Abstract: Resistance monitoring is an important component of vector management; however, the link between detected resistance levels and operational control failures is unclear. This link is critically important for sustaining the efficacy of mosquito control practices in the United States and globally, yet it is difficult to address. In addition, the lack of active ingredients available for operational mosquito control underscores the urgency of developing strategies for resistance management within integrated mosquito control programs. In this presentation, we highlight key questions that must be addressed in order to understand linkages between resistance status and control outcomes. We will present ideas on frequency and spatial scales for monitoring risk. In addition, we will discuss potential field-based methods to determine how different resistance levels (low, moderate, high) impact mosquito control outcomes, what we can learn from agricultural pest control, and what additional information is needed to understand the link between mosquito resistance monitoring and management.