Session: MP31: Renal Transplantation & Vascular Surgery I
MP31-15: By donor factor Comparison of pre-transplant CT volumetry and renal dynamic scintigraphy in predicting post-transplant renal function in living renal transplant donors
Introduction: Renal dynamic scintigraphy (RDS) is used to evaluate renal function in donors, and the utility of CT volumetry (CTV) has recently been reported. Both techniques can be discordant, and it is not clear which test is more useful in which patients. To evaluated the correlation between predicted renal function by both examination and post-transplant renal function. Patient factors affecting the usefulness of both examinations were evaluated. Methods: Of 117 renal transplant donors who underwent renal transplantation at our institution between April 30, 2008 and April 30, 2022, 113 patients who underwent RDS and CT prior to transplantation were included. Correlation coefficients and regression equations were obtained from post-transplant estimated GFR (eGFR) and pre-transplant residual renal function calculated from RDS and CTV, respectively. The difference between the post-transplant eGFR and the predicted eGFR from each regression equations were obtained for each case, and the examination with smaller difference was defined as the useful test for that case. Multiple logistic regression analysis using factor including age, sex, BMI, serum creatinine, blood pressure, and presence of diabetes mellitus, which are commonly evaluated before transplantation, was performed to determine factors affecting the usefulness of both examinations. Results: The correlation coefficients between pre-transplant residual renal function calculated from RDS and CTV and post-transplant eGFR were 0.742 and 0.794. The median difference between predicted eGFR and post-transplant eGFR obtained from both regression equations was 3.97 and 3.19 ml/min/1.73 m2, and multiple logistic regression analysis showed that CTV was significantly more useful in patients with higher BMI (p < 0.05). Conclusions: Pre-transplant residual renal function calculated from by RDS and CTV were both positively correlated with post-transplant renal function. The results suggest that CTV is more useful than RDS in patients with high BMI. SOURCE OF Funding: No funding is needed for this study.
