OC 63 - Hemophilia Clinical I

Moderator(s)

• 

  Margareth C. Ozelo, MD, PhD

  Head of Hematology Division, Hemocentro UNICAMP
  Department of Internal Medicine, School of Medical Sciences
  University of Campinas, UNICAMP
  Campinas, Sao Paulo, Brazil
• 

  Renée Brown Frandsen, MSc

  Senior Statistician
  Biostatistics - Rare Disease & Advanced Therapies
  Novo Nordisk A/S, Søborg, Denmark
  Søborg, Hovedstaden, Denmark

Presentations:

• 2:45 PM – 3:00 PM

  Decreased thrombin generation profile is associated with severe bleeding phenotype in hemophilia: data from the Hemophilia in the Netherlands study
  

  Presenting Author: Marieke Verhagen, MD – Department of Hematology, Radboud University Medical Center, Nijmegen, the Netherlands. Hemophilia Treatment Center Nijmegen-Eindhoven-Maastricht, Nijmegen, the Netherlands. Laboratory of hematology, Radboud university medical center, Nijmegen, the Netherlands

  Co-Author: Waander L. van Heerde – Department of Hematology, Radboud university medical center, Nijmegen, The Netherlands. Hemophilia Treatment Center Nijmegen – Eindhoven – Maastricht, The Netherlands. Enzyre BV, Novio Tech Campus, Nijmegen, The Netherlands.

  Co-Author: Johanna G. Bom, van der – Department Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands

  Co-Author: Erik A.M. Beckers – Department of Hematology, Maastricht University Medical Center + and Maastricht University, Maastricht, The Netherlands

  Co-Author: Nicole M.A. Blijlevens – Department of Hematology, Radboud university medical center, Nijmegen, the Netherlands

  Co-Author: Michiel Coppens, MD, PhD – Department of Vascular Medicine, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands

  Co-Author: Samantha C. Gouw, MD, PhD – Amsterdam UMC, University of Amsterdam, Emma Children’s Hospital, Pediatric Hematology, Meibergdreef 9, Amsterdam, Netherlands; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.

  Co-Author: Joop Jansen – Department of Laboratory Medicine, Laboratory of Hematology, Radboud university medical center, Nijmegen, the Netherlands

  Co-Author: Frank W.G. Leebeek, MD, PhD – Erasmus MC, University Medical Center Rotterdam, The Netherlands

  Co-Author: Lize F.D. van Vulpen – Center for Benign Haematology, Thrombosis and Haemostasis, Van Creveldkliniek, University Medical Center Utrecht, Utrecht University, The Netherlands

  Co-Author: Daniëlle Meijer – Department of Laboratory Medicine, Laboratory of Hematology, Radboud university medical center, Nijmegen, the Netherlands

  Co-Author: Saskia E.M. Schols – Department of Hematology, Radboud university medical center, Nijmegen, The Netherlands. Hemophilia Treatment Center Nijmegen – Eindhoven – Maastricht, The Netherlands
• 3:00 PM – 3:15 PM

  Inter-individual FVIII clearance heterogeneity in PWH in the iPATH study – biological determinants and clinical importance.
  

  Presenting Author: Einas Elsheikh, MRCP-UK,FRCPath – Royal College of Surgeons Ireland, St James Hospital, Dublin8

  Co-Author: Michelle Lavin, MD, PhD – National Coagulation Centre, St. James Hospital and Irish Centre for Vascular Biology, School of Pharmacy and Biomolecular Sciences, Royal College of Physicians and Surgeons in Ireland (RCSI)

  Co-Author: Niamh Larkin – St. James's Hospital, Dublin

  Co-Author: Niamh O'Connell, MD – St. James Hospital

  Co-Author: Kevin Ryan – National Coagulation Centre, St James's Hospital, Dublin

  Co-Author: Mary Byrne – National Coagulation Centre, St James's Hospital, Dublin

  Co-Author: Evelyn Singleton – National Coagulation Centre ,St James's Hospital,Dublin8

  Co-Author: Padraic G. Fallon – Trinity College Dublin

  Co-Author: Jill M. Johnsen, MD – University of Washington, Institute for Stem Cell and Regenerative Medicine, Seattle, WA, USA

  Co-Author: Steven W. Pipe, MD – University of Michigan, Ann Arbor, MI, USA

  Co-Author: Peter L. Turecek, PhD, PharmD – Baxalta Innovations GmbH, a Takeda company

  Co-Author: James O'Donnell – Royal College of Surgeons Ireland, St James Hospital , Dublin8
• 3:15 PM – 3:30 PM

  Safety and Efficacy of Recombinant Factor IX Fusion Protein (rIX-FP) in Previously Untreated Patients with Hemophilia B
  

  Presenting Author: Richard Lemons, MD PhD – University of Utah, Department of Pediatrics and Primary Children’s Hospital, Salt Lake City, Utah, United States

  Co-Author: Michael Wang, MD – University of Colorado Denver Hemophilia and Thrombosis Center

  Co-Author: Julie Curtin – The Children’s Hospital at Westmead, New South Wales, Australia

  Co-Author: Angela Huth-Kuehne – Kurpfalzkrankenhaus Heidelberg GmbH, Heidelburg, Germany

  Co-Author: Lynda Mae Lepatan – Perpetual Succour Hospital, Cebu, Philippines

  Co-Author: Christoph Male, MD, MSc – Department of Paediatrics, Medical University of Vienna, Vienna, Austria.

