SP-32 - Pathogenicity and Outcome of Apical Periodontitis in Type II Diabetic Mellitus Patients

Apical periodontitis (A.P.) is an inflammatory disease resulting from microbial invasion from an infected root canal system. Diabetes mellitus (D.M.) is a chronic metabolic disorder characterized by hyperglycemia due to defects in insulin production, function, or both. Several studies have shown the adverse effect of D.M. on A.P. by a higher number of periapical lesions, larger lesion size, lower success, and the survival rates of endodontically treated teeth in diabetic patients. Moreover, studies that evaluated the pathogenesis of A.P. in diabetic patients have demonstrated an intense inflammatory infiltrate, a higher quantity of bacteria, and showed significant bone resorption. Thus, the presentation will provide basic concepts and classic and current evidence of apical periodontitis and its pathogenicity in patients with D.M.