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Assistant Professor
Icahn School of Medicine at Mount Sinai
The focus of my research is to understand the mechanisms through which systemic metabolic abnormalities increase breast cancer growth and metastases. Specifically, my work examines the role of metabolic abnormalities associated with obesity and type 2 diabetes, including hyperinsulinemia and dyslipidemia, on cancer progression I have studied how insulin and IGF-1 signaling promote breast cancer and how inhibiting this signaling affects whole body metabolism and cancer progression in pre-clinical animal studies. My recent work has focused on the role of systemic lipid abnormalities on breast cancer growth and metastases. My clinical practice is a dedicated OncoEndocrinology clinic, where I treat the endocrine complications of oncology therapies primarily metabolic and autoimmune endocrine effects of cancer therapies. Therefore, through my research and clinical practice I aim to improve uncover novel mechanisms linking systemic metabolic disorders to breast cancer progression in order to identify novel treatment options for these patients.