MP32-10: The Cancer of the Bladder Risk Assessment (COBRA) Score and Mortality-Survival Relationship in Patients who have undergone Radical Cystectomy in the Turkish Urooncology Association Database
Introduction: The Cancer of the Bladder Risk Assessment (COBRA) Score is observed as a practical and useful method that can be used to predict survival in patients who have undergone radical cystectomy. We also aimed to evaluate survival by using COBRA score in the bladder cancer patient group in our country. Methods: A total of 910 patients who had undergone radical cystectomy were included in the Turkish Urooncology Association database. Patients were classified according to tumor stage and lymph node (TLN) involvement; Mortality rates and survival were analyzed according to both TLN classification and COBRA score. Results: The mean age of the patients was 63.94±9.55 years, of which 450 (49.5%) were male and 460 (50.5%) were female; while 279 (30.7%) had lymph node involvement, 631 (69.3%) did not. Cancer specific mortality and overall mortality rates were found to be significantly higher in patients with lymph node involvement  (p:0.000*, p:0.042*). There is a statistically significant difference between the COBRA scores and the survival rates in terms of cancer specific mortality according to TLN classification (p:0.000; p<0.05). Survival rate of group with pathological T3-T4 Node (+) were significantly lower than the other groups (p < 0.05). Survival rate of group with Conclusions: The COBRA score can be used as a practical prognostic tool in radical cystectomy patients. As the COBRA score increases, the prognosis worsens, and our results are consistent with the first validated study. SOURCE OF Funding: None
