Developed in partnership with the Depression and Bipolar Support Alliance.
Incorporating the peer perspective upstream in the development and design of research improves validity and ensures that the output is reflective of the people being served. This session provides best practices around peer and family engagement in executing the PCORI MOBILITY study. The aim of MOBILTY is to assess the comparative effectiveness of a healthy lifestyle program (LIFE) or LIFE plus Metformin on weight gain among children and adolescents with bipolar spectrum disorders prescribed second-generation antipsychotics (SGAs) who are overweight or obese. The focus of this PCORI research directly affects clinicians prescribing SGAs to their adolescent patients living with bipolar disorder and has the potential to provide valuable guidance to clinicians considering lifestyle interventions or metformin to mitigate potential weight gain associated with SGAs and offer potential solutions for prescribers and patients.