Lecturer in Genetics
University of Hull
Dr. Daniel J. Hampshire, PhD, Lecturer of Genetics at the University of Hull, UK. My current position builds on 15 years of postdoctoral experience in the investigation of the plasma glycoprotein von Willebrand factor (VWF). Research in my group focuses specifically on identifying genetic factors that may contribute to the unusually wide variation in VWF plasma levels observed in the general population. An increased understanding of the factors influencing VWF levels has important implications given that variation in VWF levels is associated with susceptibility to both bleeding (reduced VWF levels) and thrombosis (elevated levels). My research in this area has investigated the transcriptional regulation of the VWF gene and other genetic modifiers of VWF level including single nucleotide variants within the VWF locus previously thought to be ‘neutral’ common polymorphisms. I have actively supervised five PhD projects as primary or secondary supervisor, and undertaken primary supervision of eleven MSc and four undergraduate vacation research projects; contributing to eight original papers (two as first author; three as senior author) and eighteen oral communications at national / international meetings from 2008-present.
My research contributions have led to me receiving International Society on Thrombosis and Haemostasis (ISTH) Young Investigator Awards (2009 and 2011), serving as co-chair of the ISTH Scientific and Standardization Committee on von Willebrand factor (2012-2015) and invitations to present my research at international conferences (2010, 2015 and 2017). In addition, skills I developed in the curation and interpretation of genetic variation data have led to roles with the European Association for Haemophilia and Allied Disorders, Human Genome Organisation and ClinGen (2011-present), helping to establish variant databases to provide researchers / clinicians with information on phenotype-genotype correlations.
Sunday, July 10, 2022
5:50 PM – 6:00 PM
Tuesday, July 12, 2022
6:30 PM – 7:30 PM