Syndromes/Craniofacial Anomalies
Ridila Khan, DDS
Pediatric Dental Resident
University of Michigan, Ann Arbor, MI
University of Michigan
Ann Arbor, Michigan, United States
James R. Boynton, DDS, MS
Clinical Professor, Pediatric Dentistry Division Head and Graduate Program Director
University of Michigan Dental School, Ann Arbor, MI
Ann Arbor, Michigan, United States
Rodney J. Vergotine, BChD, MSc, FAAPD, FABPD, FIADT
Clinical Associate Professor of Dentistry
University of Michigan School of Dentistry, Ann Arbor, MI
Ann Arbor, Michigan, United States
Pierre Robin Sequence (PRS) and Stickler syndrome are two rare genetic conditions that can have notable effects on an individual’s physical and facial development. PRS is characterized by a triad of clinical issues, which include micrognathia, glossoptosis, and upper airway obstruction. Feeding and respiratory issues, as well as dental issues like malocclusion and poor oral hygiene, may result from this. Cleft palate is frequently observed in individuals with PRS, but is not a requirement for diagnosis. PRS can be isolated or can occur as a larger syndrome, such as Stickler syndrome. Stickler syndrome is a disorder that affects the connective tissues in the body and is characterized by abnormalities of the head and face, eyes, ears, and skeleton. Enamel hypoplasia and other dental abnormalities may also be present in individuals with this condition.Â
Both PRS and Stickler syndrome can be treated with a range of medical interventions like surgery, speech therapy, and physical therapy. It is imperative for individuals with these conditions and their families to have access to specialized medical care and support services to help in managing the physical and emotional impacts of these conditions. This case study will explore the diagnosis and dental treatment of a 10-year-old patient with Pierre Robin Sequence and Stickler syndrome.