MP24-16: The LURN SI-10 and IPSS similarly quantify improvement following BPH surgery, but the LURN SI-10 also captures symptoms including incontinence and pain during recovery
Introduction: The LURN SI-10 was designed for comprehensive but practical clinical use in the assessment of lower urinary tract symptoms (LUTS). The LURN SI-10 was previously shown to demonstrate convergent validity with the International Prostate Symptom Score (IPSS) at baseline while also identifying other common and bothersome symptoms such as pain and urinary incontinence (UI), but to date the LURN SI-10 has not yet been evaluated in the postoperative setting. We hypothesize that the LURN SI-10 will show similar responses to treatment as the IPSS while also capturing UI and pain. Methods: Clinical variables and responses to LURN SI-10 and IPSS were compared at baseline, 6 weeks, and 3 months postoperatively following BPH surgeries. Proportions of patients reporting pain and UI on LURN SI-10 were compared. Multivariate analysis was performed to determine predictors of improvement. Results: 333 men underwent BPH surgery: 157 underwent Aquablation, 48 Rezum, 33 Urolift, 34 TURP, 54 PVP, and 7 robotic simple prostatectomy. Baseline characteristics were similar across groups, except for prostate volume, which was larger for Aquablation and simple prostatectomy (median 88ml and 160ml, respectively). IPSS and LURN SI-10 scores, as well as respective improvements in bother and quality of life scores, decreased similarly at postoperative timepoints, reflecting expected improvement after surgery (p < 0.001 for all; Figure). However, the LURN SI-10 also detected symptoms including UI and pain during the postoperative period, and these symptoms were associated with higher total LURN SI-10 and IPSS scores (Table; Figure). Conclusions: The LURN SI-10 and IPSS instruments respond similarly after surgery, but the LURN SI-10 has the additional benefit of assessing symptoms that may be important during recovery including UI and pain. SOURCE OF Funding: None
