Moderated Group Q&A with Session Speakers

Friday, April 28, 2023

11:12 AM – 11:25 AM CST

Location: N427A

Moderator(s)

LA

Lenore Lenore Ackerman, MD, PhD (she/her/hers)

Assistant Professor of Urology
University of California, Los Angeles

Speaker(s)

Michael B. Chancellor, MD

Professor of Urology
Beaumont Health
AS

Andrew Schrepf, PhD
Stephen J. Walker, PHD

Wake Forest Institute for Regenerative Medicine

Patients with chronic pelvic pain conditions (CPP) experience poorer quality of life and more severe symptoms, yet available therapeutic approaches are often ineffective as they do not treat the underlying pathology. Studies of CPP disorders would benefit from incorporating broad approaches involving a diversity of urologic and non-urologic disciplines to promote a more comprehensive characterization of patient phenotypes. This Basic Science Symposium (BSS) will bring the latest research advancements in chronic pelvic pain conditions in urology to the world’s largest gathering of national and international, private and academic practice, and physician scientists and researchers at all career stages. Knowledge gained at the BSS is expected to provide important insights into CPP pathophysiology, a foundation for better segmenting patients for future clinical trials, and ultimately translation into improved clinical management of patients with CPP.

Learning Objectives:

Understand diagnostic and treatment problems associated with chronic pelvic pain and co-morbid conditions.
Learn about the latest basic and translational research studies aimed to clarify the mechanisms and molecular players underlying chronic pelvic pain.
Determine the main neural and non-neural signaling pathways and modulatory factors contributing to the pelvic pain and involved in visceral sensation.
Discuss the inflammatory mediators that influence bladder sensation and function and the mechanisms by which inflammatory dysregulation influences bladder pain.
Recognize the variations in molecular signatures associated with bladder pain and dysfunction and how these may potentially serve to phenotype or prognosticate in bladder pain.