Ophélie Le Chapelain

PhD student
INSERM

Ophélie LE CHAPELAIN, MD
3rd year PhD student in the group of Dr Benoît HO-TIN-NOE at Laboratory for Vascular Translation Science, Inserm U1148, located in Paris Bichat Hospital.

Our research focuses on how platelet-leukocyte interactions contribute to the pathophysiology of solid tumors. In particular, we investigate the participation of platelets in the development and regulation of the microvascular and immune environments of solid tumors.
Our objective is to promote basic science discoveries, in order to favor the development of new therapeutic strategies for the treatment of cancers.

Publications :
Le Chapelain, O.; Ho-Tin-Noé, B. Intratumoral Platelets: Harmful or Incidental Bystanders of the Tumor Microenvironment? Cancers 2022, 14, 2192. https://doi.org/10.3390/cancers14092192
Ho-Tin-Noé B, Le Chapelain O, Camerer E. Platelets maintain vascular barrier function in the absence of injury or inflammation. J Thromb Haemost. 2021;19(5):1145-1148. doi:10.1111/jth.15240
Jadoui S, Le Chapelain O, Ollivier V, et al. Glenzocimab does not impact glycoprotein VI-dependent inflammatory haemostasis. Haematologica. 2021;106(7):2000-2003. Published 2021 Jul 1. doi:10.3324/haematol.2020.270439

Presentation(s):

• PB0751 - Platelets are integral components of the tumor microenvironment whose regulatory actions vary with the tumor type

  Monday, July 11, 2022
  6:30 PM – 7:30 PM