ADS 26 - Analysis of National Healthcare Safety Network Antimicrobial Use of Tennessee 2019–2022

Monday, June 26, 2023

11:15 AM – 12:15 PM

Presenter(s)

Cari Simmons, MSN, RN, CIC (she/her/hers)

Infection Prevention Specialist 2
Tennessee Department of Public Health
Portland, Tennessee, United States

Co-Author(s)

Dipen M. Patel, MBBS, MPH (he/him/his)

Epidemiologist
Tennessee Department of Public Health
Nashville, Tennessee, United States
CA

Cullen Adre, PharmD (he/him/his)

Pharmacist
Tennessee Department of Public Health, United States
CW

Callyn Wren, PharmD (she/her/hers)

Pharmacist
Tennessee Department of Public Health, United States
Christopher Evans, PharmD (he/him/his)

Pharmacist
Tennessee Department of Health
Nashville, Tennessee, United States

Disclosure(s):

Dipen M. Patel, MBBS, MPH: No financial relationships to disclose

Cullen Adre, PharmD: No financial relationships to disclose

Callyn Wren, PharmD: No financial relationships to disclose

Cari Simmons, MSN, RN, CIC: No financial relationships to disclose

Christopher Evans, PharmD: No financial relationships to disclose

Background: The National Healthcare Safety Network (NHSN) Antimicrobial Use (AU) Option allows antimicrobial stewardship programs to track, analyze, and report AU trends. The Tennessee Healthcare-Associated Infections and Antimicrobial Resistance (HAI/AR) Program uses the NHSN AU Option to calculate facilities’ AU rates and aggregate them at state and regional levels. In 2018, Tennessee began requiring all acute care hospitals to report into the NHSN’s AU Option in a phased approach. These data analyze the current patterns of antimicrobial use among facilities across Tennessee.

Methods: The Tennessee HAI/AR program aggregated monthly NHSN AU Option data to describe statewide usage of antimicrobial agents from January 2019–December 2022. AU rates were calculated as Antimicrobial Days of Therapy (DOT) per 1000 Days Present (DP) for facilities. We used these data to identify the most used antimicrobial drugs across the state facilities. Descriptive statistics were calculated using SAS Version 9.4.

Results: By 2022, 61 facilities reported at least one month of AU data into NHSN. From 2019 to 2022, the AU rate increased from 594 to 600 DOT/1000 DP (p < 0.0001). Most facilities (n=22) were in the 101-250 bed size category with an AU rate of 602.66 DOT/1000 DP. The AU rate varied between regions with the highest in West TN at 730 DOT/1000 DP compared to the Southeast at 499 DOT/1000 DP. Vancomycin, ceftriaxone and piperacillin/tazobactam were the most used antimicrobials at 311, 302, 240 DOT/1000 DP, respectively.

Conclusions: The number of TN facilities submitting AU data into NHSN has increased since 2019. We did observe significant variation in AU rates among the different regions in TN. The HAI/AR program identifies facilities with high AU and areas for potential interventions to improve AU in TN. This analysis shows how state HAI/AR programs can access and leverage NHSN AU Option data to replicate in their respective jurisdictions.

Learning Objectives:

Assess statewide antibiotic use data from the National Healthcare Safety Network's Antibiotic Use Option.
Track, analyze and report antibiotic use trends using NHSN data.
Show how state HAI/AR programs can access and leverage NHSN AU Option data and replicate in their respective jurisdictions.