Introduction: The Senhance® robotic system (Asensus Surgical Inc, USA) is a new laparoscopy-based robotic platform which has been increasingly used. Currently, there are limited papers discussing the application of Senhance radical prostatectomy (SRP). Here, we compared the SRP learning curve, short-term surgical outcomes and cost analysis with the da Vinci RP (DRP) cases Methods: From Aug 2019 to April 2022, 65 cases of SRP were performed in National Taiwan University Hospital Yunlin branch. We compared peri-operative data with a prospectively collected 60 cases DRP cohort and a retrospectively collected cohort of initial 60 DRP cases enrolled from the National Taiwan University Hospital. Inclusion criteria was patients with biopsy confirmed prostate cancer, American Association of Anesthesiologists Score?3 and without evidence of metastasis. Results: The operative and pathological outcomes of the three cohorts are shown in Table 1. The SRP showed non-inferior results in positive margin rate, blood loss and operative time(OT) than the DRP. We used simple OT to analyze the learning curve. Figure 1-A, 1-B and 1-C represents the OT of experienced LRP-SRP surgeon, LRP-naive SRP surgeons and DRP surgeon respectively. The OT curve showed a much quicker downward trend in the experienced LRP-SRP and DRP surgeons than LRP-naive SRP surgeons. Median cost for each SRP in our hospital was $4170, which was lower than $7675 in the DRP. Conclusions: Safety and short-term outcomes are comparable between SRP and DRP. For experienced laparoscopic RP surgeon, using Senhance system to perform RP is rather straightforward. With a more affordable price as its biggest advantage, Senhance system may serve as a safe and effective alternative for robotic RP. SOURCE OF Funding: Nil
