Session: MP13: Benign Prostatic Hyperplasia: Surgical Therapy & New Technology I
MP13-10: Perioperative and Functional Outcomes of Greenlight 180-W Photovaporization in Large (>80 cc) Prostates: an Analysis from 7 Centers in the International Global Greenlight Group
Introduction: GreenLight photoselective vaporization of the prostate (PVP) has gained widespread adoption as an option to traditional transurethral resection of the prostate. However, prior reports expressed concern with the use of PVP in large prostates. The aim of this study was to investigate the adjusted outcomes of Greenlight PVP in men with larger prostates (=80 cc) from the largest international experience Methods: Data were obtained from the Global Greenlight Group which pools data from 7 high volume centers. Men with established benign prostatic hyperplasia who underwent GreenLight PVP using the XPS-180W system between 2011-2019 were eligible and assigned into two groups based on their prostate size (=80cc and <80cc). 11 functional and perioperative covariates were collected. Analyses were adjusted for patient age and presence of median lobe Results: 3,426 men met the inclusion criteria. 34.6% (n=1,187) patients had a large prostate size. Baseline age and prostate volume were significantly different between the groups. The magnitude of absolute improvement in unadjusted international prostate symptom score was significantly greater in the large (=80cc) prostate group at 12 months, with an absolute change of 19.17 points (95% CI: 18.46 – 19.88; Figure 1, p <0.01). There was also a significant drop in PVR at both 6- (p = 0.007) and 12-months (p = 0.005). There were no significant differences in transfusion (p = 0.42), hematuria (p = 0.80), or 30-day readmission rates (p = 0.28) Conclusions: Our results from >3000 patients suggest Greenlight PVP-180W is a safe and effective alternative for patients with prostate sizes =80 cc, with outcomes relatively independent from prostate size SOURCE OF Funding: N/A
