Sophie Hordijk, Msc

PhD student
Department of Hematology, Erasmus MC, University Medical Center Rotterdam, the Netherlands

Sophie Hordijk (Msc) is a PhD student in the department of Hematology at the Erasmus University Medical Center in Rotterdam, the Netherlands. Her research under the supervision of dr. ir. Ruben Bierings focuses on the molecular mechanisms of secretion in endothelial cells. Defects in these mechanisms can result in impaired release of the hemostatic protein Von Willebrand Factor, thereby causing bleeding problems. A unique tool in her research is the use of patient derived endothelial cells as a model to study specific mutations that cause secretion defects.

Presentation(s):

• OC 53.5 - Loss of Rab27A Targeting to Weibel-Palade Bodies in Endothelial Colony Forming Cells of Patients with Biallelic Mutations in the Guanine Nucleotide Exchange Factor MAP-Kinase Activating Death Domain

  Tuesday, July 12, 2022
  11:45 AM – 12:00 PM

• PB1261 - Delayed CCL26 trafficking in the secretory pathway of STX5 depleted Endothelial Cells

  Tuesday, July 12, 2022
  6:30 PM – 7:30 PM