  Co-Author: Flora Peyvandi, MD, PhD (she/her/hers) – Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy

  Co-Author: Mario Von Depka Prondzinski – Werlhof Institute, Hannover, Germany

  Co-Author: William McKeand – CSL Behring, King of Prussia, United States

  Co-Author: Wilfried Seifert – CSL Behring, Marburg, Germany

  Co-Author: Johannes Oldenburg – University Clinic Bonn, Institute of Experimental Haematology and Transfusion Medicine, Bonn, Germany
• 3:30 PM – 3:45 PM

  Little discrepancy of one-stage and chromogenic assays in a large international cohort of patients with non-severe hemophilia A and B (DYNAMO study)
  

  Co-Author: Anne-Fleur Zwagemaker – Pediatric Hematology, Emma Children's Hospital, Amsterdam University Medical Centers, Amsterdam, the Netherlands

  Co-Author: Fabienne Kloosterman – Pediatric Hematology, Emma Children's Hospital, Amsterdam University Medical Centers, Amsterdam, the Netherlands

  Co-Author: Samantha Gouw – Department of Pediatric Hematology, Emma Children’s Hospital, Amsterdam University Medical Centers, location AMC, University of Amsterdam, Amsterdam, the Netherlands; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden University, Leiden, the Netherlands

  Co-Author: Sara Boyce – Department of Haematology, University Hospital Southampton, Southampton, United Kingdom

  Co-Author: Paul Brons – Department of Pediatric Hemato-Oncology, Radboud University Medical Center, Nijmegen, the Netherlands

  Co-Author: Marjon H. Cnossen – Department of Pediatric Hematology, Sophia Children’s Hospital, Erasmus University Medical Center, Erasmus University Rotterdam, Rotterdam, The Netherlands

  Co-Author: Peter W. Collins, MD – Medical School of Cardiff University

  Co-Author: Jeroen Eikenboom – Department of Internal Medicine, Division of Thrombosis and Hemostasis, Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, The Netherlands.

  Co-Author: Charles Hay – University Department of Haematology, Manchester Royal Infirmary

  Co-Author: Shannon Jackson – Adult Bleeding Disorders Program of BC - Adult Division St. Paul's Hospital, Vancouver, British Columbia, Canada

  Co-Author: Marieke J. Kruip – Department of Hematology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands

  Co-Author: Britta Laros-van Gorkom – Department of Hematology, Radboud university medical center, Nijmegen, The Netherlands; Hemophilia Treatment Center Nijmegen-Eindhoven-Maastricht, The Netherlands

  Co-Author: Christoph Male, MD, MSc – Medical University of Vienna, Austria

  Co-Author: Laurens Nieuwenhuizen – Department of Hematology, Máxima Medical Center, Eindhoven, Netherlands; Radboud university medical center, Hemophilia Treatment Center, Nijmegen – Eindhoven – Maastricht, Netherlands

  Co-Author: Susan Shapiro, MD, PhD – Oxford University Hospitals National Health Service Foundation Trust, University of Oxford, and Oxford National Institute for Health Research Biomedical Research Centre

  Co-Author: Karin Fijnvandraat – Department of Pediatric Hematology, Emma Children’s Hospital, Amsterdam University Medical Centers, location AMC, University of Amsterdam, Amsterdam, the Netherlands; Department of Molecular Hematology, Sanquin Research and Landsteiner Laboratory, Amsterdam, The Netherlands

  Presenting Author: Michiel Coppens, MD, PhD – Amsterdam University Medical Centers, Amsterdam, the Netherlands
• 3:45 PM – 4:00 PM

  Cytokine profile of patients with Acquired Hemophilia A (AHA) in a longitudinal study
  

  Presenting Author: Jessica O. Frade-Guanaes, MsC – Hemocentro UNICAMP, Department of Internal Medicine, School of Medical Sciences, University of Campinas

  Co-Author: Ana P. Racanelli – Hemocentro UNICAMP, Department of Internal Medicine, School of Medical Sciences, University of Campinas

  Co-Author: Lucia H. Siqueira – Hemocentro UNICAMP, Department of Internal Medicine, School of Medical Sciences, University of Campinas

  Co-Author: Carolina Costa-Lima – Hemocentro UNICAMP, Department of Internal Medicine, School of Medical Sciences, University of Campinas

  Co-Author: Samuel S. Medina – Hemocentro UNICAMP, Department of Internal Medicine, School of Medical Sciences, University of Campinas

  Co-Author: Nívia M. Foschi – Hemocentro UNICAMP, Department of Internal Medicine, School of Medical Sciences, University of Campinas

  Co-Author: Luiz G. R. De Lima – Hemocentro UNICAMP, Department of Internal Medicine, School of Medical Sciences, University of Campinas

  Co-Author: Ana P. Francisco – Hemocentro UNICAMP, Department of Internal Medicine, School of Medical Sciences, University of Campinas

  Co-Author: Marina P. Colella – Hemocentro UNICAMP, Department of Internal Medicine, School of Medical Sciences, University of Campinas

  Co-Author: Silmara A. L. Montalvão – 2Hemostasis and Thrombosis Laboratory, Hematology and Hemotherapy Center, University of Campinas (UNICAMP)

  Co-Author: Gabriela G. Yamaguti-Hayakawa – Hemocentro UNICAMP, Department of Internal Medicine, School of Medical Sciences, University of Campinas

  Co-Author: Margareth C. Ozelo, MD, PhD – Hemocentro UNICAMP, Department of Internal Medicine, School of Medical Sciences, University of Campinas