Introduction: Peyronie’s disease (PD) is an acquired penile deformity resulting from pathological scarring in susceptible patients. Despite a myriad of surgical techniques have been described for the treatment of PD, there are no studies describing the long-standing results of such techniques. Our goal is to provide the first very long term results of Yachia’s corporoplasty in the treatment of PD. Methods: Prospective follow-up of patients who went through YC between 2010-2015. Baseline patient characteristics were collected before procedure. Data from an intermediate post-operative follow-up (IFU) period, ranging from 6-12 months, was recorded including complications, erectile dysfunction (ED), penile shortening, residual curvature, hypoesthesia and global success rate of the surgery. On June 2022, patients were reassessed via phone contact to screen for disease recurrence, sexual function and overall satisfaction with the procedure, using modified Erectile Dysfunction Inventory of Treatment Satisfaction and International Index of Erectile Function with 5 questions. Global success rate was defined as the percentage of patients reporting to be more satisfied and very satisfied at VLFU. Results: After exclusion of 6 cases, 21 patients were include in tha analysis. Patients had a median age of 59 years. Dorsal penile curvatures were most frequent (71.4%). Curvature was 60º or greater in 38,1% of patients. 14.3% of patients were using PDE5i. There were 3 minor post-operative complications At IFU the global success was 91% at IFU. The median very long-term follow-up (VLFU) time was 120 month. By then 47.6% of patients had at least mild to moderate ED and 23.8% were using PDE5i to treat ED. 19% patients report persistence of penile curvature, 47.6% said the curvature was reduced and 33.3% of patients answered the curvature was totally corrected. Penile shortening was reported in 85% cases and glans hypoesthesia in 42.9%. A satisfactory erection was claimed to be achieved by 71.4% of patients. Overall, a global success rate of 76.2% was observed. When asked, 71.4% of patients would repeat the procedure if they went back on time and 76.2% would recommend the procedure to a friend having the same disease. On sub analysis of patients with a curvature below 60º and equal/above 60º, only 25% of patients with a curvature of 60º or greater were satisfied with their sexual performance, opposed to 76.9% of those with a curvature below 60º (p=0.02). The same difference was observed when asked about procedure repetition (50% vs 84.6% said yes) (p=0.088) and if they would recommend the procedure to a friend (50% vs 92.3%) (p=0.027). Conclusions: To our knowledge this is the first report of a very long-term follow-up after YC. The global success rate at VLFU was 76.2% corresponding to a 16% decrease compared to initial follow-up. The finding of a statistically significant lower overall satisfaction of patients with baseline curvature greater than 60º corroborate the principle that for greater curvature disease the tunical lengthening procedures with grafts may be strongly considered even with theoretically more side effects associated. SOURCE OF Funding: None
