OC 77 - Platelets and MKs as Antithrombotic Targets

Moderator(s)

• 

  Amanda Unsworth, DPhil

  Senior Lecturer
  Department of Life Sciences, Centre for Bioscience
  Manchester Metropolitan University
  Manchester, England, United Kingdom
• 

  Marie Lordkipanidzé, B.Pharm, PhD

  Associate professor
  Research Center
  Faculty of pharmacy, University of Montreal
  Montreal, Quebec, Canada

Presentations:

• 10:15 AM – 10:30 AM

  Inhibition of the Class II PI 3-kinase, PI3KC2a, prevents thrombosis in hyperlipidaemic mice
  

  Presenting Author: Natasha M. Setiabakti, MD – Monash University

  Co-Author: Volga Tarlac – Australian Centre for Blood Diseases, Monash University

  Co-Author: Justin R. Hamilton – Australian Centre for Blood Diseases, Monash University
• 10:30 AM – 10:45 AM

  Na+/K+ ATPase alpha 1 subunit participates in platelet signaling and is a potential anti-thrombotic target
  

  Presenting Author: Oliver Li, Master of Science – Joan C. Edwards School of Medicine at Marshall University

  Co-Author: Rodrigo Aguilar – Department of Medicine, Joan C. Edwards School of Medicine

  Co-Author: Renat Roytenberg – Marshall University Joan C. Edwards School of Medicine

  Co-Author: Hong Yue – Joan C. Edwards School of Medicine at Marshall University

  Co-Author: Ellen Thompson – Department of Medicine, Joan C. Edwards School of Medicine

  Co-Author: Sandrine Pierre – Marshall Institute for Interdisciplinary Research

  Co-Author: Jiang Liu – Marshall University Joan C. Edwards School of Medicine

  Co-Author: Wei Li, MD, PhD – Joan C. Edwards School of Medicine at Marshall University
• 10:45 AM – 11:00 AM

  Platelet factor XIII-A regulates platelet function and promotes clot retraction and stability
  

  Presenting Author: Joanne Mitchell, PhD – University of Birmingham

  Co-Author: Gemma Little – University of Reading

  Co-Author: Alex Bye – St Georges University London

  Co-Author: Amanda J. Unsworth, DPhil – Manchester Metropolitan University

  Co-Author: Renato Gaspar – University of Reading

  Co-Author: Neline Kriek – University of Reading

  Co-Author: Tanya Sage – University of Reading

  Co-Author: Alexander Stainer – University of Reading

  Co-Author: Dayo Sangowawa – University of Reading

  Co-Author: Nicola Curry, MD, FRCP, FRCPath – Oxford University Hospitals NHS Foundation Trust

  Co-Author: Susan Shapiro, MD, PhD – Oxford University Hospitals National Health Service Foundation Trust, University of Oxford, and Oxford National Institute for Health Research Biomedical Research Centre

  Co-Author: Michael Desborough – Oxford University Hospitals NHS Foundation Trust

  Co-Author: Claire S. Whyte, PhD – University of Aberdeen

  Co-Author: Jonathan M. Gibbins, PhD – Institute for Cardiovascular and Metabolic Research, School of Biological sciences, University of Reading, Reading, UK

  Co-Author: Nicola J. Mutch, PhD – University of Aberdeen

  Co-Author: Chris Jones – Institute for Cardiovascular and Metabolic Research, School of Biological sciences, University of Reading, Reading, UK
• 11:00 AM – 11:15 AM

  Pharmacological targeting of GPV in a novel humanized mouse model to modulate thrombus formation in vivo
  

  Presenting Author: Patricia Öftering, MSc – University Hospital Würzburg and Rudolf Virchow Center for Integrative and Translational Bioimaging, University of Würzburg, Germany

  Co-Author: Sarah Beck, PhD – University Hospital and Rudolf Virchow Center, University of Würzburg

  Co-Author: David Stegner, PhD – University Hospital Würzburg and Rudolf Virchow Center for Integrative and Translational Biomaging University of Würzburg

  Co-Author: Bernhard Nieswandt – Institute of Experimental Biomedicine, University Hospital Würzburg and Rudolf Virchow Center for Integrative and Translational Bioimaging, University of Würzburg
• 11:15 AM – 11:30 AM

  Comprehensive analysis of human glycoprotein Ibα O-glycosylation.
  

  Presenting Author: Marie A. Hollenhorst, MD, PhD – Stanford University

  Co-Author: Katherine H. Tiemeyer – Stanford University

  Co-Author: Keira E. Mahoney – Yale University

  Co-Author: Kazuhiro Aoki – University of Georgia

  Co-Author: Mayumi Ishihara – University of Georgia

  Co-Author: Valentina Rangel-Angarita – Yale University

  Co-Author: Carolyn R. Bertozzi – Stanford University

  Co-Author: Stacy A. Malaker – Yale University