42 Views

OR43 - CANCELLEDEffect of Human Amniotic Versus Platelet-Rich Ribrin Membrane on Bone Healing after Periapical Root-End Surgery: An Ultrasonographic, Randomized Controlled Trial

Thursday, May 4, 2023

1:30 PM – 1:45 PM CT

Location: E353A (Level 3)

Presenter(s)

Saumya Johri, M.D.S.

Resident doctor
King George's Medical University, Uttar Pradesh, India
LUCKNOW, Uttar Pradesh, India

Disclosure(s): No financial relationships to disclose

Co-Author(s)

PV

Promila Verma, M.D.S.

Professor
King George's Medical University, Uttar Pradesh
lucknow, Uttar Pradesh, India

Disclosure information not submitted.
AT

Aseem Prakash Tikku, M.D.S.

Prof
King George's Medical University, Uttar Pradesh
lucknow, Uttar Pradesh, India

Disclosure information not submitted.
RB

Rhythm Bains, M.D.S.

Professor
King George's Medical University, Uttar Pradesh
lucknow, Uttar Pradesh, India

Disclosure information not submitted.
NA

Nitesh Agarwal, N/A

Senior resident
King George's Medical University, Uttar Pradesh
lucknow, Uttar Pradesh, India

Disclosure information not submitted.

Introduction: The use of membrane barriers and bone grafting materials in endodontic surgery promotes healing by regeneration rather than repair by scar tissue. The human amniotic membrane (hAM) has regenerative and therapeutic properties that can support ideal periapical tissue rehabilitation and promote better healing after surgery. The current trial aimed to evaluate the amniotic membrane's healing potential and compare it with platelet-rich fibrin using color doppler ultrasound. Material and methods: The current study is a randomized, double-blinded, parallel-group, single-center study. 34 systematically healthy individuals requiring endodontic surgery and fulfilling the criteria were randomly placed in two groups. Surgical curettage of the bony lesion was performed and filled with hydroxyapatite graft. Amniotic membrane (Group 1) and platelet-rich fibrin membrane (Group 2) were placed over hydroxyapatite graft, covering the bony crypt, and the flap was sutured back. Changes in the lesion's surface area and vascularity were assessed with ultrasound and color doppler. Results and observations: Chi-square analysis, unpaired t-test, and repeated measures ANOVA were employed for analysis. The groups significantly differed in mean vascularity at one month (p < 0.05). The mean surface area had no statistically significant difference between the groups. However, in terms of the percentage change in surface area, a significant difference was found from baseline to six months (p < 0.05).

Conclusion: Amniotic membrane could be a promising biological material to enhance healing after endodontic surgery. Further large-scale trials and histologic studies are warranted.

OR43 - **CANCELLED**Effect of Human Amniotic Versus Platelet-Rich Ribrin Membrane on Bone Healing after Periapical Root-End Surgery: An Ultrasonographic, Randomized Controlled Trial

Presenter(s)

Co-Author(s)

OR43 - CANCELLEDEffect of Human Amniotic Versus Platelet-Rich Ribrin Membrane on Bone Healing after Periapical Root-End Surgery: An Ultrasonographic, Randomized Controlled Trial