OC 49 - Procoagulation, Thromboinflammation, Mitochondria

Moderator(s)

• 

  Julia Sandrin Gauer, PhD

  Mautner BHF Career Development Fellow
  Discovery and Translational Science Department
  Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds.
  Leeds, England, United Kingdom
• 

  Fionnuala Ni Ainle, MD, PhD

  Consultant Haematologist
  School of Medicine
  University College Dublin
  Dublin 20, Dublin, Ireland

Presentations:

• 2:45 PM – 3:00 PM

  Procoagulant platelets have a distinct transcriptome that identifies the large GTPase dynamin as a driver in their formation
  

  Presenting Author: Ibrahim Tohidi-Esfahani, BMed FRACP FRCPA – Department of Haematology, University College London Hospitals NHS Foundation Trust, London, UK

  Co-Author: Shane Whittaker – ANZAC Research Institute, University of Sydney

  Co-Author: Christine S M Lee, PhD – ANZAC Research Institute, University of Sydney

  Co-Author: Heather Campbell – ANZAC Research Institute, University of Sydney

  Co-Author: Kaitao Lai – University of Sydney

  Co-Author: Hai Po Helena Liang – ANZAC Research Institute, University of Sydney

  Co-Author: Maaike Kockx – ANZAC Research Institute, University of Sydney

  Co-Author: Mark Larance – Larance Laboratory, Charles Perkins Centre, University of Sydney

  Co-Author: Vivien M. Chen, Phd FRACP FRCPA – ANZAC Research Institute, University of Sydney
• 3:00 PM – 3:15 PM

  Spatio-temporal control of fibrin formation by platelet glycoprotein V
  

  Presenting Author: Sarah Beck, PhD – University Hospital and Rudolf Virchow Center, University of Würzburg

  Co-Author: Patricia Öftering, MSc – University Hospital Würzburg and Rudolf Virchow Center for Integrative and Translational Bioimaging, University of Würzburg, Germany

  Co-Author: Renhao Li, PhD – Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, USA

  Co-Author: Katherina Hemmen – Rudolf Virchow Center, University of Würzburg

  Co-Author: Magdolna Nagy, PhD – Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands

  Co-Author: Yingchun Wang – Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, USA

  Co-Author: Alessandro Zarpellon – Department of Molecular Medicine, Scripps Research, La Jolla, CA, USA

  Co-Author: Michael K. Schuhmann – University Hospital Würzburg

  Co-Author: Guido Stoll – University Hospital Würzburg

  Co-Author: Zaverio Ruggeri – Department of Molecular Medicine, Scripps Research, La Jolla, CA, USA

  Co-Author: Katrin G. Heinze – Rudolf Virchow Center for Integrative and Translational Biomaging University of Würzburg

  Co-Author: Johan Heemskerk – Department of Biochemistry, CARIM, Maastricht University, Maastricht, the Netherlands; Synapse Research Institute Maastricht, The Netherlands

  Co-Author: Wolfram Ruf – Center for Thrombosis and Hemostasis, Johannes Gutenberg University Medical Center

  Co-Author: David Stegner, PhD – University Hospital Würzburg and Rudolf Virchow Center for Integrative and Translational Biomaging University of Würzburg

  Co-Author: Bernhard Nieswandt – Institute of Experimental Biomedicine, University Hospital Würzburg and Rudolf Virchow Center for Integrative and Translational Bioimaging, University of Würzburg
• 3:15 PM – 3:30 PM

  A microfluidic model to study the initiation of venous thrombosis
  

  Presenting Author: Laura J. Mereweather, MSc – Imperial College London

  Co-Author: Joseph van Batenburg-Sherwood – Imperial College London

  Co-Author: Josefin Ahnström, PhD – Imperial College London

  Co-Author: Isabelle I. Salles-Crawley – St George’s University of London

  Co-Author: James TB Crawley – Imperial College London
• 3:30 PM – 3:45 PM

  Platelet-released mitochondria interact with neutrophils, altering their phenotype and merging with the existing mitochondrial network
  

  Presenting Author: Harriet E. Allan, PhD – Blizard Institute, Queen Mary University of London

  Co-Author: Plinio Ferreira – Imperial College London

  Co-Author: Marilena Crescente, PhD – Manchester Metropolitan University

  Co-Author: Paul C. Armstrong, PhD – Queen Mary, University of London

  Co-Author: Timothy D. Warner – Queen Mary, University of London
• 3:45 PM – 4:00 PM

  Mitochondrial ATP generation in stimulated platelets is essential for granule secretion but dispensable for aggregation and procoagulant activity
  

  Presenting Author: Paresh P. Kulkarni, MD, PhD – Institute of Medical Sciences, Banaras Hindu University

  Co-Author: Mohammad Ekhlak – Department of Biochemistry, Institute of Medical Sciences, Banaras Hindu University

  Co-Author: Vijay Sonkar – Department of Molecular and Human Genetics, Institute of Science, Banaras Hindu University

  Co-Author: Debabrata Dash – Department of Biochemistry, Institute of Medical Sciences, Banaras Hindu University