Introduction: We aimed to report the complications, readmission, and oncologic outcomes for 751 consecutive Robotic Radical Cystectomies (RARCs) done at a single tertiary center. Methods: Patients who underwent RARC from 2005 to 2022 were identified. Patient’s demographics, complications and oncological outcomes were described. Recurrence-free (RFS), disease specific (DSS) and overall survival (OS) were depicted using the Kaplan Meier method. Logistic and COX regression were used to evaluate variables associated with complications and oncologic outcomes, respectively. Results: 751 consecutive RARCs were included. Median age was 69 years, 74% were males, 79% had intra-corporeal diversion, and 9% received neobladder. Eighty six percent developed complications (43% had high grade complications). pN+, intra-corporeal diversion, neobladder, inpatient and ICU stay were associated with high-grade complications (Table). pT, pN, soft tissue surgical margins, BMI, age and CCI were the main determinants of survival (Table). RFS, DSS and OS were 64%, 74% and 53% at 5 years; 62%, 66% and 34% at 10 years (Figure). Conclusions: Older age, comorbidity and higher disease stage are associated with survival after RARC SOURCE OF Funding: Roswell Park alliance Foundation
