Matthew J. Flick, PhD

Professor
University of North Carolina at Chapel Hill

Dr. Matthew J. Flick, PhD is an Associate Professor at the University of North Cartolina at Chapel Hill in the Department of Pathology and Laboratory Medicine and the UNC Blood Reserach Center. The long-term goal of his research program is to identify and characterize novel mechanisms linking coagulation system factors to the progression of malignant, infectious, and inflammatory diseases. He has a long-standing interest in defining the functional relationship between hemostatic system components (e.g., prothrombin, fibrinogen, plasminogen) and the regulation of inflammation. Current projects in his research group center on undersatnding the controibution of the fibrinogen-plasminogen axis to pancreatic cancer, cancer-associated thrombosis, obesity and metabolic syndrome, S. aureus infection, and COVID-19. Recently, the Flick laboratory has initiated new projects focused on examining the impact of hypofibrinogenemia on hemostasis and thrombosis.

Presentation(s):

• OC 28.4 - Protective Role of Plasminogen Deficiency in Non-Alcoholic Fatty Liver Disease and Glucose Dysmetabolism

  Sunday, July 10, 2022
  3:30 PM – 3:45 PM

• OC 29.5 - Dysregulated fibrinogen γ-chain cross-linking in FibγΔ5 mice drives acute liver injury after acetaminophen overdose

  Sunday, July 10, 2022
  3:45 PM – 4:00 PM

• SSC 15.05 - Hypofibrinogenemia in Hemostasis and Thrombosis

  Monday, July 11, 2022
  5:00 PM – 5:10 PM

• MC 24.1 - Models to Understand Non-Hemostatic Roles of Fibrin(olysis)

  Tuesday, July 12, 2022
  1:15 PM – 2:00 PM