Ongoing); Corvia Medical: Consultant (Ongoing), Grant/Research Support (Ongoing); Edwards Lifesciences: Consultant (Ongoing), Contracted Research (Ongoing), Grant/Research Support (Ongoing); Impulse Dynamics: Consultant (Ongoing); I-Rhythm, Inc: Grant/Research Support (Ongoing); Medtronic: Consultant (Ongoing), Grant/Research Support (Ongoing); MyoKardia: Consultant (Ongoing); Philips: Consultant (Ongoing), Grant/Research Support (Ongoing); Zoll Medical: Consultant (Ongoing), Grant/Research Support (Ongoing)

Paul A. Gurbel, MD, FSCAI: Werfen: Grant/Research Support (Ongoing)

Neal S. Kleiman, MD, FACC, MSCAI: Abbott: Consultant (Ongoing); Boston Scientific: Consultant (Ongoing); Edwards Lifesciences: Consultant (Ongoing); Medtronic: Consultant (Ongoing)

Roxana Mehran, MD, FACC, FACP, FCCP, FESC, FAHA, MSCAI: Abbot, abiomed, alleviant medical, amgen, am-pharma, arena, AstraZeneca, Atricure: Grant/Research Support (Ongoing); Applied Therapeutics, Elixir Medical, Stel, ControlRad (spouse): Stock-privately held company (Ongoing); Bayer, Biosensors, Biotronik, Boston Scientific, Bristol-Myers Squibb, CardiaWave, CeloNova, Chiesi: Grant/Research Support (Ongoing); Cine-Med Research, Ionis Pharmaceuticals, Novartis, Novo Nordisk, Vectura, WebMD: Consultant (Ongoing); Concept Medical, CSL Behring, Cytosorbents, Daiichi Sankyo, Element Science, Faraday, Filterlex Medical, Humacyte, Idorsia Pharmaceuticals, Janssen, Mediasphere, Medtelligence: Grant/Research Support (Ongoing); Medtronic, Novartis, OrbusNeich, Penumbra, PhaseBio, Philips, Pi-Cardia, PLx Pharma, Protembis, RenalPro, RM Global, Shockwave, Vivasure, Zoll: Grant/Research Support (Ongoing); Scientific Advisory Board for AMA, ACC (BOT Member, SC Member CTR Program), SCAI (Women in Innovations Committee Member), JAMA Cardiology Associate Editor; Faculty CRF: Scientific Advisory Board (Ongoing)

Mamas A. Mamas, MD: Abbott Cardiovascular Systems: Research Grant (includes principal investigator, collaborator or consultant and pending grants as well as grants already received) (Ongoing); Daiichi Sankyo, Inc.: Speakers' Bureau (Ongoing); Terumo Interventional Systems Inc.: Clinical Trial Investigator (Terminated), Consultant/Advisory Board (Terminated), Consulting Fees (e.g., advisory boards) (Terminated), Educational Grant (Terminated)

Jennifer Rymer, MD: Chiesi USA: Consultant/Advisory Board (Ongoing), Contracted Research (Principal Investigators must provide information, even if received by the institution) (Ongoing); idorsia: Contracted Research (Principal Investigators must provide information, even if received by the institution) (Ongoing); Pfizer: Contracted Research (Principal Investigators must provide information, even if received by the institution) (Ongoing)

Evan Shlofmitz, DO: Abbott Vascular: Consultant (Ongoing); Acist Medical: Consultant/Advisory Board (Ongoing); Boston Scientific Corporation: Consultant/Advisory Board (Ongoing); Janssen Pharmaceuticals: Consultant/Advisory Board (Ongoing), Speakers' Bureau (Ongoing); Novo Nordisk: Speakers' Bureau (Ongoing); Philips: Consultant/Advisory Board (Ongoing); Xenter Inc: Consultant/Advisory Board (Ongoing)

Pieter C. Smits, PhD, FESC: Abbott Vascular: Consulting Fees (e.g., advisory boards) (Ongoing), Grants/Research Support Recipient (Ongoing); Abiomed: Speaker/Honoraria (includes speakers bureau, symposia, and expert witness) (Terminated); Arena Pharmaceuticals: Consulting Fees (e.g., advisory boards) (Terminated); AstraZeneca Pharmaceuticals: Consulting Fees (e.g., advisory boards) (Terminated); Daiichi Sankyo, Inc.: Grants/Research Support Recipient (Terminated); MicroPort Medical: Contracted Research (Principal Investigators must provide information, even if received by the institution) (Ongoing), Grant Recipient (Ongoing), Scientific Research Study Investigator (Ongoing), Speaker/Honoraria (includes speakers bureau, symposia, and expert witness) (Ongoing); SMT: Contracted Research (Principal Investigators must provide information, even if received by the institution) (Ongoing); Terumo Corporation: Speaker/Honoraria (includes speakers bureau, symposia, and expert witness) (Ongoing)

Gregg W. Stone, MD, FACC, MSCAI: Abbott, Abiomed, Bioventrix, Cardiovascular Systems Inc, Phillips, Biosense-Webster, Shockwave, Vascular Dynamics, Pulnovo and V-wave: University Grants/Research Support (Ongoing); Abiomed, CorFlow, Apollo Therapeutics, Cardiomech, Gore, Amgen, Millennia Biopharma: Consultant (Terminated); Ancora, Cagent, Applied Therapeutics, Biostar family of funds, SpectraWave, Orchestra Biomed, Aria, Cardiac Success, Valfix, Xenter: Stockholder/Ownership Interest (excluding diversified mutual funds) (Ongoing); Medtronic, Pulnovo, Infraredx: Speaker/Honoraria (includes speakers bureau, symposia, and expert witness) (Terminated); Valfix, TherOx, Robocath, HeartFlow, Ablative Solutions, Miracor, Neovasc, Ancora, Vectorious, Elucid Bio, Occlutech, Impulse Dynamics, Adona Medical: Consultant (Ongoing)

Yu Ping Tracy Wang, MD MHS MSc: Abbott, St. Jude: Grant/Research Support (Terminated, November 1, 2022); Artivion: Honoraria (Terminated, November 1, 2022), Research Grant (includes principal investigator, collaborator or consultant and pending grants as well as grants already received) (Terminated, November 1, 2022); AstraZeneca Pharmaceuticals: Consultant (Terminated, November 1, 2022), Grant/Research Support (Terminated, November 1, 2022); BMS: Research Grant (includes principal investigator, collaborator or consultant and pending grants as well as grants already received) (Terminated, November 1, 2022); Boston Scientific: Research Grant (includes principal investigator, collaborator or consultant and pending grants as well as grants already received) (Terminated, November 1, 2022); Chiesi USA: Research Grant (includes principal investigator, collaborator or consultant and pending grants as well as grants already received) (Terminated, November 1, 2022); CSL Behring: Consultant (Terminated, November 1, 2022); Novartis Pharmaceuticals: Consultant/Advisory Board (Terminated, November 1, 2022)